| Full name: galactosamine (N-acetyl)-6-sulfatase | Alias Symbol: GAS|GALNAC6S | ||
| Type: protein-coding gene | Cytoband: 16q24.3 | ||
| Entrez ID: 2588 | HGNC ID: HGNC:4122 | Ensembl Gene: ENSG00000141012 | OMIM ID: 612222 |
| Drug and gene relationship at DGIdb | |||
Expression of GALNS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALNS | 2588 | 206335_at | 0.9047 | 0.2068 | |
| GSE20347 | GALNS | 2588 | 206335_at | 0.8320 | 0.0000 | |
| GSE23400 | GALNS | 2588 | 206335_at | 0.6144 | 0.0000 | |
| GSE26886 | GALNS | 2588 | 206335_at | 1.0469 | 0.0000 | |
| GSE29001 | GALNS | 2588 | 206335_at | 0.5087 | 0.0186 | |
| GSE38129 | GALNS | 2588 | 206335_at | 1.0696 | 0.0000 | |
| GSE45670 | GALNS | 2588 | 206335_at | 0.8270 | 0.0001 | |
| GSE53622 | GALNS | 2588 | 64543 | 1.0075 | 0.0000 | |
| GSE53624 | GALNS | 2588 | 64543 | 0.9275 | 0.0000 | |
| GSE63941 | GALNS | 2588 | 206335_at | -1.4317 | 0.0239 | |
| GSE77861 | GALNS | 2588 | 206335_at | 0.9090 | 0.0027 | |
| GSE97050 | GALNS | 2588 | A_23_P106562 | 0.8536 | 0.1241 | |
| SRP007169 | GALNS | 2588 | RNAseq | 1.4198 | 0.0008 | |
| SRP008496 | GALNS | 2588 | RNAseq | 1.2192 | 0.0002 | |
| SRP064894 | GALNS | 2588 | RNAseq | 1.1712 | 0.0000 | |
| SRP133303 | GALNS | 2588 | RNAseq | 1.5646 | 0.0000 | |
| SRP159526 | GALNS | 2588 | RNAseq | 1.6409 | 0.0021 | |
| SRP193095 | GALNS | 2588 | RNAseq | 1.0448 | 0.0000 | |
| SRP219564 | GALNS | 2588 | RNAseq | 0.7251 | 0.0416 | |
| TCGA | GALNS | 2588 | RNAseq | 0.2651 | 0.0006 |
Upregulated datasets: 9; Downregulated datasets: 1.
Survival by GALNS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALNS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALNS | 2588 | 4 | 3 | 23 | |
| GSE20123 | GALNS | 2588 | 4 | 3 | 23 | |
| GSE43470 | GALNS | 2588 | 1 | 13 | 29 | |
| GSE46452 | GALNS | 2588 | 38 | 1 | 20 | |
| GSE47630 | GALNS | 2588 | 11 | 9 | 20 | |
| GSE54993 | GALNS | 2588 | 3 | 4 | 63 | |
| GSE54994 | GALNS | 2588 | 9 | 11 | 33 | |
| GSE60625 | GALNS | 2588 | 4 | 0 | 7 | |
| GSE74703 | GALNS | 2588 | 1 | 9 | 26 | |
| GSE74704 | GALNS | 2588 | 3 | 2 | 15 | |
| TCGA | GALNS | 2588 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of GALNS:
Generating mutation plots.
Highly correlated genes for GALNS:
Showing top 20/689 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALNS | FMNL2 | 0.749974 | 6 | 0 | 6 |
| GALNS | C16orf74 | 0.741116 | 6 | 0 | 6 |
| GALNS | FBRSL1 | 0.740144 | 4 | 0 | 4 |
| GALNS | DOHH | 0.73842 | 3 | 0 | 3 |
| GALNS | IGF2BP2 | 0.732447 | 10 | 0 | 10 |
| GALNS | LRRC8E | 0.732023 | 5 | 0 | 5 |
| GALNS | RFX8 | 0.730016 | 3 | 0 | 3 |
| GALNS | BOP1 | 0.729812 | 3 | 0 | 3 |
| GALNS | SNAI2 | 0.729641 | 9 | 0 | 9 |
| GALNS | FSCN1 | 0.72221 | 11 | 0 | 10 |
| GALNS | COL10A1 | 0.714234 | 10 | 0 | 10 |
| GALNS | MRGBP | 0.712191 | 10 | 0 | 10 |
| GALNS | MMP11 | 0.710669 | 10 | 0 | 9 |
| GALNS | MYO10 | 0.707788 | 10 | 0 | 9 |
| GALNS | GPRIN1 | 0.705994 | 6 | 0 | 5 |
| GALNS | LRWD1 | 0.705183 | 3 | 0 | 3 |
| GALNS | CMC2 | 0.705101 | 9 | 0 | 9 |
| GALNS | USB1 | 0.704049 | 11 | 0 | 11 |
| GALNS | AGRN | 0.703276 | 10 | 0 | 10 |
| GALNS | PLAU | 0.703183 | 10 | 0 | 10 |
For details and further investigation, click here
