| Full name: protein arginine methyltransferase 2 | Alias Symbol: MGC111373 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 3275 | HGNC ID: HGNC:5186 | Ensembl Gene: ENSG00000160310 | OMIM ID: 601961 |
| Drug and gene relationship at DGIdb | |||
Expression of PRMT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRMT2 | 3275 | 228725_x_at | -0.6491 | 0.0148 | |
| GSE20347 | PRMT2 | 3275 | 221564_at | -0.7778 | 0.0000 | |
| GSE23400 | PRMT2 | 3275 | 202098_s_at | -0.0517 | 0.3966 | |
| GSE26886 | PRMT2 | 3275 | 202098_s_at | -0.8878 | 0.0007 | |
| GSE29001 | PRMT2 | 3275 | 221564_at | -0.2986 | 0.4057 | |
| GSE38129 | PRMT2 | 3275 | 221564_at | -0.6621 | 0.0000 | |
| GSE45670 | PRMT2 | 3275 | 228725_x_at | -0.4914 | 0.0046 | |
| GSE53622 | PRMT2 | 3275 | 1972 | -0.7020 | 0.0000 | |
| GSE53624 | PRMT2 | 3275 | 1972 | -0.8379 | 0.0000 | |
| GSE63941 | PRMT2 | 3275 | 228725_x_at | -0.0458 | 0.9461 | |
| GSE77861 | PRMT2 | 3275 | 228725_x_at | -0.8318 | 0.0248 | |
| GSE97050 | PRMT2 | 3275 | A_24_P151498 | -0.6875 | 0.0885 | |
| SRP007169 | PRMT2 | 3275 | RNAseq | -0.7097 | 0.0403 | |
| SRP008496 | PRMT2 | 3275 | RNAseq | -0.4267 | 0.1040 | |
| SRP064894 | PRMT2 | 3275 | RNAseq | 0.1528 | 0.5336 | |
| SRP133303 | PRMT2 | 3275 | RNAseq | -0.6652 | 0.0000 | |
| SRP159526 | PRMT2 | 3275 | RNAseq | -0.5427 | 0.0028 | |
| SRP193095 | PRMT2 | 3275 | RNAseq | -0.4502 | 0.0000 | |
| SRP219564 | PRMT2 | 3275 | RNAseq | -0.3095 | 0.4334 | |
| TCGA | PRMT2 | 3275 | RNAseq | -0.1144 | 0.0240 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRMT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRMT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRMT2 | 3275 | 3 | 9 | 18 | |
| GSE20123 | PRMT2 | 3275 | 3 | 9 | 18 | |
| GSE43470 | PRMT2 | 3275 | 0 | 14 | 29 | |
| GSE46452 | PRMT2 | 3275 | 1 | 21 | 37 | |
| GSE47630 | PRMT2 | 3275 | 6 | 17 | 17 | |
| GSE54993 | PRMT2 | 3275 | 8 | 1 | 61 | |
| GSE54994 | PRMT2 | 3275 | 5 | 8 | 40 | |
| GSE60625 | PRMT2 | 3275 | 0 | 0 | 11 | |
| GSE74703 | PRMT2 | 3275 | 0 | 10 | 26 | |
| GSE74704 | PRMT2 | 3275 | 1 | 5 | 14 | |
| TCGA | PRMT2 | 3275 | 10 | 37 | 49 |
Total number of gains: 37; Total number of losses: 131; Total Number of normals: 320.
Somatic mutations of PRMT2:
Generating mutation plots.
Highly correlated genes for PRMT2:
Showing top 20/1701 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRMT2 | RHBDD1 | 0.758669 | 3 | 0 | 3 |
| PRMT2 | NAA20 | 0.753518 | 3 | 0 | 3 |
| PRMT2 | CLEC3B | 0.751923 | 3 | 0 | 3 |
| PRMT2 | CCDC7 | 0.748963 | 3 | 0 | 3 |
| PRMT2 | RAB5A | 0.74319 | 9 | 0 | 9 |
| PRMT2 | GMPPB | 0.736968 | 3 | 0 | 3 |
| PRMT2 | BRK1 | 0.734 | 7 | 0 | 7 |
| PRMT2 | HIGD1A | 0.731681 | 9 | 0 | 9 |
| PRMT2 | ARGLU1 | 0.731137 | 3 | 0 | 3 |
| PRMT2 | FCHO2 | 0.731003 | 7 | 0 | 7 |
| PRMT2 | DCP1A | 0.729606 | 4 | 0 | 4 |
| PRMT2 | CHCHD4 | 0.72709 | 3 | 0 | 3 |
| PRMT2 | SLC30A4 | 0.72536 | 7 | 0 | 7 |
| PRMT2 | TMEM19 | 0.72474 | 5 | 0 | 5 |
| PRMT2 | FBXO8 | 0.722757 | 7 | 0 | 7 |
| PRMT2 | C5orf24 | 0.721248 | 3 | 0 | 3 |
| PRMT2 | SPAG8 | 0.720645 | 3 | 0 | 3 |
| PRMT2 | RHBDF1 | 0.720303 | 5 | 0 | 4 |
| PRMT2 | ICA1L | 0.717159 | 3 | 0 | 3 |
| PRMT2 | FBXL5 | 0.713668 | 9 | 0 | 9 |
For details and further investigation, click here
