| Full name: tRNA methyltransferase 1 like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.3 | ||
| Entrez ID: 81627 | HGNC ID: HGNC:16782 | Ensembl Gene: ENSG00000121486 | OMIM ID: 611673 |
| Drug and gene relationship at DGIdb | |||
Expression of TRMT1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMT1L | 81627 | 223404_s_at | -0.0327 | 0.9594 | |
| GSE20347 | TRMT1L | 81627 | 220992_s_at | -0.3137 | 0.0606 | |
| GSE23400 | TRMT1L | 81627 | 220992_s_at | -0.0513 | 0.3471 | |
| GSE26886 | TRMT1L | 81627 | 223404_s_at | -0.6558 | 0.0028 | |
| GSE29001 | TRMT1L | 81627 | 220992_s_at | -0.1023 | 0.8473 | |
| GSE38129 | TRMT1L | 81627 | 220992_s_at | -0.3162 | 0.0484 | |
| GSE45670 | TRMT1L | 81627 | 220992_s_at | -0.0876 | 0.7204 | |
| GSE53622 | TRMT1L | 81627 | 49587 | -0.2560 | 0.0051 | |
| GSE53624 | TRMT1L | 81627 | 49587 | -0.2913 | 0.0003 | |
| GSE63941 | TRMT1L | 81627 | 223404_s_at | 0.2492 | 0.5871 | |
| GSE77861 | TRMT1L | 81627 | 220992_s_at | 0.0352 | 0.8710 | |
| GSE97050 | TRMT1L | 81627 | A_24_P190877 | -0.3222 | 0.2025 | |
| SRP007169 | TRMT1L | 81627 | RNAseq | -0.2382 | 0.5652 | |
| SRP008496 | TRMT1L | 81627 | RNAseq | 0.7099 | 0.0502 | |
| SRP064894 | TRMT1L | 81627 | RNAseq | -0.1285 | 0.4874 | |
| SRP133303 | TRMT1L | 81627 | RNAseq | 0.2709 | 0.2018 | |
| SRP159526 | TRMT1L | 81627 | RNAseq | 0.1318 | 0.6719 | |
| SRP193095 | TRMT1L | 81627 | RNAseq | 0.0290 | 0.7794 | |
| SRP219564 | TRMT1L | 81627 | RNAseq | 0.1379 | 0.6102 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRMT1L expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TRMT1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMT1L | 81627 | 12 | 0 | 18 | |
| GSE20123 | TRMT1L | 81627 | 12 | 0 | 18 | |
| GSE43470 | TRMT1L | 81627 | 7 | 1 | 35 | |
| GSE46452 | TRMT1L | 81627 | 3 | 1 | 55 | |
| GSE47630 | TRMT1L | 81627 | 14 | 0 | 26 | |
| GSE54993 | TRMT1L | 81627 | 0 | 6 | 64 | |
| GSE54994 | TRMT1L | 81627 | 15 | 0 | 38 | |
| GSE60625 | TRMT1L | 81627 | 0 | 0 | 11 | |
| GSE74703 | TRMT1L | 81627 | 7 | 1 | 28 | |
| GSE74704 | TRMT1L | 81627 | 5 | 0 | 15 | |
| TCGA | TRMT1L | 81627 | 40 | 4 | 52 |
Total number of gains: 115; Total number of losses: 13; Total Number of normals: 360.
Somatic mutations of TRMT1L:
Generating mutation plots.
Highly correlated genes for TRMT1L:
Showing top 20/433 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMT1L | TMCC3 | 0.796911 | 3 | 0 | 3 |
| TRMT1L | DOK4 | 0.748569 | 3 | 0 | 3 |
| TRMT1L | WDR47 | 0.73729 | 3 | 0 | 3 |
| TRMT1L | CCNYL1 | 0.731628 | 3 | 0 | 3 |
| TRMT1L | ATG2B | 0.731024 | 3 | 0 | 3 |
| TRMT1L | POLE3 | 0.728614 | 3 | 0 | 3 |
| TRMT1L | SYPL1 | 0.722334 | 3 | 0 | 3 |
| TRMT1L | NDUFA10 | 0.717797 | 4 | 0 | 4 |
| TRMT1L | SNX12 | 0.713826 | 3 | 0 | 3 |
| TRMT1L | COQ9 | 0.707652 | 4 | 0 | 3 |
| TRMT1L | RSPRY1 | 0.684199 | 3 | 0 | 3 |
| TRMT1L | NKIRAS1 | 0.681641 | 4 | 0 | 3 |
| TRMT1L | NR2C2 | 0.676713 | 4 | 0 | 3 |
| TRMT1L | RAB21 | 0.676577 | 4 | 0 | 3 |
| TRMT1L | TRIP11 | 0.675994 | 4 | 0 | 3 |
| TRMT1L | SENP8 | 0.675417 | 4 | 0 | 3 |
| TRMT1L | FOPNL | 0.674642 | 3 | 0 | 3 |
| TRMT1L | TK2 | 0.674211 | 4 | 0 | 4 |
| TRMT1L | MRPL44 | 0.672449 | 4 | 0 | 4 |
| TRMT1L | SLC22A15 | 0.67127 | 3 | 0 | 3 |
For details and further investigation, click here
