| Full name: tyrosylprotein sulfotransferase 2 | Alias Symbol: TANGO13B | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 8459 | HGNC ID: HGNC:12021 | Ensembl Gene: ENSG00000128294 | OMIM ID: 603126 |
| Drug and gene relationship at DGIdb | |||
Expression of TPST2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPST2 | 8459 | 204079_at | 0.5846 | 0.2216 | |
| GSE20347 | TPST2 | 8459 | 204079_at | 0.3096 | 0.0534 | |
| GSE23400 | TPST2 | 8459 | 204079_at | 0.5129 | 0.0000 | |
| GSE26886 | TPST2 | 8459 | 204079_at | 0.6454 | 0.0054 | |
| GSE29001 | TPST2 | 8459 | 204079_at | 0.4770 | 0.1039 | |
| GSE38129 | TPST2 | 8459 | 204079_at | 0.5987 | 0.0001 | |
| GSE45670 | TPST2 | 8459 | 204079_at | 0.8580 | 0.0001 | |
| GSE53622 | TPST2 | 8459 | 108554 | 0.5937 | 0.0000 | |
| GSE53624 | TPST2 | 8459 | 108554 | 0.4155 | 0.0000 | |
| GSE63941 | TPST2 | 8459 | 204079_at | 0.1844 | 0.8287 | |
| GSE77861 | TPST2 | 8459 | 204079_at | 0.2997 | 0.2928 | |
| GSE97050 | TPST2 | 8459 | A_23_P132226 | 0.7015 | 0.1729 | |
| SRP007169 | TPST2 | 8459 | RNAseq | -0.0337 | 0.9251 | |
| SRP008496 | TPST2 | 8459 | RNAseq | -0.0758 | 0.7073 | |
| SRP064894 | TPST2 | 8459 | RNAseq | 0.6073 | 0.0060 | |
| SRP133303 | TPST2 | 8459 | RNAseq | 0.2488 | 0.1951 | |
| SRP159526 | TPST2 | 8459 | RNAseq | 0.2152 | 0.5535 | |
| SRP193095 | TPST2 | 8459 | RNAseq | 0.2469 | 0.0735 | |
| SRP219564 | TPST2 | 8459 | RNAseq | 0.4671 | 0.2068 | |
| TCGA | TPST2 | 8459 | RNAseq | 0.3841 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TPST2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPST2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPST2 | 8459 | 3 | 5 | 22 | |
| GSE20123 | TPST2 | 8459 | 3 | 4 | 23 | |
| GSE43470 | TPST2 | 8459 | 4 | 6 | 33 | |
| GSE46452 | TPST2 | 8459 | 31 | 1 | 27 | |
| GSE47630 | TPST2 | 8459 | 8 | 5 | 27 | |
| GSE54993 | TPST2 | 8459 | 3 | 6 | 61 | |
| GSE54994 | TPST2 | 8459 | 11 | 8 | 34 | |
| GSE60625 | TPST2 | 8459 | 5 | 0 | 6 | |
| GSE74703 | TPST2 | 8459 | 3 | 5 | 28 | |
| GSE74704 | TPST2 | 8459 | 0 | 1 | 19 | |
| TCGA | TPST2 | 8459 | 26 | 14 | 56 |
Total number of gains: 97; Total number of losses: 55; Total Number of normals: 336.
Somatic mutations of TPST2:
Generating mutation plots.
Highly correlated genes for TPST2:
Showing top 20/577 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPST2 | IL21R | 0.715709 | 3 | 0 | 3 |
| TPST2 | FERMT3 | 0.698699 | 3 | 0 | 3 |
| TPST2 | POLB | 0.688489 | 3 | 0 | 3 |
| TPST2 | LTB | 0.653157 | 3 | 0 | 3 |
| TPST2 | RCC2 | 0.643017 | 5 | 0 | 4 |
| TPST2 | EML4 | 0.639471 | 5 | 0 | 5 |
| TPST2 | TMC8 | 0.637805 | 4 | 0 | 3 |
| TPST2 | LILRB1 | 0.634129 | 4 | 0 | 3 |
| TPST2 | RNASET2 | 0.631356 | 4 | 0 | 3 |
| TPST2 | SLC30A7 | 0.627125 | 5 | 0 | 4 |
| TPST2 | BID | 0.626547 | 11 | 0 | 11 |
| TPST2 | KIF11 | 0.624443 | 6 | 0 | 4 |
| TPST2 | STON2 | 0.623787 | 3 | 0 | 3 |
| TPST2 | CMTM7 | 0.623311 | 5 | 0 | 3 |
| TPST2 | TSPAN17 | 0.622634 | 3 | 0 | 3 |
| TPST2 | YIF1B | 0.621351 | 4 | 0 | 3 |
| TPST2 | TIGD2 | 0.616569 | 4 | 0 | 3 |
| TPST2 | MTHFD1L | 0.615482 | 3 | 0 | 3 |
| TPST2 | GTSE1 | 0.612305 | 4 | 0 | 3 |
| TPST2 | DSG2 | 0.608874 | 8 | 0 | 5 |
For details and further investigation, click here
