| Full name: dynein cytoplasmic 1 light intermediate chain 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p22.3 | ||
| Entrez ID: 51143 | HGNC ID: HGNC:18745 | Ensembl Gene: ENSG00000144635 | OMIM ID: 615890 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DYNC1LI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYNC1LI1 | 51143 | 222479_s_at | 0.0980 | 0.7429 | |
| GSE20347 | DYNC1LI1 | 51143 | 217976_s_at | 0.0606 | 0.8146 | |
| GSE23400 | DYNC1LI1 | 51143 | 217976_s_at | 0.3331 | 0.0000 | |
| GSE26886 | DYNC1LI1 | 51143 | 222479_s_at | 0.1251 | 0.3842 | |
| GSE29001 | DYNC1LI1 | 51143 | 217976_s_at | 0.4356 | 0.3188 | |
| GSE38129 | DYNC1LI1 | 51143 | 217976_s_at | 0.0057 | 0.9779 | |
| GSE45670 | DYNC1LI1 | 51143 | 222479_s_at | -0.0790 | 0.6087 | |
| GSE63941 | DYNC1LI1 | 51143 | 222479_s_at | 0.0566 | 0.9044 | |
| GSE77861 | DYNC1LI1 | 51143 | 222479_s_at | 0.0321 | 0.8893 | |
| GSE97050 | DYNC1LI1 | 51143 | A_23_P69141 | 0.1556 | 0.5391 | |
| SRP007169 | DYNC1LI1 | 51143 | RNAseq | -0.2232 | 0.5247 | |
| SRP008496 | DYNC1LI1 | 51143 | RNAseq | 0.0238 | 0.9123 | |
| SRP064894 | DYNC1LI1 | 51143 | RNAseq | 0.3298 | 0.0049 | |
| SRP133303 | DYNC1LI1 | 51143 | RNAseq | 0.2256 | 0.1383 | |
| SRP159526 | DYNC1LI1 | 51143 | RNAseq | 0.1684 | 0.6220 | |
| SRP193095 | DYNC1LI1 | 51143 | RNAseq | -0.0684 | 0.4975 | |
| SRP219564 | DYNC1LI1 | 51143 | RNAseq | -0.3121 | 0.1805 | |
| TCGA | DYNC1LI1 | 51143 | RNAseq | 0.0362 | 0.4978 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DYNC1LI1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of DYNC1LI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYNC1LI1 | 51143 | 0 | 18 | 12 | |
| GSE20123 | DYNC1LI1 | 51143 | 0 | 18 | 12 | |
| GSE43470 | DYNC1LI1 | 51143 | 1 | 20 | 22 | |
| GSE46452 | DYNC1LI1 | 51143 | 2 | 17 | 40 | |
| GSE47630 | DYNC1LI1 | 51143 | 1 | 25 | 14 | |
| GSE54993 | DYNC1LI1 | 51143 | 6 | 3 | 61 | |
| GSE54994 | DYNC1LI1 | 51143 | 1 | 32 | 20 | |
| GSE60625 | DYNC1LI1 | 51143 | 5 | 0 | 6 | |
| GSE74703 | DYNC1LI1 | 51143 | 1 | 17 | 18 | |
| GSE74704 | DYNC1LI1 | 51143 | 0 | 12 | 8 | |
| TCGA | DYNC1LI1 | 51143 | 2 | 69 | 25 |
Total number of gains: 19; Total number of losses: 231; Total Number of normals: 238.
Somatic mutations of DYNC1LI1:
Generating mutation plots.
Highly correlated genes for DYNC1LI1:
Showing top 20/32 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYNC1LI1 | TUBAL3 | 0.719715 | 4 | 0 | 4 |
| DYNC1LI1 | HEATR4 | 0.644524 | 4 | 0 | 4 |
| DYNC1LI1 | YEATS4 | 0.636059 | 4 | 0 | 3 |
| DYNC1LI1 | ABCG8 | 0.630091 | 3 | 0 | 3 |
| DYNC1LI1 | EFCAB11 | 0.625971 | 4 | 0 | 3 |
| DYNC1LI1 | EDEM3 | 0.590491 | 4 | 0 | 3 |
| DYNC1LI1 | SNAI2 | 0.580829 | 4 | 0 | 3 |
| DYNC1LI1 | FFAR1 | 0.580795 | 4 | 0 | 3 |
| DYNC1LI1 | RAB29 | 0.580142 | 4 | 0 | 3 |
| DYNC1LI1 | OSBPL11 | 0.579627 | 5 | 0 | 3 |
| DYNC1LI1 | PINX1 | 0.577269 | 4 | 0 | 3 |
| DYNC1LI1 | DCBLD2 | 0.575076 | 4 | 0 | 3 |
| DYNC1LI1 | METTL4 | 0.573012 | 4 | 0 | 3 |
| DYNC1LI1 | L3HYPDH | 0.563669 | 3 | 0 | 3 |
| DYNC1LI1 | POLR3G | 0.560121 | 6 | 0 | 4 |
| DYNC1LI1 | NID2 | 0.556716 | 7 | 0 | 3 |
| DYNC1LI1 | ZPR1 | 0.545321 | 4 | 0 | 3 |
| DYNC1LI1 | GALK2 | 0.542991 | 5 | 0 | 3 |
| DYNC1LI1 | CNIH1 | 0.536663 | 5 | 0 | 3 |
| DYNC1LI1 | TCFL5 | 0.534721 | 6 | 0 | 3 |
For details and further investigation, click here
