| Full name: pre-mRNA processing factor 19 | Alias Symbol: UBOX4|NMP200|PSO4|hPSO4|SNEV | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 27339 | HGNC ID: HGNC:17896 | Ensembl Gene: ENSG00000110107 | OMIM ID: 608330 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPF19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPF19 | 27339 | 203103_s_at | 0.4044 | 0.1670 | |
| GSE20347 | PRPF19 | 27339 | 203103_s_at | 0.3692 | 0.0022 | |
| GSE23400 | PRPF19 | 27339 | 203103_s_at | 0.4735 | 0.0000 | |
| GSE26886 | PRPF19 | 27339 | 203103_s_at | 1.1163 | 0.0010 | |
| GSE29001 | PRPF19 | 27339 | 203103_s_at | 0.0742 | 0.8619 | |
| GSE38129 | PRPF19 | 27339 | 203103_s_at | 0.5559 | 0.0000 | |
| GSE45670 | PRPF19 | 27339 | 203103_s_at | 0.3163 | 0.0432 | |
| GSE53622 | PRPF19 | 27339 | 31591 | 0.0701 | 0.0848 | |
| GSE53624 | PRPF19 | 27339 | 31591 | 0.2783 | 0.0000 | |
| GSE63941 | PRPF19 | 27339 | 203103_s_at | 1.2161 | 0.0033 | |
| GSE77861 | PRPF19 | 27339 | 203103_s_at | 0.5442 | 0.0127 | |
| GSE97050 | PRPF19 | 27339 | A_33_P3363012 | 0.0752 | 0.7171 | |
| SRP007169 | PRPF19 | 27339 | RNAseq | 0.5815 | 0.1772 | |
| SRP008496 | PRPF19 | 27339 | RNAseq | 0.3009 | 0.2640 | |
| SRP064894 | PRPF19 | 27339 | RNAseq | 0.2627 | 0.1440 | |
| SRP133303 | PRPF19 | 27339 | RNAseq | 0.1882 | 0.3315 | |
| SRP159526 | PRPF19 | 27339 | RNAseq | 0.4790 | 0.0253 | |
| SRP193095 | PRPF19 | 27339 | RNAseq | 0.3332 | 0.0028 | |
| SRP219564 | PRPF19 | 27339 | RNAseq | 0.5975 | 0.0812 | |
| TCGA | PRPF19 | 27339 | RNAseq | 0.2569 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PRPF19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPF19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPF19 | 27339 | 2 | 5 | 23 | |
| GSE20123 | PRPF19 | 27339 | 2 | 5 | 23 | |
| GSE43470 | PRPF19 | 27339 | 2 | 6 | 35 | |
| GSE46452 | PRPF19 | 27339 | 8 | 4 | 47 | |
| GSE47630 | PRPF19 | 27339 | 3 | 8 | 29 | |
| GSE54993 | PRPF19 | 27339 | 3 | 0 | 67 | |
| GSE54994 | PRPF19 | 27339 | 5 | 5 | 43 | |
| GSE60625 | PRPF19 | 27339 | 0 | 3 | 8 | |
| GSE74703 | PRPF19 | 27339 | 2 | 3 | 31 | |
| GSE74704 | PRPF19 | 27339 | 2 | 3 | 15 | |
| TCGA | PRPF19 | 27339 | 15 | 10 | 71 |
Total number of gains: 44; Total number of losses: 52; Total Number of normals: 392.
Somatic mutations of PRPF19:
Generating mutation plots.
Highly correlated genes for PRPF19:
Showing top 20/463 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPF19 | ABCC6 | 0.74792 | 3 | 0 | 3 |
| PRPF19 | SDCCAG8 | 0.73536 | 4 | 0 | 4 |
| PRPF19 | FEN1 | 0.699564 | 10 | 0 | 10 |
| PRPF19 | SNORA71A | 0.693965 | 3 | 0 | 3 |
| PRPF19 | MAP7D2 | 0.693768 | 3 | 0 | 3 |
| PRPF19 | UBE2I | 0.692946 | 7 | 0 | 7 |
| PRPF19 | UFSP1 | 0.691531 | 4 | 0 | 3 |
| PRPF19 | IRAK1 | 0.68568 | 8 | 0 | 7 |
| PRPF19 | SOGA1 | 0.683898 | 3 | 0 | 3 |
| PRPF19 | INTS5 | 0.674946 | 10 | 0 | 9 |
| PRPF19 | POLR3A | 0.670905 | 4 | 0 | 3 |
| PRPF19 | SAC3D1 | 0.670476 | 11 | 0 | 9 |
| PRPF19 | ZDHHC8 | 0.666045 | 4 | 0 | 3 |
| PRPF19 | RBM28 | 0.665751 | 8 | 0 | 8 |
| PRPF19 | MDC1 | 0.66515 | 6 | 0 | 4 |
| PRPF19 | PUS1 | 0.664574 | 11 | 0 | 10 |
| PRPF19 | MIIP | 0.663965 | 5 | 0 | 4 |
| PRPF19 | COA6 | 0.66302 | 5 | 0 | 4 |
| PRPF19 | WDR90 | 0.66163 | 5 | 0 | 4 |
| PRPF19 | YDJC | 0.66019 | 6 | 0 | 5 |
For details and further investigation, click here
