| Full name: myelin transcription factor 1 | Alias Symbol: MTF1|MYTI|ZC2HC4A|NZF2|ZC2H2C1 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 4661 | HGNC ID: HGNC:7622 | Ensembl Gene: ENSG00000196132 | OMIM ID: 600379 |
| Drug and gene relationship at DGIdb | |||
Expression of MYT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYT1 | 4661 | 215822_x_at | -0.0079 | 0.9779 | |
| GSE20347 | MYT1 | 4661 | 215822_x_at | -0.0738 | 0.3668 | |
| GSE23400 | MYT1 | 4661 | 215822_x_at | -0.1340 | 0.0001 | |
| GSE26886 | MYT1 | 4661 | 215822_x_at | 0.2276 | 0.0059 | |
| GSE29001 | MYT1 | 4661 | 215822_x_at | -0.2243 | 0.1061 | |
| GSE38129 | MYT1 | 4661 | 215822_x_at | -0.1226 | 0.1431 | |
| GSE45670 | MYT1 | 4661 | 215822_x_at | -0.0300 | 0.7289 | |
| GSE53622 | MYT1 | 4661 | 18300 | 0.7055 | 0.0000 | |
| GSE53624 | MYT1 | 4661 | 18300 | 0.9707 | 0.0000 | |
| GSE63941 | MYT1 | 4661 | 215822_x_at | -0.0304 | 0.8319 | |
| GSE77861 | MYT1 | 4661 | 215822_x_at | -0.1647 | 0.1376 | |
| GSE97050 | MYT1 | 4661 | A_33_P3312676 | 0.1053 | 0.5703 | |
| TCGA | MYT1 | 4661 | RNAseq | -1.1080 | 0.0769 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYT1 | 4661 | 13 | 3 | 14 | |
| GSE20123 | MYT1 | 4661 | 13 | 3 | 14 | |
| GSE43470 | MYT1 | 4661 | 11 | 1 | 31 | |
| GSE46452 | MYT1 | 4661 | 35 | 0 | 24 | |
| GSE47630 | MYT1 | 4661 | 25 | 1 | 14 | |
| GSE54993 | MYT1 | 4661 | 0 | 17 | 53 | |
| GSE54994 | MYT1 | 4661 | 29 | 0 | 24 | |
| GSE60625 | MYT1 | 4661 | 0 | 0 | 11 | |
| GSE74703 | MYT1 | 4661 | 10 | 0 | 26 | |
| GSE74704 | MYT1 | 4661 | 10 | 1 | 9 | |
| TCGA | MYT1 | 4661 | 44 | 4 | 48 |
Total number of gains: 190; Total number of losses: 30; Total Number of normals: 268.
Somatic mutations of MYT1:
Generating mutation plots.
Highly correlated genes for MYT1:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYT1 | ART1 | 0.753626 | 4 | 0 | 4 |
| MYT1 | ETS1 | 0.740534 | 3 | 0 | 3 |
| MYT1 | UMOD | 0.739033 | 4 | 0 | 4 |
| MYT1 | TP53I11 | 0.722545 | 3 | 0 | 3 |
| MYT1 | CETN1 | 0.714007 | 4 | 0 | 4 |
| MYT1 | CLC | 0.713041 | 3 | 0 | 3 |
| MYT1 | TSHR | 0.709727 | 4 | 0 | 4 |
| MYT1 | NEU3 | 0.703718 | 5 | 0 | 5 |
| MYT1 | KRTAP5-8 | 0.701239 | 6 | 0 | 6 |
| MYT1 | GDF5 | 0.699304 | 5 | 0 | 5 |
| MYT1 | GPR12 | 0.696345 | 4 | 0 | 4 |
| MYT1 | SPATA9 | 0.693238 | 3 | 0 | 3 |
| MYT1 | BRINP2 | 0.690146 | 5 | 0 | 4 |
| MYT1 | LINC00563 | 0.689168 | 5 | 0 | 5 |
| MYT1 | IL17A | 0.68837 | 4 | 0 | 4 |
| MYT1 | CACNB1 | 0.688356 | 5 | 0 | 5 |
| MYT1 | MAMDC4 | 0.687313 | 3 | 0 | 3 |
| MYT1 | HS6ST1 | 0.686736 | 4 | 0 | 4 |
| MYT1 | LUZP4 | 0.685477 | 5 | 0 | 5 |
| MYT1 | C22orf31 | 0.683397 | 4 | 0 | 4 |
For details and further investigation, click here
