| Full name: pregnancy specific beta-1-glycoprotein 5 | Alias Symbol: FL-NCA-3|PSG | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 5673 | HGNC ID: HGNC:9522 | Ensembl Gene: ENSG00000204941 | OMIM ID: 176394 |
| Drug and gene relationship at DGIdb | |||
Expression of PSG5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSG5 | 5673 | 239583_x_at | -0.0812 | 0.8146 | |
| GSE20347 | PSG5 | 5673 | 204830_x_at | 0.0284 | 0.7270 | |
| GSE23400 | PSG5 | 5673 | 204830_x_at | -0.1069 | 0.0044 | |
| GSE26886 | PSG5 | 5673 | 239583_x_at | -0.1933 | 0.1395 | |
| GSE29001 | PSG5 | 5673 | 204830_x_at | -0.2232 | 0.2049 | |
| GSE38129 | PSG5 | 5673 | 204830_x_at | 0.0971 | 0.4986 | |
| GSE45670 | PSG5 | 5673 | 239583_x_at | 0.0468 | 0.6762 | |
| GSE53622 | PSG5 | 5673 | 91036 | 0.4729 | 0.0000 | |
| GSE53624 | PSG5 | 5673 | 91036 | 0.7110 | 0.0000 | |
| GSE63941 | PSG5 | 5673 | 239583_x_at | 0.0772 | 0.7212 | |
| GSE77861 | PSG5 | 5673 | 239583_x_at | -0.1349 | 0.1579 | |
| GSE97050 | PSG5 | 5673 | A_33_P3372217 | -0.6084 | 0.2396 | |
| TCGA | PSG5 | 5673 | RNAseq | 4.7384 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PSG5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSG5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSG5 | 5673 | 6 | 5 | 19 | |
| GSE20123 | PSG5 | 5673 | 5 | 4 | 21 | |
| GSE43470 | PSG5 | 5673 | 4 | 11 | 28 | |
| GSE46452 | PSG5 | 5673 | 45 | 1 | 13 | |
| GSE47630 | PSG5 | 5673 | 8 | 6 | 26 | |
| GSE54993 | PSG5 | 5673 | 17 | 4 | 49 | |
| GSE54994 | PSG5 | 5673 | 7 | 12 | 34 | |
| GSE60625 | PSG5 | 5673 | 9 | 0 | 2 | |
| GSE74703 | PSG5 | 5673 | 4 | 7 | 25 | |
| GSE74704 | PSG5 | 5673 | 4 | 2 | 14 | |
| TCGA | PSG5 | 5673 | 14 | 15 | 67 |
Total number of gains: 123; Total number of losses: 67; Total Number of normals: 298.
Somatic mutations of PSG5:
Generating mutation plots.
Highly correlated genes for PSG5:
Showing top 20/483 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSG5 | GJB4 | 0.761882 | 4 | 0 | 4 |
| PSG5 | UBE2F | 0.734857 | 3 | 0 | 3 |
| PSG5 | HHLA1 | 0.729044 | 6 | 0 | 6 |
| PSG5 | TBC1D21 | 0.723348 | 3 | 0 | 3 |
| PSG5 | LRRC28 | 0.717315 | 3 | 0 | 3 |
| PSG5 | SPRR1A | 0.702457 | 3 | 0 | 3 |
| PSG5 | ABCG4 | 0.700016 | 5 | 0 | 4 |
| PSG5 | WNT10B | 0.698053 | 3 | 0 | 3 |
| PSG5 | RFFL | 0.69516 | 3 | 0 | 3 |
| PSG5 | PPP1R11 | 0.693178 | 3 | 0 | 3 |
| PSG5 | TSSK2 | 0.691076 | 4 | 0 | 3 |
| PSG5 | ADAM11 | 0.689226 | 6 | 0 | 6 |
| PSG5 | RBPJL | 0.687444 | 5 | 0 | 5 |
| PSG5 | SPAG6 | 0.680635 | 3 | 0 | 3 |
| PSG5 | TREML2 | 0.673349 | 5 | 0 | 5 |
| PSG5 | NNAT | 0.670661 | 4 | 0 | 4 |
| PSG5 | CCKAR | 0.670532 | 3 | 0 | 3 |
| PSG5 | C11orf16 | 0.669263 | 5 | 0 | 5 |
| PSG5 | NAGA | 0.666603 | 3 | 0 | 3 |
| PSG5 | CASR | 0.665891 | 4 | 0 | 4 |
For details and further investigation, click here
