| Full name: peptidoglycan recognition protein 4 | Alias Symbol: SBBI67|PGRPIB|PGLYRPIbeta|PGRP-Ibeta | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 57115 | HGNC ID: HGNC:30015 | Ensembl Gene: ENSG00000163218 | OMIM ID: 608198 |
| Drug and gene relationship at DGIdb | |||
Expression of PGLYRP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGLYRP4 | 57115 | 220944_at | 0.0216 | 0.9841 | |
| GSE20347 | PGLYRP4 | 57115 | 220944_at | -0.1429 | 0.4482 | |
| GSE23400 | PGLYRP4 | 57115 | 220944_at | -0.0616 | 0.4482 | |
| GSE26886 | PGLYRP4 | 57115 | 220944_at | -0.8728 | 0.0083 | |
| GSE29001 | PGLYRP4 | 57115 | 220944_at | -0.1231 | 0.8169 | |
| GSE38129 | PGLYRP4 | 57115 | 220944_at | -0.2230 | 0.3012 | |
| GSE45670 | PGLYRP4 | 57115 | 220944_at | 0.4835 | 0.0572 | |
| GSE53622 | PGLYRP4 | 57115 | 139 | 0.4692 | 0.2206 | |
| GSE53624 | PGLYRP4 | 57115 | 139 | -0.4652 | 0.0530 | |
| GSE63941 | PGLYRP4 | 57115 | 220944_at | 0.5595 | 0.0424 | |
| GSE77861 | PGLYRP4 | 57115 | 220944_at | 0.2191 | 0.6645 | |
| GSE97050 | PGLYRP4 | 57115 | A_24_P231302 | 0.9071 | 0.1949 | |
| SRP007169 | PGLYRP4 | 57115 | RNAseq | -3.0383 | 0.0000 | |
| SRP008496 | PGLYRP4 | 57115 | RNAseq | -1.5223 | 0.0084 | |
| SRP064894 | PGLYRP4 | 57115 | RNAseq | -0.3883 | 0.3906 | |
| SRP133303 | PGLYRP4 | 57115 | RNAseq | -0.3689 | 0.5433 | |
| SRP159526 | PGLYRP4 | 57115 | RNAseq | -0.4647 | 0.5956 | |
| SRP219564 | PGLYRP4 | 57115 | RNAseq | -1.7803 | 0.1280 | |
| TCGA | PGLYRP4 | 57115 | RNAseq | 1.7357 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by PGLYRP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGLYRP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PGLYRP4 | 57115 | 14 | 0 | 16 | |
| GSE20123 | PGLYRP4 | 57115 | 14 | 0 | 16 | |
| GSE43470 | PGLYRP4 | 57115 | 6 | 2 | 35 | |
| GSE46452 | PGLYRP4 | 57115 | 2 | 1 | 56 | |
| GSE47630 | PGLYRP4 | 57115 | 15 | 0 | 25 | |
| GSE54993 | PGLYRP4 | 57115 | 0 | 4 | 66 | |
| GSE54994 | PGLYRP4 | 57115 | 16 | 0 | 37 | |
| GSE60625 | PGLYRP4 | 57115 | 0 | 0 | 11 | |
| GSE74703 | PGLYRP4 | 57115 | 6 | 1 | 29 | |
| GSE74704 | PGLYRP4 | 57115 | 7 | 0 | 13 | |
| TCGA | PGLYRP4 | 57115 | 40 | 2 | 54 |
Total number of gains: 120; Total number of losses: 10; Total Number of normals: 358.
Somatic mutations of PGLYRP4:
Generating mutation plots.
Highly correlated genes for PGLYRP4:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGLYRP4 | MCTP1 | 0.672797 | 3 | 0 | 3 |
| PGLYRP4 | C11orf72 | 0.666511 | 3 | 0 | 3 |
| PGLYRP4 | PGLYRP3 | 0.66449 | 4 | 0 | 3 |
| PGLYRP4 | CERS3 | 0.661154 | 6 | 0 | 5 |
| PGLYRP4 | DTWD2 | 0.645983 | 3 | 0 | 3 |
| PGLYRP4 | LILRB1 | 0.645894 | 3 | 0 | 3 |
| PGLYRP4 | TRIM16 | 0.645343 | 3 | 0 | 3 |
| PGLYRP4 | SLC35A4 | 0.645145 | 4 | 0 | 3 |
| PGLYRP4 | POM121L2 | 0.642159 | 3 | 0 | 3 |
| PGLYRP4 | SGPP2 | 0.640681 | 5 | 0 | 4 |
| PGLYRP4 | SIRPB1 | 0.638236 | 4 | 0 | 4 |
| PGLYRP4 | DND1 | 0.637371 | 4 | 0 | 4 |
| PGLYRP4 | AP3B1 | 0.637246 | 3 | 0 | 3 |
| PGLYRP4 | CINP | 0.636658 | 3 | 0 | 3 |
| PGLYRP4 | TRIM62 | 0.635689 | 4 | 0 | 3 |
| PGLYRP4 | LRRC28 | 0.633022 | 3 | 0 | 3 |
| PGLYRP4 | DMBT1 | 0.629214 | 3 | 0 | 3 |
| PGLYRP4 | USP40 | 0.629032 | 3 | 0 | 3 |
| PGLYRP4 | MOSPD3 | 0.626104 | 3 | 0 | 3 |
| PGLYRP4 | NIPAL4 | 0.624905 | 5 | 0 | 3 |
For details and further investigation, click here
