| Full name: p53 and DNA damage regulated 1 | Alias Symbol: dJ310O13.3 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 81572 | HGNC ID: HGNC:16119 | Ensembl Gene: ENSG00000088356 | OMIM ID: 610789 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PDRG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDRG1 | 81572 | 225075_at | 0.9291 | 0.0460 | |
| GSE26886 | PDRG1 | 81572 | 225075_at | -0.0708 | 0.7554 | |
| GSE45670 | PDRG1 | 81572 | 225075_at | 0.3447 | 0.0456 | |
| GSE53622 | PDRG1 | 81572 | 55903 | 0.5180 | 0.0000 | |
| GSE53624 | PDRG1 | 81572 | 55903 | 0.6129 | 0.0000 | |
| GSE63941 | PDRG1 | 81572 | 225075_at | 0.6063 | 0.1116 | |
| GSE77861 | PDRG1 | 81572 | 225075_at | 0.3277 | 0.1702 | |
| GSE97050 | PDRG1 | 81572 | A_23_P166159 | 0.3459 | 0.4664 | |
| SRP007169 | PDRG1 | 81572 | RNAseq | 0.2619 | 0.4674 | |
| SRP008496 | PDRG1 | 81572 | RNAseq | 0.3559 | 0.1963 | |
| SRP064894 | PDRG1 | 81572 | RNAseq | 0.9181 | 0.0005 | |
| SRP133303 | PDRG1 | 81572 | RNAseq | 0.4438 | 0.0096 | |
| SRP159526 | PDRG1 | 81572 | RNAseq | 0.4343 | 0.0994 | |
| SRP193095 | PDRG1 | 81572 | RNAseq | -0.0027 | 0.9846 | |
| SRP219564 | PDRG1 | 81572 | RNAseq | 0.2981 | 0.4242 | |
| TCGA | PDRG1 | 81572 | RNAseq | 0.1704 | 0.0080 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDRG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDRG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDRG1 | 81572 | 15 | 0 | 15 | |
| GSE20123 | PDRG1 | 81572 | 15 | 0 | 15 | |
| GSE43470 | PDRG1 | 81572 | 11 | 0 | 32 | |
| GSE46452 | PDRG1 | 81572 | 29 | 0 | 30 | |
| GSE47630 | PDRG1 | 81572 | 25 | 0 | 15 | |
| GSE54993 | PDRG1 | 81572 | 0 | 18 | 52 | |
| GSE54994 | PDRG1 | 81572 | 27 | 1 | 25 | |
| GSE60625 | PDRG1 | 81572 | 0 | 0 | 11 | |
| GSE74703 | PDRG1 | 81572 | 10 | 0 | 26 | |
| GSE74704 | PDRG1 | 81572 | 10 | 0 | 10 | |
| TCGA | PDRG1 | 81572 | 49 | 1 | 46 |
Total number of gains: 191; Total number of losses: 20; Total Number of normals: 277.
Somatic mutations of PDRG1:
Generating mutation plots.
Highly correlated genes for PDRG1:
Showing top 20/880 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDRG1 | ISY1 | 0.789283 | 3 | 0 | 3 |
| PDRG1 | LRRC58 | 0.776453 | 3 | 0 | 3 |
| PDRG1 | USP36 | 0.773071 | 3 | 0 | 3 |
| PDRG1 | SLC35C2 | 0.771133 | 4 | 0 | 4 |
| PDRG1 | SRRT | 0.770225 | 3 | 0 | 3 |
| PDRG1 | CHD4 | 0.766327 | 3 | 0 | 3 |
| PDRG1 | TFDP2 | 0.761835 | 3 | 0 | 3 |
| PDRG1 | U2SURP | 0.758318 | 3 | 0 | 3 |
| PDRG1 | ARFRP1 | 0.757266 | 3 | 0 | 3 |
| PDRG1 | ABCF1 | 0.756573 | 4 | 0 | 4 |
| PDRG1 | ZNF318 | 0.756211 | 3 | 0 | 3 |
| PDRG1 | DHX33 | 0.745859 | 4 | 0 | 4 |
| PDRG1 | MMS19 | 0.741242 | 3 | 0 | 3 |
| PDRG1 | CDK5RAP1 | 0.729793 | 6 | 0 | 5 |
| PDRG1 | GOSR1 | 0.72468 | 3 | 0 | 3 |
| PDRG1 | CCDC150 | 0.723804 | 3 | 0 | 3 |
| PDRG1 | MKRN1 | 0.72135 | 3 | 0 | 3 |
| PDRG1 | KIF3B | 0.720237 | 7 | 0 | 6 |
| PDRG1 | UBE2O | 0.71903 | 4 | 0 | 4 |
| PDRG1 | TAF11 | 0.71841 | 3 | 0 | 3 |
For details and further investigation, click here
