KCNJ14

 

Full name: potassium inwardly rectifying channel subfamily J member 14 Alias Symbol: Kir2.4|IRK4
Type: protein-coding gene Cytoband: 19q13.33
Entrez ID: 3770 HGNC ID: HGNC:6260 Ensembl Gene: ENSG00000182324 OMIM ID: 603953
Drug and gene relationship at DGIdb

 

KCNJ14 involved pathways:

KEGG pathway Description View
hsa04921Oxytocin signaling pathway

 

Expression of KCNJ14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KCNJ14 3770 220776_at -0.2672 0.1780
GSE20347 KCNJ14 3770 220776_at -0.0103 0.9356
GSE23400 KCNJ14 3770 220776_at -0.0654 0.0642
GSE26886 KCNJ14 3770 220776_at -0.1653 0.0713
GSE29001 KCNJ14 3770 220776_at -0.0558 0.7896
GSE38129 KCNJ14 3770 220776_at -0.0145 0.8754
GSE45670 KCNJ14 3770 220776_at 0.2166 0.0333
GSE53622 KCNJ14 3770 115823 0.1816 0.2083
GSE53624 KCNJ14 3770 115823 0.6448 0.0000
GSE63941 KCNJ14 3770 220776_at 0.3603 0.1778
GSE77861 KCNJ14 3770 220776_at -0.0092 0.9314
GSE97050 KCNJ14 3770 A_23_P130764 0.2762 0.2232
SRP007169 KCNJ14 3770 RNAseq 0.8894 0.2388
SRP064894 KCNJ14 3770 RNAseq 0.6654 0.0136
SRP133303 KCNJ14 3770 RNAseq 0.2483 0.2125
SRP159526 KCNJ14 3770 RNAseq 1.1548 0.0204
SRP193095 KCNJ14 3770 RNAseq 0.4851 0.0029
SRP219564 KCNJ14 3770 RNAseq 0.0051 0.9894
TCGA KCNJ14 3770 RNAseq 0.4071 0.0009

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by KCNJ14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KCNJ14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KCNJ14 3770 4 4 22
GSE20123 KCNJ14 3770 4 3 23
GSE43470 KCNJ14 3770 4 11 28
GSE46452 KCNJ14 3770 45 1 13
GSE47630 KCNJ14 3770 9 6 25
GSE54993 KCNJ14 3770 17 4 49
GSE54994 KCNJ14 3770 4 14 35
GSE60625 KCNJ14 3770 9 0 2
GSE74703 KCNJ14 3770 4 7 25
GSE74704 KCNJ14 3770 4 1 15
TCGA KCNJ14 3770 15 18 63

Total number of gains: 119; Total number of losses: 69; Total Number of normals: 300.  

 

Somatic mutations of KCNJ14:

 

Generating mutation plots.

 

Highly correlated genes for KCNJ14:

 

Showing top 20/222 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KCNJ14MMP160.759936303
KCNJ14KCNV10.718251303
KCNJ14CLC0.702516303
KCNJ14TGFBR10.689107303
KCNJ14TMEM106A0.687005303
KCNJ14SNX150.682602303
KCNJ14VTI1A0.677798303
KCNJ14ZNF804B0.67454303
KCNJ14SREBF20.664449303
KCNJ14DNAJB70.662782303
KCNJ14BCAS20.654666303
KCNJ14ACRBP0.653157303
KCNJ14TAS2R40.652938605
KCNJ14SPOCK20.64468505
KCNJ14PTCD10.644575303
KCNJ14CHMP50.643743403
KCNJ14NEURL10.642675303
KCNJ14CAMK2N20.642482303
KCNJ14PPP3CC0.642431403
KCNJ14TMEM2340.638252303

For details and further investigation, click here