| Full name: WD repeat domain 47 | Alias Symbol: KIAA0893 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 22911 | HGNC ID: HGNC:29141 | Ensembl Gene: ENSG00000085433 | OMIM ID: 615734 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR47:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR47 | 22911 | 203855_at | -0.6112 | 0.4266 | |
| GSE20347 | WDR47 | 22911 | 203855_at | -0.8234 | 0.0000 | |
| GSE23400 | WDR47 | 22911 | 203855_at | -0.2662 | 0.0048 | |
| GSE26886 | WDR47 | 22911 | 203855_at | -0.9436 | 0.0004 | |
| GSE29001 | WDR47 | 22911 | 203855_at | -0.7836 | 0.0090 | |
| GSE38129 | WDR47 | 22911 | 203855_at | -0.6517 | 0.0000 | |
| GSE45670 | WDR47 | 22911 | 203855_at | -0.4006 | 0.0374 | |
| GSE63941 | WDR47 | 22911 | 203855_at | -1.1215 | 0.1168 | |
| GSE77861 | WDR47 | 22911 | 203855_at | -0.1943 | 0.4250 | |
| GSE97050 | WDR47 | 22911 | A_23_P23748 | -0.2334 | 0.4238 | |
| SRP007169 | WDR47 | 22911 | RNAseq | -1.4919 | 0.0030 | |
| SRP008496 | WDR47 | 22911 | RNAseq | -1.5774 | 0.0000 | |
| SRP064894 | WDR47 | 22911 | RNAseq | -1.1925 | 0.0001 | |
| SRP133303 | WDR47 | 22911 | RNAseq | -0.4900 | 0.0160 | |
| SRP159526 | WDR47 | 22911 | RNAseq | -1.1618 | 0.0002 | |
| SRP193095 | WDR47 | 22911 | RNAseq | -0.8694 | 0.0000 | |
| SRP219564 | WDR47 | 22911 | RNAseq | -1.1647 | 0.0352 | |
| TCGA | WDR47 | 22911 | RNAseq | -0.0017 | 0.9811 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by WDR47 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of WDR47:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR47 | 22911 | 0 | 12 | 18 | |
| GSE20123 | WDR47 | 22911 | 0 | 11 | 19 | |
| GSE43470 | WDR47 | 22911 | 0 | 8 | 35 | |
| GSE46452 | WDR47 | 22911 | 2 | 1 | 56 | |
| GSE47630 | WDR47 | 22911 | 9 | 5 | 26 | |
| GSE54993 | WDR47 | 22911 | 0 | 1 | 69 | |
| GSE54994 | WDR47 | 22911 | 7 | 4 | 42 | |
| GSE60625 | WDR47 | 22911 | 0 | 0 | 11 | |
| GSE74703 | WDR47 | 22911 | 0 | 6 | 30 | |
| GSE74704 | WDR47 | 22911 | 0 | 7 | 13 | |
| TCGA | WDR47 | 22911 | 8 | 26 | 62 |
Total number of gains: 26; Total number of losses: 81; Total Number of normals: 381.
Somatic mutations of WDR47:
Generating mutation plots.
Highly correlated genes for WDR47:
Showing top 20/932 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR47 | CERS4 | 0.78285 | 3 | 0 | 3 |
| WDR47 | CHCHD1 | 0.754187 | 3 | 0 | 3 |
| WDR47 | PRADC1 | 0.74269 | 3 | 0 | 3 |
| WDR47 | ZNF268 | 0.741005 | 3 | 0 | 3 |
| WDR47 | ACTR2 | 0.740996 | 3 | 0 | 3 |
| WDR47 | TRMT1L | 0.73729 | 3 | 0 | 3 |
| WDR47 | TBCK | 0.732445 | 3 | 0 | 3 |
| WDR47 | GOLGA4 | 0.726516 | 6 | 0 | 6 |
| WDR47 | ZNF416 | 0.722314 | 3 | 0 | 3 |
| WDR47 | VPS25 | 0.713252 | 4 | 0 | 4 |
| WDR47 | NAPG | 0.709121 | 3 | 0 | 3 |
| WDR47 | LRRC40 | 0.707843 | 4 | 0 | 3 |
| WDR47 | REEP3 | 0.707027 | 3 | 0 | 3 |
| WDR47 | EIF4ENIF1 | 0.705985 | 3 | 0 | 3 |
| WDR47 | CERS3 | 0.705479 | 4 | 0 | 4 |
| WDR47 | RAB18 | 0.704956 | 4 | 0 | 4 |
| WDR47 | A2ML1 | 0.702952 | 3 | 0 | 3 |
| WDR47 | IPO7 | 0.702914 | 3 | 0 | 3 |
| WDR47 | CTTNBP2NL | 0.702321 | 7 | 0 | 6 |
| WDR47 | FAM126B | 0.701847 | 3 | 0 | 3 |
For details and further investigation, click here
