| Full name: tetratricopeptide repeat domain 27 | Alias Symbol: FLJ20272 | ||
| Type: protein-coding gene | Cytoband: 2p22.3 | ||
| Entrez ID: 55622 | HGNC ID: HGNC:25986 | Ensembl Gene: ENSG00000018699 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC27 | 55622 | 218710_at | 0.2431 | 0.6778 | |
| GSE20347 | TTC27 | 55622 | 218710_at | 0.2215 | 0.2664 | |
| GSE23400 | TTC27 | 55622 | 218710_at | 0.3004 | 0.0000 | |
| GSE26886 | TTC27 | 55622 | 218710_at | 0.4954 | 0.0408 | |
| GSE29001 | TTC27 | 55622 | 218710_at | 0.2131 | 0.6112 | |
| GSE38129 | TTC27 | 55622 | 218710_at | 0.2365 | 0.0844 | |
| GSE45670 | TTC27 | 55622 | 218710_at | 0.0746 | 0.6849 | |
| GSE53622 | TTC27 | 55622 | 97563 | 0.1746 | 0.0190 | |
| GSE53624 | TTC27 | 55622 | 97563 | 0.2149 | 0.0024 | |
| GSE63941 | TTC27 | 55622 | 218710_at | 0.1910 | 0.7201 | |
| GSE77861 | TTC27 | 55622 | 218710_at | 0.2165 | 0.3039 | |
| GSE97050 | TTC27 | 55622 | A_23_P131227 | 0.2473 | 0.3542 | |
| SRP007169 | TTC27 | 55622 | RNAseq | 0.1934 | 0.5827 | |
| SRP008496 | TTC27 | 55622 | RNAseq | 0.1988 | 0.3984 | |
| SRP064894 | TTC27 | 55622 | RNAseq | 0.0663 | 0.6452 | |
| SRP133303 | TTC27 | 55622 | RNAseq | 0.2018 | 0.1546 | |
| SRP159526 | TTC27 | 55622 | RNAseq | 0.0866 | 0.7060 | |
| SRP193095 | TTC27 | 55622 | RNAseq | 0.1078 | 0.3096 | |
| SRP219564 | TTC27 | 55622 | RNAseq | -0.0020 | 0.9930 | |
| TCGA | TTC27 | 55622 | RNAseq | 0.1474 | 0.0112 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC27 | 55622 | 10 | 1 | 19 | |
| GSE20123 | TTC27 | 55622 | 9 | 1 | 20 | |
| GSE43470 | TTC27 | 55622 | 2 | 1 | 40 | |
| GSE46452 | TTC27 | 55622 | 2 | 4 | 53 | |
| GSE47630 | TTC27 | 55622 | 8 | 0 | 32 | |
| GSE54993 | TTC27 | 55622 | 0 | 5 | 65 | |
| GSE54994 | TTC27 | 55622 | 10 | 0 | 43 | |
| GSE60625 | TTC27 | 55622 | 0 | 3 | 8 | |
| GSE74703 | TTC27 | 55622 | 2 | 0 | 34 | |
| GSE74704 | TTC27 | 55622 | 9 | 1 | 10 | |
| TCGA | TTC27 | 55622 | 36 | 3 | 57 |
Total number of gains: 88; Total number of losses: 19; Total Number of normals: 381.
Somatic mutations of TTC27:
Generating mutation plots.
Highly correlated genes for TTC27:
Showing top 20/1041 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC27 | DUSP18 | 0.787161 | 3 | 0 | 3 |
| TTC27 | MORN2 | 0.745099 | 3 | 0 | 3 |
| TTC27 | RNF26 | 0.726657 | 3 | 0 | 3 |
| TTC27 | SMAD3 | 0.716514 | 3 | 0 | 3 |
| TTC27 | ARFGEF2 | 0.715265 | 3 | 0 | 3 |
| TTC27 | ZNF70 | 0.696074 | 3 | 0 | 3 |
| TTC27 | DNMBP | 0.69384 | 3 | 0 | 3 |
| TTC27 | SNX6 | 0.68953 | 3 | 0 | 3 |
| TTC27 | LRRC57 | 0.689196 | 3 | 0 | 3 |
| TTC27 | MRPL37 | 0.688675 | 4 | 0 | 3 |
| TTC27 | MTFMT | 0.686169 | 3 | 0 | 3 |
| TTC27 | C9orf64 | 0.684249 | 3 | 0 | 3 |
| TTC27 | FARSB | 0.682482 | 4 | 0 | 4 |
| TTC27 | TMEM60 | 0.681488 | 6 | 0 | 5 |
| TTC27 | JAG1 | 0.680223 | 4 | 0 | 3 |
| TTC27 | MST1R | 0.676934 | 3 | 0 | 3 |
| TTC27 | GSR | 0.67616 | 4 | 0 | 4 |
| TTC27 | MIS18BP1 | 0.675554 | 4 | 0 | 3 |
| TTC27 | STOML1 | 0.663891 | 3 | 0 | 3 |
| TTC27 | RPL26L1 | 0.656887 | 8 | 0 | 7 |
For details and further investigation, click here
