| Full name: phenylalanyl-tRNA synthetase subunit beta | Alias Symbol: PheHB|FRSB | ||
| Type: protein-coding gene | Cytoband: 2q36.1 | ||
| Entrez ID: 10056 | HGNC ID: HGNC:17800 | Ensembl Gene: ENSG00000116120 | OMIM ID: 609690 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FARSB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FARSB | 10056 | 223035_s_at | -0.1305 | 0.8034 | |
| GSE26886 | FARSB | 10056 | 223035_s_at | -0.2586 | 0.1101 | |
| GSE45670 | FARSB | 10056 | 223035_s_at | -0.0189 | 0.9242 | |
| GSE53622 | FARSB | 10056 | 38701 | -0.0322 | 0.6421 | |
| GSE53624 | FARSB | 10056 | 38701 | -0.0448 | 0.4567 | |
| GSE63941 | FARSB | 10056 | 223035_s_at | 0.6708 | 0.1061 | |
| GSE77861 | FARSB | 10056 | 223035_s_at | -0.0066 | 0.9802 | |
| GSE97050 | FARSB | 10056 | A_23_P165355 | 0.3853 | 0.3259 | |
| SRP007169 | FARSB | 10056 | RNAseq | -0.6489 | 0.1293 | |
| SRP008496 | FARSB | 10056 | RNAseq | -0.3734 | 0.1295 | |
| SRP064894 | FARSB | 10056 | RNAseq | -0.0381 | 0.8105 | |
| SRP133303 | FARSB | 10056 | RNAseq | 0.0278 | 0.8586 | |
| SRP159526 | FARSB | 10056 | RNAseq | 0.0770 | 0.7015 | |
| SRP193095 | FARSB | 10056 | RNAseq | -0.3697 | 0.0009 | |
| SRP219564 | FARSB | 10056 | RNAseq | -0.0928 | 0.6639 | |
| TCGA | FARSB | 10056 | RNAseq | 0.1131 | 0.0238 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FARSB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FARSB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FARSB | 10056 | 2 | 13 | 15 | |
| GSE20123 | FARSB | 10056 | 2 | 13 | 15 | |
| GSE43470 | FARSB | 10056 | 0 | 7 | 36 | |
| GSE46452 | FARSB | 10056 | 0 | 5 | 54 | |
| GSE47630 | FARSB | 10056 | 4 | 5 | 31 | |
| GSE54993 | FARSB | 10056 | 1 | 2 | 67 | |
| GSE54994 | FARSB | 10056 | 8 | 10 | 35 | |
| GSE60625 | FARSB | 10056 | 3 | 0 | 8 | |
| GSE74703 | FARSB | 10056 | 0 | 6 | 30 | |
| GSE74704 | FARSB | 10056 | 2 | 7 | 11 | |
| TCGA | FARSB | 10056 | 13 | 27 | 56 |
Total number of gains: 35; Total number of losses: 95; Total Number of normals: 358.
Somatic mutations of FARSB:
Generating mutation plots.
Highly correlated genes for FARSB:
Showing top 20/95 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FARSB | NAGS | 0.694609 | 3 | 0 | 3 |
| FARSB | GLRX3 | 0.68798 | 4 | 0 | 4 |
| FARSB | TTC27 | 0.682482 | 4 | 0 | 4 |
| FARSB | ZW10 | 0.675084 | 3 | 0 | 3 |
| FARSB | ASL | 0.661755 | 3 | 0 | 3 |
| FARSB | CIAPIN1 | 0.661267 | 3 | 0 | 3 |
| FARSB | FAM83A | 0.642874 | 3 | 0 | 3 |
| FARSB | NDOR1 | 0.631953 | 3 | 0 | 3 |
| FARSB | EIF3I | 0.62737 | 5 | 0 | 4 |
| FARSB | VSNL1 | 0.621997 | 4 | 0 | 3 |
| FARSB | SDC4 | 0.62176 | 3 | 0 | 3 |
| FARSB | C16orf70 | 0.619956 | 4 | 0 | 3 |
| FARSB | NOL11 | 0.61935 | 3 | 0 | 3 |
| FARSB | IRAK2 | 0.612505 | 3 | 0 | 3 |
| FARSB | DHCR24 | 0.607651 | 3 | 0 | 3 |
| FARSB | SERINC2 | 0.606941 | 3 | 0 | 3 |
| FARSB | RPP40 | 0.606322 | 3 | 0 | 3 |
| FARSB | RLF | 0.605394 | 4 | 0 | 3 |
| FARSB | ZFC3H1 | 0.604704 | 3 | 0 | 3 |
| FARSB | MRPL49 | 0.603996 | 3 | 0 | 3 |
For details and further investigation, click here
