| Full name: FKBP prolyl isomerase like | Alias Symbol: DIR1|NG7|WISp39 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 63943 | HGNC ID: HGNC:13949 | Ensembl Gene: ENSG00000204315 | OMIM ID: 617076 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FKBPL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKBPL | 63943 | 219187_at | 0.2949 | 0.6867 | |
| GSE20347 | FKBPL | 63943 | 219187_at | -0.4497 | 0.0000 | |
| GSE23400 | FKBPL | 63943 | 219187_at | -0.2227 | 0.0006 | |
| GSE26886 | FKBPL | 63943 | 219187_at | -0.6823 | 0.0007 | |
| GSE29001 | FKBPL | 63943 | 219187_at | -0.2050 | 0.1684 | |
| GSE38129 | FKBPL | 63943 | 219187_at | -0.0986 | 0.4510 | |
| GSE45670 | FKBPL | 63943 | 219187_at | -0.1084 | 0.4048 | |
| GSE53622 | FKBPL | 63943 | 28961 | -0.8044 | 0.0001 | |
| GSE53624 | FKBPL | 63943 | 28961 | -0.7362 | 0.0000 | |
| GSE63941 | FKBPL | 63943 | 219187_at | 0.7601 | 0.0164 | |
| GSE77861 | FKBPL | 63943 | 219187_at | -0.2942 | 0.1010 | |
| GSE97050 | FKBPL | 63943 | A_23_P70566 | -0.0101 | 0.9672 | |
| SRP007169 | FKBPL | 63943 | RNAseq | -1.9494 | 0.0000 | |
| SRP008496 | FKBPL | 63943 | RNAseq | -1.9484 | 0.0000 | |
| SRP064894 | FKBPL | 63943 | RNAseq | -0.2521 | 0.4148 | |
| SRP133303 | FKBPL | 63943 | RNAseq | -0.6756 | 0.0001 | |
| SRP159526 | FKBPL | 63943 | RNAseq | -0.9110 | 0.0002 | |
| SRP193095 | FKBPL | 63943 | RNAseq | -0.8215 | 0.0000 | |
| SRP219564 | FKBPL | 63943 | RNAseq | -0.6073 | 0.2887 | |
| TCGA | FKBPL | 63943 | RNAseq | 0.0992 | 0.3218 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FKBPL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKBPL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKBPL | 63943 | 5 | 1 | 24 | |
| GSE20123 | FKBPL | 63943 | 5 | 1 | 24 | |
| GSE43470 | FKBPL | 63943 | 5 | 1 | 37 | |
| GSE46452 | FKBPL | 63943 | 1 | 10 | 48 | |
| GSE47630 | FKBPL | 63943 | 7 | 4 | 29 | |
| GSE54993 | FKBPL | 63943 | 2 | 1 | 67 | |
| GSE54994 | FKBPL | 63943 | 11 | 4 | 38 | |
| GSE60625 | FKBPL | 63943 | 0 | 1 | 10 | |
| GSE74703 | FKBPL | 63943 | 5 | 0 | 31 | |
| GSE74704 | FKBPL | 63943 | 2 | 0 | 18 | |
| TCGA | FKBPL | 63943 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of FKBPL:
Generating mutation plots.
Highly correlated genes for FKBPL:
Showing top 20/1129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKBPL | FCF1 | 0.797961 | 3 | 0 | 3 |
| FKBPL | TMEM54 | 0.777185 | 3 | 0 | 3 |
| FKBPL | PPT2 | 0.766053 | 3 | 0 | 3 |
| FKBPL | ALKBH7 | 0.765365 | 4 | 0 | 4 |
| FKBPL | MORN2 | 0.729212 | 3 | 0 | 3 |
| FKBPL | PET100 | 0.721082 | 3 | 0 | 3 |
| FKBPL | ACTR2 | 0.720481 | 3 | 0 | 3 |
| FKBPL | TRIAP1 | 0.720057 | 4 | 0 | 4 |
| FKBPL | FOXP4 | 0.717733 | 3 | 0 | 3 |
| FKBPL | TMEM167A | 0.715913 | 3 | 0 | 3 |
| FKBPL | GLE1 | 0.713994 | 3 | 0 | 3 |
| FKBPL | PDIK1L | 0.713015 | 4 | 0 | 4 |
| FKBPL | GAR1 | 0.712856 | 4 | 0 | 4 |
| FKBPL | GPR108 | 0.712374 | 3 | 0 | 3 |
| FKBPL | STK11IP | 0.706872 | 3 | 0 | 3 |
| FKBPL | PPP1R37 | 0.705789 | 4 | 0 | 4 |
| FKBPL | CIB1 | 0.705599 | 3 | 0 | 3 |
| FKBPL | TMCO6 | 0.704375 | 3 | 0 | 3 |
| FKBPL | TRMU | 0.702406 | 3 | 0 | 3 |
| FKBPL | DHRS4L2 | 0.702236 | 3 | 0 | 3 |
For details and further investigation, click here
