| Full name: tubulin alpha like 3 | Alias Symbol: FLJ21665 | ||
| Type: protein-coding gene | Cytoband: 10p15.1 | ||
| Entrez ID: 79861 | HGNC ID: HGNC:23534 | Ensembl Gene: ENSG00000178462 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
TUBAL3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04210 | Apoptosis | |
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBAL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBAL3 | 79861 | 220310_at | 0.8884 | 0.2698 | |
| GSE20347 | TUBAL3 | 79861 | 220310_at | 0.2441 | 0.0108 | |
| GSE23400 | TUBAL3 | 79861 | 220310_at | 0.0628 | 0.0475 | |
| GSE26886 | TUBAL3 | 79861 | 220310_at | 0.6835 | 0.0004 | |
| GSE29001 | TUBAL3 | 79861 | 220310_at | 0.3349 | 0.1732 | |
| GSE38129 | TUBAL3 | 79861 | 220310_at | 0.1893 | 0.0209 | |
| GSE45670 | TUBAL3 | 79861 | 220310_at | 0.0911 | 0.6807 | |
| GSE53622 | TUBAL3 | 79861 | 7966 | -0.0198 | 0.8099 | |
| GSE53624 | TUBAL3 | 79861 | 7966 | -0.1673 | 0.0468 | |
| GSE63941 | TUBAL3 | 79861 | 220310_at | 0.3683 | 0.4918 | |
| GSE77861 | TUBAL3 | 79861 | 220310_at | 0.0770 | 0.5797 | |
| GSE97050 | TUBAL3 | 79861 | A_33_P3332252 | -0.0704 | 0.7530 | |
| TCGA | TUBAL3 | 79861 | RNAseq | 1.2221 | 0.0028 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TUBAL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUBAL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBAL3 | 79861 | 6 | 7 | 17 | |
| GSE20123 | TUBAL3 | 79861 | 6 | 6 | 18 | |
| GSE43470 | TUBAL3 | 79861 | 4 | 6 | 33 | |
| GSE46452 | TUBAL3 | 79861 | 2 | 14 | 43 | |
| GSE47630 | TUBAL3 | 79861 | 6 | 14 | 20 | |
| GSE54993 | TUBAL3 | 79861 | 11 | 0 | 59 | |
| GSE54994 | TUBAL3 | 79861 | 5 | 10 | 38 | |
| GSE60625 | TUBAL3 | 79861 | 0 | 0 | 11 | |
| GSE74703 | TUBAL3 | 79861 | 3 | 4 | 29 | |
| GSE74704 | TUBAL3 | 79861 | 1 | 5 | 14 | |
| TCGA | TUBAL3 | 79861 | 20 | 24 | 52 |
Total number of gains: 64; Total number of losses: 90; Total Number of normals: 334.
Somatic mutations of TUBAL3:
Generating mutation plots.
Highly correlated genes for TUBAL3:
Showing top 20/157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBAL3 | NPW | 0.798314 | 3 | 0 | 3 |
| TUBAL3 | NPBWR1 | 0.757449 | 3 | 0 | 3 |
| TUBAL3 | ZFPM1 | 0.754916 | 3 | 0 | 3 |
| TUBAL3 | CHGB | 0.734283 | 3 | 0 | 3 |
| TUBAL3 | TMEM182 | 0.733847 | 3 | 0 | 3 |
| TUBAL3 | DYNC1LI1 | 0.719715 | 4 | 0 | 4 |
| TUBAL3 | SURF2 | 0.712928 | 3 | 0 | 3 |
| TUBAL3 | MTFP1 | 0.712272 | 3 | 0 | 3 |
| TUBAL3 | HOXC9 | 0.706917 | 3 | 0 | 3 |
| TUBAL3 | CLPB | 0.703314 | 4 | 0 | 4 |
| TUBAL3 | POLE4 | 0.702541 | 4 | 0 | 4 |
| TUBAL3 | KIF26B | 0.698791 | 4 | 0 | 4 |
| TUBAL3 | GINS2 | 0.696209 | 3 | 0 | 3 |
| TUBAL3 | NAV3 | 0.694235 | 4 | 0 | 3 |
| TUBAL3 | NUP62CL | 0.692233 | 3 | 0 | 3 |
| TUBAL3 | CDC6 | 0.690031 | 4 | 0 | 3 |
| TUBAL3 | DCBLD2 | 0.688375 | 3 | 0 | 3 |
| TUBAL3 | IGFL2 | 0.68077 | 4 | 0 | 3 |
| TUBAL3 | RIMS4 | 0.673217 | 4 | 0 | 4 |
| TUBAL3 | GALNS | 0.666534 | 4 | 0 | 3 |
For details and further investigation, click here
