| Full name: desumoylating isopeptidase 2 | Alias Symbol: CGI-146|FLJ21998|PNAS-4 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 51029 | HGNC ID: HGNC:24264 | Ensembl Gene: ENSG00000121644 | OMIM ID: 614638 |
Expression of DESI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DESI2 | 51029 | 212371_at | 1.0432 | 0.0132 | |
| GSE20347 | DESI2 | 51029 | 212371_at | 0.8735 | 0.0000 | |
| GSE23400 | DESI2 | 51029 | 212371_at | 0.9215 | 0.0000 | |
| GSE26886 | DESI2 | 51029 | 212371_at | 0.6802 | 0.0053 | |
| GSE29001 | DESI2 | 51029 | 212371_at | 0.9154 | 0.0052 | |
| GSE38129 | DESI2 | 51029 | 212371_at | 0.8180 | 0.0000 | |
| GSE45670 | DESI2 | 51029 | 212371_at | 0.3844 | 0.0487 | |
| GSE53622 | DESI2 | 51029 | 33518 | 0.7719 | 0.0000 | |
| GSE53624 | DESI2 | 51029 | 33518 | 0.9104 | 0.0000 | |
| GSE63941 | DESI2 | 51029 | 212371_at | -0.8071 | 0.0228 | |
| GSE77861 | DESI2 | 51029 | 212371_at | 0.9893 | 0.0011 | |
| SRP007169 | DESI2 | 51029 | RNAseq | 0.4791 | 0.2295 | |
| SRP008496 | DESI2 | 51029 | RNAseq | 0.6448 | 0.0116 | |
| SRP064894 | DESI2 | 51029 | RNAseq | 0.5495 | 0.0002 | |
| SRP133303 | DESI2 | 51029 | RNAseq | 1.0184 | 0.0000 | |
| SRP159526 | DESI2 | 51029 | RNAseq | 0.7882 | 0.0019 | |
| SRP193095 | DESI2 | 51029 | RNAseq | 0.4122 | 0.0004 | |
| SRP219564 | DESI2 | 51029 | RNAseq | 0.5321 | 0.0337 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DESI2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of DESI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DESI2 | 51029 | 7 | 1 | 22 | |
| GSE20123 | DESI2 | 51029 | 7 | 1 | 22 | |
| GSE43470 | DESI2 | 51029 | 6 | 2 | 35 | |
| GSE46452 | DESI2 | 51029 | 4 | 2 | 53 | |
| GSE47630 | DESI2 | 51029 | 15 | 0 | 25 | |
| GSE54993 | DESI2 | 51029 | 0 | 6 | 64 | |
| GSE54994 | DESI2 | 51029 | 18 | 0 | 35 | |
| GSE60625 | DESI2 | 51029 | 0 | 0 | 11 | |
| GSE74703 | DESI2 | 51029 | 6 | 1 | 29 | |
| GSE74704 | DESI2 | 51029 | 2 | 0 | 18 | |
| TCGA | DESI2 | 51029 | 46 | 5 | 45 |
Total number of gains: 111; Total number of losses: 18; Total Number of normals: 359.
Somatic mutations of DESI2:
Generating mutation plots.
Highly correlated genes for DESI2:
Showing top 20/1520 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DESI2 | ECT2 | 0.807173 | 9 | 0 | 9 |
| DESI2 | C1orf131 | 0.792707 | 6 | 0 | 6 |
| DESI2 | TFB2M | 0.773382 | 10 | 0 | 10 |
| DESI2 | STARD7 | 0.768169 | 9 | 0 | 9 |
| DESI2 | RPS6KC1 | 0.765127 | 9 | 0 | 9 |
| DESI2 | XPO1 | 0.761975 | 9 | 0 | 9 |
| DESI2 | ACTL6A | 0.761649 | 10 | 0 | 10 |
| DESI2 | E2F6 | 0.760905 | 10 | 0 | 10 |
| DESI2 | TAF1A | 0.755605 | 10 | 0 | 9 |
| DESI2 | CERS2 | 0.752995 | 9 | 0 | 9 |
| DESI2 | TFRC | 0.752967 | 9 | 0 | 9 |
| DESI2 | MTERF3 | 0.752275 | 8 | 0 | 8 |
| DESI2 | MTHFD2 | 0.751747 | 9 | 0 | 9 |
| DESI2 | ILF2 | 0.749264 | 9 | 0 | 9 |
| DESI2 | RUVBL1 | 0.743688 | 10 | 0 | 10 |
| DESI2 | HEATR1 | 0.741899 | 10 | 0 | 10 |
| DESI2 | DUSP12 | 0.741552 | 10 | 0 | 9 |
| DESI2 | COG2 | 0.738594 | 10 | 0 | 9 |
| DESI2 | FLVCR1 | 0.738 | 6 | 0 | 5 |
| DESI2 | RAD21 | 0.737893 | 8 | 0 | 8 |
For details and further investigation, click here
