| Full name: synaptophysin like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q22.2 | ||
| Entrez ID: 6856 | HGNC ID: HGNC:11507 | Ensembl Gene: ENSG00000008282 | OMIM ID: 616665 |
| Drug and gene relationship at DGIdb | |||
Expression of SYPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYPL1 | 6856 | 201260_s_at | -0.1596 | 0.8264 | |
| GSE20347 | SYPL1 | 6856 | 201260_s_at | -0.1911 | 0.3040 | |
| GSE23400 | SYPL1 | 6856 | 201259_s_at | 0.0602 | 0.6571 | |
| GSE26886 | SYPL1 | 6856 | 201260_s_at | -0.5904 | 0.0052 | |
| GSE29001 | SYPL1 | 6856 | 201260_s_at | -0.1656 | 0.4071 | |
| GSE38129 | SYPL1 | 6856 | 201260_s_at | -0.0970 | 0.5420 | |
| GSE45670 | SYPL1 | 6856 | 201260_s_at | -0.0020 | 0.9914 | |
| GSE53622 | SYPL1 | 6856 | 32163 | -0.0665 | 0.5045 | |
| GSE53624 | SYPL1 | 6856 | 32163 | -0.2420 | 0.0008 | |
| GSE63941 | SYPL1 | 6856 | 201259_s_at | 1.2994 | 0.0132 | |
| GSE77861 | SYPL1 | 6856 | 201260_s_at | -0.2596 | 0.2195 | |
| GSE97050 | SYPL1 | 6856 | A_23_P93881 | 0.0110 | 0.9753 | |
| SRP007169 | SYPL1 | 6856 | RNAseq | -1.0201 | 0.0081 | |
| SRP008496 | SYPL1 | 6856 | RNAseq | -0.7637 | 0.0003 | |
| SRP064894 | SYPL1 | 6856 | RNAseq | -0.3468 | 0.0589 | |
| SRP133303 | SYPL1 | 6856 | RNAseq | -0.1851 | 0.4070 | |
| SRP159526 | SYPL1 | 6856 | RNAseq | -0.8914 | 0.0258 | |
| SRP193095 | SYPL1 | 6856 | RNAseq | -0.3849 | 0.0354 | |
| SRP219564 | SYPL1 | 6856 | RNAseq | -0.5731 | 0.0751 | |
| TCGA | SYPL1 | 6856 | RNAseq | 0.1053 | 0.0452 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by SYPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYPL1 | 6856 | 12 | 0 | 18 | |
| GSE20123 | SYPL1 | 6856 | 12 | 0 | 18 | |
| GSE43470 | SYPL1 | 6856 | 7 | 1 | 35 | |
| GSE46452 | SYPL1 | 6856 | 10 | 1 | 48 | |
| GSE47630 | SYPL1 | 6856 | 7 | 3 | 30 | |
| GSE54993 | SYPL1 | 6856 | 2 | 9 | 59 | |
| GSE54994 | SYPL1 | 6856 | 15 | 3 | 35 | |
| GSE60625 | SYPL1 | 6856 | 0 | 0 | 11 | |
| GSE74703 | SYPL1 | 6856 | 7 | 1 | 28 | |
| GSE74704 | SYPL1 | 6856 | 8 | 0 | 12 | |
| TCGA | SYPL1 | 6856 | 52 | 9 | 35 |
Total number of gains: 132; Total number of losses: 27; Total Number of normals: 329.
Somatic mutations of SYPL1:
Generating mutation plots.
Highly correlated genes for SYPL1:
Showing top 20/699 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYPL1 | RNF144B | 0.832892 | 3 | 0 | 3 |
| SYPL1 | BTRC | 0.809142 | 3 | 0 | 3 |
| SYPL1 | ARRDC3 | 0.774399 | 3 | 0 | 3 |
| SYPL1 | TET2 | 0.768 | 4 | 0 | 4 |
| SYPL1 | RCAN3 | 0.764846 | 3 | 0 | 3 |
| SYPL1 | YTHDF2 | 0.761565 | 3 | 0 | 3 |
| SYPL1 | ZNF398 | 0.75398 | 3 | 0 | 3 |
| SYPL1 | MIPEP | 0.749923 | 4 | 0 | 4 |
| SYPL1 | SPIN4 | 0.74988 | 3 | 0 | 3 |
| SYPL1 | TMEM127 | 0.749279 | 3 | 0 | 3 |
| SYPL1 | SMC2 | 0.748148 | 3 | 0 | 3 |
| SYPL1 | MNS1 | 0.747206 | 3 | 0 | 3 |
| SYPL1 | FBXL14 | 0.743151 | 3 | 0 | 3 |
| SYPL1 | PRKAR2A | 0.739998 | 4 | 0 | 4 |
| SYPL1 | SERTAD4 | 0.739541 | 3 | 0 | 3 |
| SYPL1 | UNC5CL | 0.735336 | 3 | 0 | 3 |
| SYPL1 | ZNF175 | 0.727749 | 3 | 0 | 3 |
| SYPL1 | CNOT6L | 0.72755 | 3 | 0 | 3 |
| SYPL1 | C4orf33 | 0.726783 | 4 | 0 | 4 |
| SYPL1 | FBXO8 | 0.726621 | 4 | 0 | 3 |
For details and further investigation, click here
