| Full name: ubiquitin conjugating enzyme E2 G1 | Alias Symbol: UBC7 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 7326 | HGNC ID: HGNC:12482 | Ensembl Gene: ENSG00000132388 | OMIM ID: 601569 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2G1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2G1 | 7326 | 209141_at | -0.4315 | 0.2265 | |
| GSE20347 | UBE2G1 | 7326 | 209141_at | -1.0536 | 0.0000 | |
| GSE23400 | UBE2G1 | 7326 | 209141_at | -0.5383 | 0.0000 | |
| GSE26886 | UBE2G1 | 7326 | 209141_at | -1.2087 | 0.0000 | |
| GSE29001 | UBE2G1 | 7326 | 209141_at | -0.6512 | 0.0009 | |
| GSE38129 | UBE2G1 | 7326 | 209141_at | -0.7225 | 0.0001 | |
| GSE45670 | UBE2G1 | 7326 | 209141_at | -0.2981 | 0.0808 | |
| GSE53622 | UBE2G1 | 7326 | 28437 | -0.3766 | 0.0000 | |
| GSE53624 | UBE2G1 | 7326 | 28437 | -0.6672 | 0.0000 | |
| GSE63941 | UBE2G1 | 7326 | 209141_at | 1.0491 | 0.0008 | |
| GSE77861 | UBE2G1 | 7326 | 209141_at | -0.5539 | 0.0727 | |
| GSE97050 | UBE2G1 | 7326 | A_23_P27066 | -0.3932 | 0.1403 | |
| SRP007169 | UBE2G1 | 7326 | RNAseq | -1.9297 | 0.0000 | |
| SRP008496 | UBE2G1 | 7326 | RNAseq | -1.7811 | 0.0000 | |
| SRP064894 | UBE2G1 | 7326 | RNAseq | -1.2758 | 0.0000 | |
| SRP133303 | UBE2G1 | 7326 | RNAseq | -0.5040 | 0.0000 | |
| SRP159526 | UBE2G1 | 7326 | RNAseq | -0.7803 | 0.0047 | |
| SRP193095 | UBE2G1 | 7326 | RNAseq | -0.7990 | 0.0000 | |
| SRP219564 | UBE2G1 | 7326 | RNAseq | -1.3307 | 0.0001 | |
| TCGA | UBE2G1 | 7326 | RNAseq | 0.0335 | 0.4681 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by UBE2G1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2G1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2G1 | 7326 | 5 | 2 | 23 | |
| GSE20123 | UBE2G1 | 7326 | 5 | 3 | 22 | |
| GSE43470 | UBE2G1 | 7326 | 1 | 6 | 36 | |
| GSE46452 | UBE2G1 | 7326 | 34 | 1 | 24 | |
| GSE47630 | UBE2G1 | 7326 | 7 | 1 | 32 | |
| GSE54993 | UBE2G1 | 7326 | 4 | 3 | 63 | |
| GSE54994 | UBE2G1 | 7326 | 5 | 9 | 39 | |
| GSE60625 | UBE2G1 | 7326 | 4 | 0 | 7 | |
| GSE74703 | UBE2G1 | 7326 | 1 | 3 | 32 | |
| GSE74704 | UBE2G1 | 7326 | 3 | 1 | 16 | |
| TCGA | UBE2G1 | 7326 | 18 | 22 | 56 |
Total number of gains: 87; Total number of losses: 51; Total Number of normals: 350.
Somatic mutations of UBE2G1:
Generating mutation plots.
Highly correlated genes for UBE2G1:
Showing top 20/1177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2G1 | TPD52L2 | 0.758354 | 3 | 0 | 3 |
| UBE2G1 | FRMD4B | 0.737541 | 11 | 0 | 11 |
| UBE2G1 | C18orf25 | 0.734655 | 11 | 0 | 11 |
| UBE2G1 | IRAK2 | 0.733121 | 3 | 0 | 3 |
| UBE2G1 | GYS2 | 0.725859 | 10 | 0 | 10 |
| UBE2G1 | MXD1 | 0.724551 | 11 | 0 | 10 |
| UBE2G1 | GDPD3 | 0.723913 | 10 | 0 | 10 |
| UBE2G1 | ITCH | 0.723785 | 10 | 0 | 10 |
| UBE2G1 | ACOX1 | 0.723561 | 10 | 0 | 9 |
| UBE2G1 | ACPP | 0.723432 | 10 | 0 | 10 |
| UBE2G1 | CAST | 0.722223 | 11 | 0 | 11 |
| UBE2G1 | PADI1 | 0.721282 | 9 | 0 | 9 |
| UBE2G1 | PRPF38A | 0.720456 | 3 | 0 | 3 |
| UBE2G1 | NAA35 | 0.718502 | 3 | 0 | 3 |
| UBE2G1 | ARSG | 0.717738 | 3 | 0 | 3 |
| UBE2G1 | SLC16A6 | 0.71744 | 11 | 0 | 11 |
| UBE2G1 | FAM122C | 0.716743 | 4 | 0 | 4 |
| UBE2G1 | NPEPPS | 0.716736 | 11 | 0 | 11 |
| UBE2G1 | ALG13 | 0.715801 | 3 | 0 | 3 |
| UBE2G1 | CLIC3 | 0.715073 | 8 | 0 | 8 |
For details and further investigation, click here
