| Full name: RAB21, member RAS oncogene family | Alias Symbol: KIAA0118 | ||
| Type: protein-coding gene | Cytoband: 12q21.1 | ||
| Entrez ID: 23011 | HGNC ID: HGNC:18263 | Ensembl Gene: ENSG00000080371 | OMIM ID: 612398 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB21 | 23011 | 203885_at | -0.1697 | 0.6710 | |
| GSE20347 | RAB21 | 23011 | 203885_at | -0.1855 | 0.2089 | |
| GSE23400 | RAB21 | 23011 | 203885_at | 0.0072 | 0.9445 | |
| GSE26886 | RAB21 | 23011 | 203885_at | -1.5497 | 0.0000 | |
| GSE29001 | RAB21 | 23011 | 203885_at | 0.0565 | 0.8276 | |
| GSE38129 | RAB21 | 23011 | 203885_at | -0.1270 | 0.3337 | |
| GSE45670 | RAB21 | 23011 | 203885_at | -0.0532 | 0.6514 | |
| GSE53622 | RAB21 | 23011 | 163566 | -0.1496 | 0.0087 | |
| GSE53624 | RAB21 | 23011 | 163566 | -0.0670 | 0.2778 | |
| GSE63941 | RAB21 | 23011 | 203885_at | -0.1990 | 0.6950 | |
| GSE77861 | RAB21 | 23011 | 203885_at | -0.0468 | 0.8889 | |
| GSE97050 | RAB21 | 23011 | A_23_P128166 | -0.1347 | 0.5436 | |
| SRP007169 | RAB21 | 23011 | RNAseq | -0.5390 | 0.1844 | |
| SRP008496 | RAB21 | 23011 | RNAseq | -0.3964 | 0.0641 | |
| SRP064894 | RAB21 | 23011 | RNAseq | -0.1780 | 0.3098 | |
| SRP133303 | RAB21 | 23011 | RNAseq | 0.2517 | 0.0921 | |
| SRP159526 | RAB21 | 23011 | RNAseq | 0.1017 | 0.7466 | |
| SRP193095 | RAB21 | 23011 | RNAseq | -0.0247 | 0.8246 | |
| SRP219564 | RAB21 | 23011 | RNAseq | -0.2584 | 0.2113 | |
| TCGA | RAB21 | 23011 | RNAseq | 0.0187 | 0.6976 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RAB21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB21 | 23011 | 4 | 3 | 23 | |
| GSE20123 | RAB21 | 23011 | 4 | 3 | 23 | |
| GSE43470 | RAB21 | 23011 | 3 | 0 | 40 | |
| GSE46452 | RAB21 | 23011 | 8 | 1 | 50 | |
| GSE47630 | RAB21 | 23011 | 10 | 1 | 29 | |
| GSE54993 | RAB21 | 23011 | 0 | 5 | 65 | |
| GSE54994 | RAB21 | 23011 | 8 | 1 | 44 | |
| GSE60625 | RAB21 | 23011 | 0 | 0 | 11 | |
| GSE74703 | RAB21 | 23011 | 3 | 0 | 33 | |
| GSE74704 | RAB21 | 23011 | 3 | 2 | 15 | |
| TCGA | RAB21 | 23011 | 22 | 8 | 66 |
Total number of gains: 65; Total number of losses: 24; Total Number of normals: 399.
Somatic mutations of RAB21:
Generating mutation plots.
Highly correlated genes for RAB21:
Showing top 20/465 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB21 | TRIP12 | 0.81719 | 4 | 0 | 4 |
| RAB21 | SLC35E3 | 0.779375 | 4 | 0 | 4 |
| RAB21 | SPAG16 | 0.776696 | 3 | 0 | 3 |
| RAB21 | QRICH1 | 0.764038 | 3 | 0 | 3 |
| RAB21 | IST1 | 0.750489 | 3 | 0 | 3 |
| RAB21 | EIF3I | 0.745266 | 3 | 0 | 3 |
| RAB21 | KLHL20 | 0.73991 | 3 | 0 | 3 |
| RAB21 | TMBIM4 | 0.734024 | 4 | 0 | 4 |
| RAB21 | CNOT4 | 0.732714 | 4 | 0 | 3 |
| RAB21 | CDIPT | 0.730006 | 3 | 0 | 3 |
| RAB21 | SERTAD1 | 0.729679 | 3 | 0 | 3 |
| RAB21 | UBA3 | 0.727361 | 4 | 0 | 3 |
| RAB21 | CCNYL1 | 0.723647 | 4 | 0 | 3 |
| RAB21 | NIT1 | 0.720876 | 3 | 0 | 3 |
| RAB21 | SCAPER | 0.716204 | 3 | 0 | 3 |
| RAB21 | GABPA | 0.715152 | 3 | 0 | 3 |
| RAB21 | MAT2B | 0.713963 | 4 | 0 | 3 |
| RAB21 | SNX6 | 0.712696 | 3 | 0 | 3 |
| RAB21 | FRMD4B | 0.712255 | 4 | 0 | 3 |
| RAB21 | RASA2 | 0.710615 | 3 | 0 | 3 |
For details and further investigation, click here
