| Full name: TATA-box binding protein associated factor 6 like | Alias Symbol: PAF65A | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 10629 | HGNC ID: HGNC:17305 | Ensembl Gene: ENSG00000162227 | OMIM ID: 602946 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF6L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF6L | 10629 | 230049_at | 0.0005 | 0.9988 | |
| GSE20347 | TAF6L | 10629 | 213209_at | 0.1297 | 0.1378 | |
| GSE23400 | TAF6L | 10629 | 213209_at | 0.0999 | 0.0143 | |
| GSE26886 | TAF6L | 10629 | 213210_at | 0.1032 | 0.5426 | |
| GSE29001 | TAF6L | 10629 | 213209_at | -0.0967 | 0.5881 | |
| GSE38129 | TAF6L | 10629 | 213210_at | -0.1193 | 0.1454 | |
| GSE45670 | TAF6L | 10629 | 230049_at | 0.0197 | 0.8314 | |
| GSE53622 | TAF6L | 10629 | 34579 | 0.4098 | 0.0000 | |
| GSE53624 | TAF6L | 10629 | 34579 | 0.4786 | 0.0000 | |
| GSE63941 | TAF6L | 10629 | 213210_at | 0.6870 | 0.0273 | |
| GSE77861 | TAF6L | 10629 | 230049_at | -0.1035 | 0.4208 | |
| GSE97050 | TAF6L | 10629 | A_33_P3266080 | 0.2860 | 0.2330 | |
| SRP007169 | TAF6L | 10629 | RNAseq | 0.0654 | 0.8761 | |
| SRP008496 | TAF6L | 10629 | RNAseq | 0.0690 | 0.8232 | |
| SRP064894 | TAF6L | 10629 | RNAseq | 0.3824 | 0.0241 | |
| SRP133303 | TAF6L | 10629 | RNAseq | -0.0405 | 0.8165 | |
| SRP159526 | TAF6L | 10629 | RNAseq | 0.5673 | 0.0890 | |
| SRP193095 | TAF6L | 10629 | RNAseq | 0.2334 | 0.0066 | |
| SRP219564 | TAF6L | 10629 | RNAseq | 0.3226 | 0.2656 | |
| TCGA | TAF6L | 10629 | RNAseq | 0.2517 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF6L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF6L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF6L | 10629 | 6 | 5 | 19 | |
| GSE20123 | TAF6L | 10629 | 6 | 5 | 19 | |
| GSE43470 | TAF6L | 10629 | 1 | 6 | 36 | |
| GSE46452 | TAF6L | 10629 | 8 | 4 | 47 | |
| GSE47630 | TAF6L | 10629 | 3 | 7 | 30 | |
| GSE54993 | TAF6L | 10629 | 3 | 0 | 67 | |
| GSE54994 | TAF6L | 10629 | 5 | 5 | 43 | |
| GSE60625 | TAF6L | 10629 | 0 | 3 | 8 | |
| GSE74703 | TAF6L | 10629 | 1 | 3 | 32 | |
| GSE74704 | TAF6L | 10629 | 4 | 3 | 13 | |
| TCGA | TAF6L | 10629 | 12 | 11 | 73 |
Total number of gains: 49; Total number of losses: 52; Total Number of normals: 387.
Somatic mutations of TAF6L:
Generating mutation plots.
Highly correlated genes for TAF6L:
Showing top 20/354 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF6L | CLC | 0.789731 | 3 | 0 | 3 |
| TAF6L | PRLR | 0.751016 | 3 | 0 | 3 |
| TAF6L | JAK3 | 0.720291 | 4 | 0 | 3 |
| TAF6L | MAPK8IP3 | 0.714413 | 3 | 0 | 3 |
| TAF6L | GDF5 | 0.713961 | 3 | 0 | 3 |
| TAF6L | CXCR5 | 0.70204 | 3 | 0 | 3 |
| TAF6L | PLXNB3 | 0.69127 | 3 | 0 | 3 |
| TAF6L | GGN | 0.688367 | 3 | 0 | 3 |
| TAF6L | CHST4 | 0.677242 | 3 | 0 | 3 |
| TAF6L | PRORY | 0.673737 | 3 | 0 | 3 |
| TAF6L | DNAH11 | 0.671006 | 3 | 0 | 3 |
| TAF6L | PLCB2 | 0.668271 | 4 | 0 | 3 |
| TAF6L | NES | 0.667825 | 3 | 0 | 3 |
| TAF6L | PIM2 | 0.667648 | 3 | 0 | 3 |
| TAF6L | KIR2DL4 | 0.667456 | 4 | 0 | 3 |
| TAF6L | UGT2B28 | 0.665628 | 4 | 0 | 4 |
| TAF6L | ZNF628 | 0.662101 | 3 | 0 | 3 |
| TAF6L | KCNK2 | 0.660626 | 4 | 0 | 3 |
| TAF6L | PIK3R5 | 0.660178 | 4 | 0 | 3 |
| TAF6L | TNFSF8 | 0.658477 | 5 | 0 | 4 |
For details and further investigation, click here
