| Full name: calcium voltage-gated channel auxiliary subunit gamma 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q24.2 | ||
| Entrez ID: 786 | HGNC ID: HGNC:1405 | Ensembl Gene: ENSG00000108878 | OMIM ID: 114209 |
| Drug and gene relationship at DGIdb | |||
CACNG1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04261 | Adrenergic signaling in cardiomyocytes | |
| hsa04921 | Oxytocin signaling pathway |
Expression of CACNG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACNG1 | 786 | 206612_at | 0.0383 | 0.8472 | |
| GSE20347 | CACNG1 | 786 | 206612_at | 0.0421 | 0.7136 | |
| GSE23400 | CACNG1 | 786 | 206612_at | -0.0314 | 0.3545 | |
| GSE26886 | CACNG1 | 786 | 206612_at | -0.0155 | 0.9148 | |
| GSE29001 | CACNG1 | 786 | 206612_at | -0.0766 | 0.6737 | |
| GSE38129 | CACNG1 | 786 | 206612_at | 0.0003 | 0.9974 | |
| GSE45670 | CACNG1 | 786 | 206612_at | 0.0938 | 0.3110 | |
| GSE53622 | CACNG1 | 786 | 22380 | 0.4933 | 0.0000 | |
| GSE53624 | CACNG1 | 786 | 22380 | 0.7657 | 0.0000 | |
| GSE63941 | CACNG1 | 786 | 206612_at | 0.0489 | 0.8068 | |
| GSE77861 | CACNG1 | 786 | 206612_at | 0.0227 | 0.8787 | |
| TCGA | CACNG1 | 786 | RNAseq | -0.6841 | 0.4334 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CACNG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CACNG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACNG1 | 786 | 3 | 2 | 25 | |
| GSE20123 | CACNG1 | 786 | 3 | 2 | 25 | |
| GSE43470 | CACNG1 | 786 | 5 | 0 | 38 | |
| GSE46452 | CACNG1 | 786 | 31 | 1 | 27 | |
| GSE47630 | CACNG1 | 786 | 7 | 1 | 32 | |
| GSE54993 | CACNG1 | 786 | 2 | 5 | 63 | |
| GSE54994 | CACNG1 | 786 | 9 | 4 | 40 | |
| GSE60625 | CACNG1 | 786 | 4 | 2 | 5 | |
| GSE74703 | CACNG1 | 786 | 5 | 0 | 31 | |
| GSE74704 | CACNG1 | 786 | 3 | 1 | 16 | |
| TCGA | CACNG1 | 786 | 28 | 9 | 59 |
Total number of gains: 100; Total number of losses: 27; Total Number of normals: 361.
Somatic mutations of CACNG1:
Generating mutation plots.
Highly correlated genes for CACNG1:
Showing top 20/543 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACNG1 | TCL6 | 0.712809 | 3 | 0 | 3 |
| CACNG1 | IFNA10 | 0.707506 | 4 | 0 | 4 |
| CACNG1 | JAK3 | 0.694443 | 4 | 0 | 4 |
| CACNG1 | DAB1 | 0.694002 | 5 | 0 | 5 |
| CACNG1 | GPA33 | 0.693178 | 4 | 0 | 4 |
| CACNG1 | PHLDB1 | 0.689886 | 4 | 0 | 4 |
| CACNG1 | KRTAP5-8 | 0.688908 | 5 | 0 | 5 |
| CACNG1 | IFT122 | 0.688461 | 3 | 0 | 3 |
| CACNG1 | OR10H3 | 0.686295 | 4 | 0 | 4 |
| CACNG1 | MEPE | 0.684041 | 5 | 0 | 5 |
| CACNG1 | CDH4 | 0.677309 | 3 | 0 | 3 |
| CACNG1 | OR7E24 | 0.67588 | 4 | 0 | 4 |
| CACNG1 | CYP4A11 | 0.672717 | 4 | 0 | 4 |
| CACNG1 | CIITA | 0.67162 | 5 | 0 | 4 |
| CACNG1 | SCGN | 0.66955 | 4 | 0 | 3 |
| CACNG1 | FOLH1 | 0.668666 | 4 | 0 | 4 |
| CACNG1 | CCDC87 | 0.667869 | 5 | 0 | 5 |
| CACNG1 | UGT2B28 | 0.66644 | 4 | 0 | 4 |
| CACNG1 | PDE3B | 0.666371 | 5 | 0 | 4 |
| CACNG1 | ART1 | 0.665088 | 4 | 0 | 4 |
For details and further investigation, click here
