LRRC42

 

Full name: leucine rich repeat containing 42 Alias Symbol: MGC8974
Type: protein-coding gene Cytoband: 1p32.3
Entrez ID: 115353 HGNC ID: HGNC:28792 Ensembl Gene: ENSG00000116212 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of LRRC42:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LRRC42 115353 215084_s_at 0.4946 0.3293
GSE20347 LRRC42 115353 215084_s_at 0.2803 0.1708
GSE23400 LRRC42 115353 215084_s_at 0.3317 0.0000
GSE26886 LRRC42 115353 215084_s_at 0.3619 0.0898
GSE29001 LRRC42 115353 215084_s_at 0.5000 0.1168
GSE38129 LRRC42 115353 215084_s_at 0.5087 0.0018
GSE45670 LRRC42 115353 215084_s_at 0.2165 0.1723
GSE53622 LRRC42 115353 99664 0.7735 0.0000
GSE53624 LRRC42 115353 99664 0.7303 0.0000
GSE63941 LRRC42 115353 215084_s_at -0.4302 0.2311
GSE77861 LRRC42 115353 215084_s_at 0.1410 0.6501
GSE97050 LRRC42 115353 A_24_P276791 0.7503 0.1227
SRP007169 LRRC42 115353 RNAseq 1.0953 0.0100
SRP008496 LRRC42 115353 RNAseq 0.9587 0.0012
SRP064894 LRRC42 115353 RNAseq 0.5855 0.0018
SRP133303 LRRC42 115353 RNAseq 0.6737 0.0007
SRP159526 LRRC42 115353 RNAseq 0.5352 0.2637
SRP193095 LRRC42 115353 RNAseq 0.4170 0.0004
SRP219564 LRRC42 115353 RNAseq 0.2689 0.4032
TCGA LRRC42 115353 RNAseq 0.2231 0.0001

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by LRRC42 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LRRC42:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LRRC42 115353 3 4 23
GSE20123 LRRC42 115353 3 3 24
GSE43470 LRRC42 115353 6 2 35
GSE46452 LRRC42 115353 2 1 56
GSE47630 LRRC42 115353 8 4 28
GSE54993 LRRC42 115353 0 0 70
GSE54994 LRRC42 115353 10 2 41
GSE60625 LRRC42 115353 0 0 11
GSE74703 LRRC42 115353 4 1 31
GSE74704 LRRC42 115353 2 0 18
TCGA LRRC42 115353 10 18 68

Total number of gains: 48; Total number of losses: 35; Total Number of normals: 405.  

 

Somatic mutations of LRRC42:

 

Generating mutation plots.

 

Highly correlated genes for LRRC42:

 

Showing top 20/1508 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LRRC42TRUB10.810972303
LRRC42XPO40.784285303
LRRC42MTHFD1L0.772993303
LRRC42MICALCL0.767542303
LRRC42POLDIP30.761149303
LRRC42ATG4C0.742355303
LRRC42MAD2L20.739219606
LRRC42COMMD50.7371303
LRRC42SCNM10.718651303
LRRC42BMP20.716796303
LRRC42TMEM2370.715869303
LRRC42EARS20.715201403
LRRC42SDC40.714166404
LRRC42MORN20.711917303
LRRC42SASS60.711629504
LRRC42SLC35B20.711044303
LRRC42KTI120.708412403
LRRC42TMEM440.706013404
LRRC42TMEM540.703902303
LRRC42CTU20.702411505

For details and further investigation, click here