| Full name: aquarius intron-binding spliceosomal factor | Alias Symbol: KIAA0560|fSAP164|IBP160 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 9716 | HGNC ID: HGNC:29513 | Ensembl Gene: ENSG00000021776 | OMIM ID: 610548 |
| Drug and gene relationship at DGIdb | |||
Expression of AQR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AQR | 9716 | 212584_at | -0.0081 | 0.9920 | |
| GSE20347 | AQR | 9716 | 212584_at | 0.1444 | 0.6511 | |
| GSE23400 | AQR | 9716 | 212584_at | 0.1480 | 0.0506 | |
| GSE26886 | AQR | 9716 | 212584_at | -0.4359 | 0.0086 | |
| GSE29001 | AQR | 9716 | 212584_at | -0.1724 | 0.7395 | |
| GSE38129 | AQR | 9716 | 212584_at | 0.1000 | 0.6450 | |
| GSE45670 | AQR | 9716 | 212584_at | 0.0345 | 0.8338 | |
| GSE53622 | AQR | 9716 | 22737 | 0.0332 | 0.6037 | |
| GSE53624 | AQR | 9716 | 22737 | -0.1242 | 0.0140 | |
| GSE63941 | AQR | 9716 | 212584_at | 0.2547 | 0.3765 | |
| GSE77861 | AQR | 9716 | 212584_at | -0.0111 | 0.9756 | |
| GSE97050 | AQR | 9716 | A_24_P280378 | 0.0940 | 0.6756 | |
| SRP007169 | AQR | 9716 | RNAseq | -0.0831 | 0.8041 | |
| SRP008496 | AQR | 9716 | RNAseq | -0.2025 | 0.4054 | |
| SRP064894 | AQR | 9716 | RNAseq | -0.3404 | 0.0792 | |
| SRP133303 | AQR | 9716 | RNAseq | -0.0461 | 0.7238 | |
| SRP159526 | AQR | 9716 | RNAseq | -0.3153 | 0.2931 | |
| SRP193095 | AQR | 9716 | RNAseq | -0.1913 | 0.0152 | |
| SRP219564 | AQR | 9716 | RNAseq | -0.6300 | 0.0319 | |
| TCGA | AQR | 9716 | RNAseq | 0.0350 | 0.4570 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AQR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AQR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AQR | 9716 | 3 | 6 | 21 | |
| GSE20123 | AQR | 9716 | 3 | 6 | 21 | |
| GSE43470 | AQR | 9716 | 4 | 4 | 35 | |
| GSE46452 | AQR | 9716 | 3 | 7 | 49 | |
| GSE47630 | AQR | 9716 | 8 | 11 | 21 | |
| GSE54993 | AQR | 9716 | 4 | 6 | 60 | |
| GSE54994 | AQR | 9716 | 5 | 8 | 40 | |
| GSE60625 | AQR | 9716 | 4 | 0 | 7 | |
| GSE74703 | AQR | 9716 | 4 | 3 | 29 | |
| GSE74704 | AQR | 9716 | 2 | 5 | 13 | |
| TCGA | AQR | 9716 | 13 | 20 | 63 |
Total number of gains: 53; Total number of losses: 76; Total Number of normals: 359.
Somatic mutations of AQR:
Generating mutation plots.
Highly correlated genes for AQR:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AQR | EIF4G2 | 0.827346 | 3 | 0 | 3 |
| AQR | GFPT1 | 0.792238 | 3 | 0 | 3 |
| AQR | KCTD15 | 0.78486 | 4 | 0 | 4 |
| AQR | ANKS6 | 0.783994 | 3 | 0 | 3 |
| AQR | FBXL5 | 0.783209 | 3 | 0 | 3 |
| AQR | TRMT11 | 0.772672 | 3 | 0 | 3 |
| AQR | TRERF1 | 0.771852 | 3 | 0 | 3 |
| AQR | POLG | 0.76093 | 5 | 0 | 5 |
| AQR | NOTCH2 | 0.756328 | 3 | 0 | 3 |
| AQR | QRICH1 | 0.75118 | 3 | 0 | 3 |
| AQR | VDAC3 | 0.733412 | 4 | 0 | 4 |
| AQR | TRUB1 | 0.731619 | 3 | 0 | 3 |
| AQR | DNMBP | 0.731145 | 3 | 0 | 3 |
| AQR | REST | 0.728983 | 3 | 0 | 3 |
| AQR | TXLNA | 0.728257 | 3 | 0 | 3 |
| AQR | INPP1 | 0.727104 | 3 | 0 | 3 |
| AQR | ACER3 | 0.726668 | 4 | 0 | 4 |
| AQR | MASTL | 0.725149 | 3 | 0 | 3 |
| AQR | TMBIM4 | 0.722973 | 3 | 0 | 3 |
| AQR | PRMT6 | 0.720776 | 3 | 0 | 3 |
For details and further investigation, click here
