| Full name: tripartite motif containing 40 | Alias Symbol: RNF35 | ||
| Type: protein-coding gene | Cytoband: 6p22.1 | ||
| Entrez ID: 135644 | HGNC ID: HGNC:18736 | Ensembl Gene: ENSG00000204614 | OMIM ID: 616976 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM40:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM40 | 135644 | 1553079_at | -0.2124 | 0.4729 | |
| GSE26886 | TRIM40 | 135644 | 1553079_at | -0.0636 | 0.6010 | |
| GSE45670 | TRIM40 | 135644 | 1553079_at | -0.1066 | 0.3345 | |
| GSE53622 | TRIM40 | 135644 | 6378 | 0.0912 | 0.3309 | |
| GSE53624 | TRIM40 | 135644 | 6378 | 0.2756 | 0.0084 | |
| GSE63941 | TRIM40 | 135644 | 1553079_at | 0.1104 | 0.4464 | |
| GSE77861 | TRIM40 | 135644 | 1553079_at | -0.1492 | 0.0769 | |
| TCGA | TRIM40 | 135644 | RNAseq | -2.5360 | 0.0762 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRIM40 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM40:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM40 | 135644 | 4 | 1 | 25 | |
| GSE20123 | TRIM40 | 135644 | 4 | 1 | 25 | |
| GSE43470 | TRIM40 | 135644 | 5 | 0 | 38 | |
| GSE46452 | TRIM40 | 135644 | 1 | 10 | 48 | |
| GSE47630 | TRIM40 | 135644 | 7 | 3 | 30 | |
| GSE54993 | TRIM40 | 135644 | 2 | 1 | 67 | |
| GSE54994 | TRIM40 | 135644 | 11 | 4 | 38 | |
| GSE60625 | TRIM40 | 135644 | 0 | 1 | 10 | |
| GSE74703 | TRIM40 | 135644 | 5 | 0 | 31 | |
| GSE74704 | TRIM40 | 135644 | 2 | 0 | 18 | |
| TCGA | TRIM40 | 135644 | 16 | 17 | 63 |
Total number of gains: 57; Total number of losses: 38; Total Number of normals: 393.
Somatic mutations of TRIM40:
Generating mutation plots.
Highly correlated genes for TRIM40:
Showing top 20/111 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM40 | BLOC1S1 | 0.674991 | 3 | 0 | 3 |
| TRIM40 | PLK3 | 0.644702 | 3 | 0 | 3 |
| TRIM40 | AGFG2 | 0.63763 | 3 | 0 | 3 |
| TRIM40 | CD244 | 0.636317 | 3 | 0 | 3 |
| TRIM40 | MYO15A | 0.632386 | 3 | 0 | 3 |
| TRIM40 | MIEF2 | 0.627573 | 3 | 0 | 3 |
| TRIM40 | RNF208 | 0.62718 | 3 | 0 | 3 |
| TRIM40 | ARHGEF10L | 0.626043 | 3 | 0 | 3 |
| TRIM40 | USP54 | 0.623658 | 3 | 0 | 3 |
| TRIM40 | MYOD1 | 0.621881 | 3 | 0 | 3 |
| TRIM40 | LINC00470 | 0.61994 | 4 | 0 | 3 |
| TRIM40 | TRPM8 | 0.617784 | 4 | 0 | 4 |
| TRIM40 | ASB12 | 0.613918 | 3 | 0 | 3 |
| TRIM40 | CREB3L3 | 0.612372 | 3 | 0 | 3 |
| TRIM40 | TJP3 | 0.611178 | 3 | 0 | 3 |
| TRIM40 | C5orf66-AS1 | 0.608833 | 3 | 0 | 3 |
| TRIM40 | BTNL2 | 0.608108 | 5 | 0 | 3 |
| TRIM40 | VSIG2 | 0.601807 | 3 | 0 | 3 |
| TRIM40 | FAM95B1 | 0.600812 | 4 | 0 | 3 |
| TRIM40 | RMND5B | 0.598369 | 3 | 0 | 3 |
For details and further investigation, click here
