| Full name: sperm associated antigen 7 | Alias Symbol: FSA-1|ACRP|MGC20134 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 9552 | HGNC ID: HGNC:11216 | Ensembl Gene: ENSG00000091640 | OMIM ID: 610056 |
| Drug and gene relationship at DGIdb | |||
Expression of SPAG7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPAG7 | 9552 | 200053_at | -0.1906 | 0.5549 | |
| GSE20347 | SPAG7 | 9552 | 200053_at | -0.0720 | 0.3203 | |
| GSE23400 | SPAG7 | 9552 | 200053_at | 0.0372 | 0.4788 | |
| GSE26886 | SPAG7 | 9552 | 200053_at | 0.3170 | 0.0354 | |
| GSE29001 | SPAG7 | 9552 | 200053_at | -0.0904 | 0.6562 | |
| GSE38129 | SPAG7 | 9552 | 200053_at | -0.0989 | 0.1731 | |
| GSE45670 | SPAG7 | 9552 | 200053_at | -0.0678 | 0.5787 | |
| GSE53622 | SPAG7 | 9552 | 14494 | -0.1021 | 0.0945 | |
| GSE53624 | SPAG7 | 9552 | 14494 | -0.1092 | 0.2132 | |
| GSE63941 | SPAG7 | 9552 | 200053_at | -0.5574 | 0.1474 | |
| GSE77861 | SPAG7 | 9552 | 200053_at | 0.1623 | 0.3607 | |
| GSE97050 | SPAG7 | 9552 | A_23_P218412 | -0.0627 | 0.7875 | |
| SRP007169 | SPAG7 | 9552 | RNAseq | 0.6448 | 0.2675 | |
| SRP064894 | SPAG7 | 9552 | RNAseq | 0.3500 | 0.1752 | |
| SRP133303 | SPAG7 | 9552 | RNAseq | -0.1619 | 0.2356 | |
| SRP159526 | SPAG7 | 9552 | RNAseq | 0.0588 | 0.6682 | |
| SRP193095 | SPAG7 | 9552 | RNAseq | -0.0628 | 0.5732 | |
| SRP219564 | SPAG7 | 9552 | RNAseq | 0.3839 | 0.2962 | |
| TCGA | SPAG7 | 9552 | RNAseq | -0.0789 | 0.1527 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPAG7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPAG7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPAG7 | 9552 | 5 | 2 | 23 | |
| GSE20123 | SPAG7 | 9552 | 5 | 3 | 22 | |
| GSE43470 | SPAG7 | 9552 | 1 | 6 | 36 | |
| GSE46452 | SPAG7 | 9552 | 34 | 1 | 24 | |
| GSE47630 | SPAG7 | 9552 | 7 | 1 | 32 | |
| GSE54993 | SPAG7 | 9552 | 4 | 3 | 63 | |
| GSE54994 | SPAG7 | 9552 | 5 | 9 | 39 | |
| GSE60625 | SPAG7 | 9552 | 4 | 0 | 7 | |
| GSE74703 | SPAG7 | 9552 | 1 | 3 | 32 | |
| GSE74704 | SPAG7 | 9552 | 3 | 1 | 16 | |
| TCGA | SPAG7 | 9552 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of SPAG7:
Generating mutation plots.
Highly correlated genes for SPAG7:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPAG7 | MLH3 | 0.752045 | 3 | 0 | 3 |
| SPAG7 | PHRF1 | 0.734084 | 3 | 0 | 3 |
| SPAG7 | SGTB | 0.719296 | 3 | 0 | 3 |
| SPAG7 | ENOSF1 | 0.714099 | 3 | 0 | 3 |
| SPAG7 | MYH10 | 0.711882 | 3 | 0 | 3 |
| SPAG7 | DYNC1I2 | 0.704727 | 3 | 0 | 3 |
| SPAG7 | NAP1L4 | 0.685154 | 3 | 0 | 3 |
| SPAG7 | MYC | 0.681957 | 4 | 0 | 3 |
| SPAG7 | OCIAD1 | 0.677898 | 3 | 0 | 3 |
| SPAG7 | IGF2R | 0.675516 | 3 | 0 | 3 |
| SPAG7 | CHURC1 | 0.670174 | 3 | 0 | 3 |
| SPAG7 | TXNDC15 | 0.666349 | 3 | 0 | 3 |
| SPAG7 | B3GNT9 | 0.663571 | 3 | 0 | 3 |
| SPAG7 | CAMKK2 | 0.662384 | 3 | 0 | 3 |
| SPAG7 | MSN | 0.661532 | 3 | 0 | 3 |
| SPAG7 | ABL1 | 0.661122 | 4 | 0 | 3 |
| SPAG7 | TRIM50 | 0.6535 | 3 | 0 | 3 |
| SPAG7 | FAU | 0.651173 | 4 | 0 | 3 |
| SPAG7 | MCL1 | 0.645001 | 4 | 0 | 3 |
| SPAG7 | EIF3F | 0.637798 | 4 | 0 | 3 |
For details and further investigation, click here
