| Full name: tripartite motif containing 16 | Alias Symbol: EBBP | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 10626 | HGNC ID: HGNC:17241 | Ensembl Gene: ENSG00000221926 | OMIM ID: 609505 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM16 | 10626 | 204341_at | -1.4002 | 0.3344 | |
| GSE20347 | TRIM16 | 10626 | 204341_at | -1.1281 | 0.0023 | |
| GSE23400 | TRIM16 | 10626 | 204341_at | -0.7034 | 0.0000 | |
| GSE26886 | TRIM16 | 10626 | 204341_at | -2.0641 | 0.0003 | |
| GSE29001 | TRIM16 | 10626 | 204341_at | -1.8253 | 0.0001 | |
| GSE38129 | TRIM16 | 10626 | 204341_at | -0.3795 | 0.3687 | |
| GSE45670 | TRIM16 | 10626 | 204341_at | -0.1588 | 0.6755 | |
| GSE53622 | TRIM16 | 10626 | 26178 | 0.2665 | 0.0000 | |
| GSE53624 | TRIM16 | 10626 | 26178 | 0.0244 | 0.7151 | |
| GSE63941 | TRIM16 | 10626 | 204341_at | 2.8212 | 0.0124 | |
| GSE77861 | TRIM16 | 10626 | 204341_at | -0.3681 | 0.5414 | |
| GSE97050 | TRIM16 | 10626 | A_33_P3416687 | -0.3613 | 0.3513 | |
| SRP007169 | TRIM16 | 10626 | RNAseq | -2.8196 | 0.0000 | |
| SRP008496 | TRIM16 | 10626 | RNAseq | -2.2178 | 0.0000 | |
| SRP064894 | TRIM16 | 10626 | RNAseq | -2.1598 | 0.0000 | |
| SRP133303 | TRIM16 | 10626 | RNAseq | -1.3256 | 0.0000 | |
| SRP159526 | TRIM16 | 10626 | RNAseq | -0.9352 | 0.0366 | |
| SRP193095 | TRIM16 | 10626 | RNAseq | -0.7671 | 0.0004 | |
| SRP219564 | TRIM16 | 10626 | RNAseq | -1.4570 | 0.0358 | |
| TCGA | TRIM16 | 10626 | RNAseq | 0.2333 | 0.0169 |
Upregulated datasets: 1; Downregulated datasets: 8.
Survival by TRIM16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM16 | 10626 | 3 | 4 | 23 | |
| GSE20123 | TRIM16 | 10626 | 3 | 5 | 22 | |
| GSE43470 | TRIM16 | 10626 | 2 | 4 | 37 | |
| GSE46452 | TRIM16 | 10626 | 34 | 1 | 24 | |
| GSE47630 | TRIM16 | 10626 | 7 | 1 | 32 | |
| GSE54993 | TRIM16 | 10626 | 3 | 3 | 64 | |
| GSE54994 | TRIM16 | 10626 | 6 | 5 | 42 | |
| GSE60625 | TRIM16 | 10626 | 4 | 0 | 7 | |
| GSE74703 | TRIM16 | 10626 | 2 | 2 | 32 | |
| GSE74704 | TRIM16 | 10626 | 2 | 2 | 16 | |
| TCGA | TRIM16 | 10626 | 18 | 22 | 56 |
Total number of gains: 84; Total number of losses: 49; Total Number of normals: 355.
Somatic mutations of TRIM16:
Generating mutation plots.
Highly correlated genes for TRIM16:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM16 | TALDO1 | 0.67907 | 8 | 0 | 7 |
| TRIM16 | CCNYL1 | 0.660279 | 3 | 0 | 3 |
| TRIM16 | CLIC3 | 0.654917 | 6 | 0 | 5 |
| TRIM16 | PGLYRP4 | 0.645343 | 3 | 0 | 3 |
| TRIM16 | TTC5 | 0.638928 | 3 | 0 | 3 |
| TRIM16 | IQCF2 | 0.635858 | 3 | 0 | 3 |
| TRIM16 | ITGAD | 0.633347 | 4 | 0 | 4 |
| TRIM16 | NR1I3 | 0.625611 | 4 | 0 | 4 |
| TRIM16 | LRRC20 | 0.622766 | 4 | 0 | 3 |
| TRIM16 | RBX1 | 0.619314 | 4 | 0 | 3 |
| TRIM16 | ORMDL2 | 0.618905 | 7 | 0 | 5 |
| TRIM16 | CALM1 | 0.613015 | 3 | 0 | 3 |
| TRIM16 | TULP1 | 0.611198 | 3 | 0 | 3 |
| TRIM16 | UBE2G1 | 0.609425 | 8 | 0 | 7 |
| TRIM16 | RIT1 | 0.608017 | 10 | 0 | 7 |
| TRIM16 | TMEM184A | 0.60727 | 5 | 0 | 4 |
| TRIM16 | PRSS2 | 0.606567 | 6 | 0 | 3 |
| TRIM16 | HBZ | 0.605637 | 4 | 0 | 3 |
| TRIM16 | IL22RA1 | 0.604404 | 8 | 0 | 5 |
| TRIM16 | C2CD4D | 0.600425 | 3 | 0 | 3 |
For details and further investigation, click here
