| Full name: tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | Alias Symbol: FLJ10140|MTO2 | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 55687 | HGNC ID: HGNC:25481 | Ensembl Gene: ENSG00000100416 | OMIM ID: 610230 |
| Drug and gene relationship at DGIdb | |||
Expression of TRMU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMU | 55687 | 213634_s_at | 0.2960 | 0.3813 | |
| GSE20347 | TRMU | 55687 | 213634_s_at | 0.0394 | 0.6851 | |
| GSE23400 | TRMU | 55687 | 213634_s_at | -0.0381 | 0.3058 | |
| GSE26886 | TRMU | 55687 | 213634_s_at | 0.0908 | 0.6248 | |
| GSE29001 | TRMU | 55687 | 213634_s_at | 0.0415 | 0.8188 | |
| GSE38129 | TRMU | 55687 | 213634_s_at | 0.0175 | 0.8462 | |
| GSE45670 | TRMU | 55687 | 213634_s_at | 0.0948 | 0.2914 | |
| GSE53622 | TRMU | 55687 | 10311 | 0.3454 | 0.0000 | |
| GSE53624 | TRMU | 55687 | 10311 | 0.1525 | 0.0315 | |
| GSE63941 | TRMU | 55687 | 213634_s_at | -0.1920 | 0.6077 | |
| GSE77861 | TRMU | 55687 | 213634_s_at | -0.0313 | 0.8771 | |
| GSE97050 | TRMU | 55687 | A_33_P3433156 | 0.2965 | 0.2628 | |
| SRP007169 | TRMU | 55687 | RNAseq | 0.1122 | 0.7927 | |
| SRP008496 | TRMU | 55687 | RNAseq | -0.3253 | 0.2990 | |
| SRP064894 | TRMU | 55687 | RNAseq | 0.6628 | 0.0010 | |
| SRP133303 | TRMU | 55687 | RNAseq | 0.1484 | 0.2469 | |
| SRP159526 | TRMU | 55687 | RNAseq | 0.4142 | 0.1344 | |
| SRP193095 | TRMU | 55687 | RNAseq | 0.2582 | 0.0137 | |
| SRP219564 | TRMU | 55687 | RNAseq | 0.2735 | 0.4891 | |
| TCGA | TRMU | 55687 | RNAseq | 0.0734 | 0.2447 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRMU expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRMU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMU | 55687 | 5 | 6 | 19 | |
| GSE20123 | TRMU | 55687 | 4 | 5 | 21 | |
| GSE43470 | TRMU | 55687 | 2 | 6 | 35 | |
| GSE46452 | TRMU | 55687 | 31 | 2 | 26 | |
| GSE47630 | TRMU | 55687 | 9 | 4 | 27 | |
| GSE54993 | TRMU | 55687 | 3 | 6 | 61 | |
| GSE54994 | TRMU | 55687 | 11 | 7 | 35 | |
| GSE60625 | TRMU | 55687 | 5 | 0 | 6 | |
| GSE74703 | TRMU | 55687 | 2 | 4 | 30 | |
| GSE74704 | TRMU | 55687 | 2 | 3 | 15 | |
| TCGA | TRMU | 55687 | 28 | 15 | 53 |
Total number of gains: 102; Total number of losses: 58; Total Number of normals: 328.
Somatic mutations of TRMU:
Generating mutation plots.
Highly correlated genes for TRMU:
Showing top 20/320 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMU | ZNF584 | 0.766249 | 3 | 0 | 3 |
| TRMU | WIZ | 0.764873 | 3 | 0 | 3 |
| TRMU | NSD1 | 0.756013 | 3 | 0 | 3 |
| TRMU | ACAD9 | 0.750606 | 3 | 0 | 3 |
| TRMU | AGK | 0.726191 | 3 | 0 | 3 |
| TRMU | ABCF1 | 0.717026 | 4 | 0 | 4 |
| TRMU | WDR4 | 0.714818 | 3 | 0 | 3 |
| TRMU | ZNF766 | 0.713899 | 3 | 0 | 3 |
| TRMU | CWF19L1 | 0.710854 | 3 | 0 | 3 |
| TRMU | CHAF1B | 0.709481 | 3 | 0 | 3 |
| TRMU | TMSB4Y | 0.707115 | 3 | 0 | 3 |
| TRMU | KHSRP | 0.70484 | 3 | 0 | 3 |
| TRMU | SLC39A3 | 0.703485 | 3 | 0 | 3 |
| TRMU | FKBPL | 0.702406 | 3 | 0 | 3 |
| TRMU | PDRG1 | 0.701975 | 3 | 0 | 3 |
| TRMU | HAVCR2 | 0.701635 | 3 | 0 | 3 |
| TRMU | ZNF79 | 0.70155 | 3 | 0 | 3 |
| TRMU | NCOA6 | 0.693894 | 3 | 0 | 3 |
| TRMU | KPNA1 | 0.690462 | 3 | 0 | 3 |
| TRMU | LRRC42 | 0.686122 | 3 | 0 | 3 |
For details and further investigation, click here
