Full name: DNA polymerase beta	Alias Symbol:
Type: protein-coding gene	Cytoband: 8p11.21
Entrez ID: 5423	HGNC ID: HGNC:9174	Ensembl Gene: ENSG00000070501	OMIM ID: 174760
Drug and gene relationship at DGIdb

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Expression of POLB:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	POLB	5423	203616_at	0.4027	0.3681	Show
GSE20347	POLB	5423	203616_at	0.3110	0.0607	Show
GSE23400	POLB	5423	203616_at	0.1340	0.1562	Show
GSE26886	POLB	5423	203616_at	-0.8997	0.0043	Show
GSE29001	POLB	5423	203616_at	-0.0036	0.9921	Show
GSE38129	POLB	5423	203616_at	0.3792	0.0148	Show
GSE45670	POLB	5423	203616_at	0.5633	0.0043	Show
GSE53622	POLB	5423	24062	0.1841	0.0793	Show
GSE53624	POLB	5423	24062	-0.0838	0.4007	Show
GSE63941	POLB	5423	203616_at	-0.1217	0.7792	Show
GSE77861	POLB	5423	203616_at	-0.2088	0.5529	Show
GSE97050	POLB	5423	A_32_P34552	0.3825	0.2611	Show
SRP007169	POLB	5423	RNAseq	-0.2615	0.5891	Show
SRP008496	POLB	5423	RNAseq	-0.3351	0.2555	Show
SRP064894	POLB	5423	RNAseq	-0.1455	0.4980	Show
SRP133303	POLB	5423	RNAseq	0.3450	0.1496	Show
SRP159526	POLB	5423	RNAseq	-0.2067	0.5368	Show
SRP193095	POLB	5423	RNAseq	-0.1076	0.5671	Show
SRP219564	POLB	5423	RNAseq	-0.0710	0.8379	Show
TCGA	POLB	5423	RNAseq	0.3715	0.0001	Show

Upregulated datasets: 0; Downregulated datasets: 0.  Download Data

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Survival by POLB expression:

 

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Copy number change of POLB:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	POLB	5423	10	5	15	Show
GSE20123	POLB	5423	10	5	15	Show
GSE43470	POLB	5423	9	6	28	Show
GSE46452	POLB	5423	19	5	35	Show
GSE47630	POLB	5423	22	1	17	Show
GSE54993	POLB	5423	1	16	53	Show
GSE54994	POLB	5423	19	7	27	Show
GSE60625	POLB	5423	3	0	8	Show
GSE74703	POLB	5423	8	5	23	Show
GSE74704	POLB	5423	9	2	9	Show
TCGA	POLB	5423	41	22	33	Show

Total number of gains: 151; Total number of losses: 74; Total Number of normals: 263.  Download Data

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Somatic mutations of POLB:

 

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Highly correlated genes for POLB:

 

Showing top 20/250 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
POLB	XRCC6	0.841461	3	0	3
POLB	CMTM6	0.781547	4	0	4
POLB	THAP11	0.752598	3	0	3
POLB	CDC123	0.748851	4	0	3
POLB	ARPC1A	0.743528	4	0	4
POLB	FBXO16	0.729024	3	0	3
POLB	CSTF3	0.721713	3	0	3
POLB	ASF1A	0.720099	3	0	3
POLB	RAB2A	0.713293	4	0	4
POLB	HAS3	0.710662	3	0	3
POLB	FAF2	0.706399	3	0	3
POLB	PSMD1	0.705043	3	0	3
POLB	SLAMF7	0.701253	3	0	3
POLB	CDCA2	0.700924	3	0	3
POLB	CIAPIN1	0.699317	4	0	3
POLB	ARPC3	0.699036	4	0	4
POLB	ASCC3	0.693263	3	0	3
POLB	TPST2	0.688489	3	0	3
POLB	PSMD7	0.685673	3	0	3
POLB	PRDX4	0.685526	4	0	3

For details and further investigation, click here