| Full name: upper zone of growth plate and cartilage matrix associated | Alias Symbol: GRP | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 221044 | HGNC ID: HGNC:25205 | Ensembl Gene: ENSG00000165623 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of UCMA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UCMA | 221044 | 236800_at | 0.0206 | 0.9609 | |
| GSE26886 | UCMA | 221044 | 236800_at | -0.1686 | 0.1821 | |
| GSE45670 | UCMA | 221044 | 236800_at | 0.0334 | 0.8048 | |
| GSE53622 | UCMA | 221044 | 56218 | -0.5742 | 0.0001 | |
| GSE53624 | UCMA | 221044 | 56218 | -1.0602 | 0.0000 | |
| GSE63941 | UCMA | 221044 | 236800_at | -0.0564 | 0.7513 | |
| GSE77861 | UCMA | 221044 | 236800_at | -0.1102 | 0.2945 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UCMA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UCMA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UCMA | 221044 | 5 | 7 | 18 | |
| GSE20123 | UCMA | 221044 | 5 | 6 | 19 | |
| GSE43470 | UCMA | 221044 | 3 | 5 | 35 | |
| GSE46452 | UCMA | 221044 | 2 | 14 | 43 | |
| GSE47630 | UCMA | 221044 | 6 | 14 | 20 | |
| GSE54993 | UCMA | 221044 | 11 | 1 | 58 | |
| GSE54994 | UCMA | 221044 | 4 | 9 | 40 | |
| GSE60625 | UCMA | 221044 | 0 | 0 | 11 | |
| GSE74703 | UCMA | 221044 | 2 | 3 | 31 | |
| GSE74704 | UCMA | 221044 | 1 | 5 | 14 | |
| TCGA | UCMA | 221044 | 21 | 24 | 51 |
Total number of gains: 60; Total number of losses: 88; Total Number of normals: 340.
Somatic mutations of UCMA:
Generating mutation plots.
Highly correlated genes for UCMA:
Showing top 20/74 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UCMA | HHATL | 0.765851 | 3 | 0 | 3 |
| UCMA | SLC22A14 | 0.694516 | 5 | 0 | 5 |
| UCMA | ANK1 | 0.682946 | 3 | 0 | 3 |
| UCMA | CD300LG | 0.674819 | 3 | 0 | 3 |
| UCMA | PSG5 | 0.657464 | 3 | 0 | 3 |
| UCMA | HYAL4 | 0.635424 | 3 | 0 | 3 |
| UCMA | LINC00955 | 0.633875 | 3 | 0 | 3 |
| UCMA | EPHA8 | 0.619835 | 4 | 0 | 4 |
| UCMA | TREML1 | 0.616292 | 3 | 0 | 3 |
| UCMA | CAV3 | 0.610461 | 3 | 0 | 3 |
| UCMA | CYB5RL | 0.605681 | 3 | 0 | 3 |
| UCMA | CALML6 | 0.604137 | 4 | 0 | 3 |
| UCMA | CSMD2-AS1 | 0.601122 | 3 | 0 | 3 |
| UCMA | TNFRSF10C | 0.599597 | 3 | 0 | 3 |
| UCMA | OR2H1 | 0.598545 | 3 | 0 | 3 |
| UCMA | PAPPA2 | 0.596349 | 4 | 0 | 4 |
| UCMA | TMEM95 | 0.595215 | 3 | 0 | 3 |
| UCMA | HTR5A | 0.59241 | 3 | 0 | 3 |
| UCMA | DAO | 0.583841 | 5 | 0 | 3 |
| UCMA | HPX | 0.583594 | 4 | 0 | 3 |
For details and further investigation, click here
