| Full name: dynamin binding protein | Alias Symbol: KIAA1010|Tuba|ARHGEF36 | ||
| Type: protein-coding gene | Cytoband: 10q24.2 | ||
| Entrez ID: 23268 | HGNC ID: HGNC:30373 | Ensembl Gene: ENSG00000107554 | OMIM ID: 611282 |
| Drug and gene relationship at DGIdb | |||
Expression of DNMBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNMBP | 23268 | 212838_at | -0.2150 | 0.7944 | |
| GSE20347 | DNMBP | 23268 | 212838_at | -0.0546 | 0.8020 | |
| GSE23400 | DNMBP | 23268 | 212838_at | -0.0202 | 0.7660 | |
| GSE26886 | DNMBP | 23268 | 212838_at | 0.1663 | 0.5273 | |
| GSE29001 | DNMBP | 23268 | 212838_at | -0.0478 | 0.8733 | |
| GSE38129 | DNMBP | 23268 | 212838_at | -0.1776 | 0.2404 | |
| GSE45670 | DNMBP | 23268 | 212838_at | 0.0197 | 0.9349 | |
| GSE53622 | DNMBP | 23268 | 80267 | -0.0092 | 0.9393 | |
| GSE53624 | DNMBP | 23268 | 80267 | 0.0060 | 0.9424 | |
| GSE63941 | DNMBP | 23268 | 212838_at | -0.5348 | 0.3173 | |
| GSE77861 | DNMBP | 23268 | 212838_at | 0.5411 | 0.0278 | |
| GSE97050 | DNMBP | 23268 | A_23_P328206 | -0.1037 | 0.6668 | |
| SRP007169 | DNMBP | 23268 | RNAseq | 0.3011 | 0.4399 | |
| SRP008496 | DNMBP | 23268 | RNAseq | 0.4049 | 0.2477 | |
| SRP064894 | DNMBP | 23268 | RNAseq | -0.2466 | 0.3800 | |
| SRP133303 | DNMBP | 23268 | RNAseq | -0.0916 | 0.5961 | |
| SRP159526 | DNMBP | 23268 | RNAseq | -0.1024 | 0.8352 | |
| SRP193095 | DNMBP | 23268 | RNAseq | -0.0923 | 0.6980 | |
| SRP219564 | DNMBP | 23268 | RNAseq | -0.0270 | 0.9247 | |
| TCGA | DNMBP | 23268 | RNAseq | -0.3801 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNMBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNMBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNMBP | 23268 | 1 | 8 | 21 | |
| GSE20123 | DNMBP | 23268 | 1 | 7 | 22 | |
| GSE43470 | DNMBP | 23268 | 0 | 7 | 36 | |
| GSE46452 | DNMBP | 23268 | 0 | 11 | 48 | |
| GSE47630 | DNMBP | 23268 | 2 | 14 | 24 | |
| GSE54993 | DNMBP | 23268 | 8 | 0 | 62 | |
| GSE54994 | DNMBP | 23268 | 1 | 12 | 40 | |
| GSE60625 | DNMBP | 23268 | 0 | 0 | 11 | |
| GSE74703 | DNMBP | 23268 | 0 | 5 | 31 | |
| GSE74704 | DNMBP | 23268 | 0 | 4 | 16 | |
| TCGA | DNMBP | 23268 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.
Somatic mutations of DNMBP:
Generating mutation plots.
Highly correlated genes for DNMBP:
Showing top 20/119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNMBP | ATIC | 0.844254 | 3 | 0 | 3 |
| DNMBP | YLPM1 | 0.796608 | 3 | 0 | 3 |
| DNMBP | NUP205 | 0.789578 | 3 | 0 | 3 |
| DNMBP | CD109 | 0.781191 | 3 | 0 | 3 |
| DNMBP | CHCHD2 | 0.768263 | 3 | 0 | 3 |
| DNMBP | DYNC2H1 | 0.766088 | 3 | 0 | 3 |
| DNMBP | ELP3 | 0.763227 | 3 | 0 | 3 |
| DNMBP | SPRED2 | 0.757587 | 4 | 0 | 4 |
| DNMBP | DTYMK | 0.752851 | 3 | 0 | 3 |
| DNMBP | IPO7 | 0.749915 | 3 | 0 | 3 |
| DNMBP | PJA1 | 0.746535 | 3 | 0 | 3 |
| DNMBP | AIFM1 | 0.746238 | 3 | 0 | 3 |
| DNMBP | SMCR8 | 0.744369 | 3 | 0 | 3 |
| DNMBP | KLHL7 | 0.742885 | 3 | 0 | 3 |
| DNMBP | CPSF3 | 0.738862 | 3 | 0 | 3 |
| DNMBP | TRAF7 | 0.733336 | 3 | 0 | 3 |
| DNMBP | FBXO39 | 0.732807 | 3 | 0 | 3 |
| DNMBP | PHKG2 | 0.731744 | 3 | 0 | 3 |
| DNMBP | AQR | 0.731145 | 3 | 0 | 3 |
| DNMBP | LRRC8A | 0.729155 | 3 | 0 | 3 |
For details and further investigation, click here
