| Full name: ring finger and SPRY domain containing 1 | Alias Symbol: KIAA1972 | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 89970 | HGNC ID: HGNC:29420 | Ensembl Gene: ENSG00000159579 | OMIM ID: 616585 |
| Drug and gene relationship at DGIdb | |||
Expression of RSPRY1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RSPRY1 | 89970 | 225773_at | 0.1701 | 0.6439 | |
| GSE26886 | RSPRY1 | 89970 | 225773_at | -0.3497 | 0.0489 | |
| GSE45670 | RSPRY1 | 89970 | 225773_at | 0.0989 | 0.4520 | |
| GSE53622 | RSPRY1 | 89970 | 90526 | 0.2365 | 0.0000 | |
| GSE53624 | RSPRY1 | 89970 | 90526 | 0.2242 | 0.0002 | |
| GSE63941 | RSPRY1 | 89970 | 225770_at | 0.0720 | 0.8734 | |
| GSE77861 | RSPRY1 | 89970 | 225770_at | 0.1168 | 0.3216 | |
| GSE97050 | RSPRY1 | 89970 | A_33_P3327454 | 0.3099 | 0.2682 | |
| SRP007169 | RSPRY1 | 89970 | RNAseq | -0.0638 | 0.8328 | |
| SRP008496 | RSPRY1 | 89970 | RNAseq | -0.0639 | 0.7622 | |
| SRP064894 | RSPRY1 | 89970 | RNAseq | -0.0328 | 0.8673 | |
| SRP133303 | RSPRY1 | 89970 | RNAseq | 0.3837 | 0.0002 | |
| SRP159526 | RSPRY1 | 89970 | RNAseq | 0.0362 | 0.7742 | |
| SRP193095 | RSPRY1 | 89970 | RNAseq | -0.1114 | 0.1708 | |
| SRP219564 | RSPRY1 | 89970 | RNAseq | 0.0240 | 0.9562 | |
| TCGA | RSPRY1 | 89970 | RNAseq | -0.0812 | 0.1439 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RSPRY1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RSPRY1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RSPRY1 | 89970 | 6 | 0 | 24 | |
| GSE20123 | RSPRY1 | 89970 | 6 | 1 | 23 | |
| GSE43470 | RSPRY1 | 89970 | 3 | 6 | 34 | |
| GSE46452 | RSPRY1 | 89970 | 38 | 1 | 20 | |
| GSE47630 | RSPRY1 | 89970 | 10 | 8 | 22 | |
| GSE54993 | RSPRY1 | 89970 | 2 | 4 | 64 | |
| GSE54994 | RSPRY1 | 89970 | 7 | 10 | 36 | |
| GSE60625 | RSPRY1 | 89970 | 4 | 0 | 7 | |
| GSE74703 | RSPRY1 | 89970 | 3 | 3 | 30 | |
| GSE74704 | RSPRY1 | 89970 | 5 | 0 | 15 | |
| TCGA | RSPRY1 | 89970 | 25 | 13 | 58 |
Total number of gains: 109; Total number of losses: 46; Total Number of normals: 333.
Somatic mutations of RSPRY1:
Generating mutation plots.
Highly correlated genes for RSPRY1:
Showing top 20/263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RSPRY1 | GZF1 | 0.791007 | 3 | 0 | 3 |
| RSPRY1 | TCERG1 | 0.784075 | 3 | 0 | 3 |
| RSPRY1 | MBD1 | 0.770024 | 3 | 0 | 3 |
| RSPRY1 | CYLD | 0.754684 | 3 | 0 | 3 |
| RSPRY1 | TMCO6 | 0.748065 | 3 | 0 | 3 |
| RSPRY1 | PPP1R3D | 0.745619 | 3 | 0 | 3 |
| RSPRY1 | RASA1 | 0.743399 | 3 | 0 | 3 |
| RSPRY1 | RCOR1 | 0.743026 | 3 | 0 | 3 |
| RSPRY1 | TRAF7 | 0.739358 | 3 | 0 | 3 |
| RSPRY1 | AP1G1 | 0.733673 | 4 | 0 | 4 |
| RSPRY1 | JKAMP | 0.729518 | 3 | 0 | 3 |
| RSPRY1 | TRAPPC10 | 0.726146 | 3 | 0 | 3 |
| RSPRY1 | MCCC2 | 0.721637 | 3 | 0 | 3 |
| RSPRY1 | PIGL | 0.71512 | 3 | 0 | 3 |
| RSPRY1 | RAB22A | 0.715049 | 4 | 0 | 3 |
| RSPRY1 | TBC1D23 | 0.705303 | 3 | 0 | 3 |
| RSPRY1 | PIAS4 | 0.705226 | 3 | 0 | 3 |
| RSPRY1 | TPD52L2 | 0.701727 | 4 | 0 | 3 |
| RSPRY1 | ATP6V1A | 0.699465 | 3 | 0 | 3 |
| RSPRY1 | RBBP4 | 0.699117 | 3 | 0 | 3 |
For details and further investigation, click here
