| Full name: unc-51 like kinase 4 | Alias Symbol: FLJ20574|REC01035|FAM7C1 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 54986 | HGNC ID: HGNC:15784 | Ensembl Gene: ENSG00000168038 | OMIM ID: 617010 |
| Drug and gene relationship at DGIdb | |||
Expression of ULK4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ULK4 | 54986 | 232206_at | -0.2801 | 0.5030 | |
| GSE20347 | ULK4 | 54986 | 220958_at | 0.0118 | 0.8669 | |
| GSE23400 | ULK4 | 54986 | 220958_at | -0.0785 | 0.0164 | |
| GSE26886 | ULK4 | 54986 | 232206_at | 0.0127 | 0.9433 | |
| GSE29001 | ULK4 | 54986 | 220958_at | -0.0359 | 0.8352 | |
| GSE38129 | ULK4 | 54986 | 220958_at | -0.0217 | 0.7737 | |
| GSE45670 | ULK4 | 54986 | 232206_at | 0.0720 | 0.5668 | |
| GSE53622 | ULK4 | 54986 | 31758 | 0.0019 | 0.9879 | |
| GSE53624 | ULK4 | 54986 | 31758 | -0.0654 | 0.4584 | |
| GSE63941 | ULK4 | 54986 | 244168_s_at | 0.3750 | 0.0545 | |
| GSE77861 | ULK4 | 54986 | 244168_s_at | 0.0925 | 0.5451 | |
| SRP007169 | ULK4 | 54986 | RNAseq | -0.3788 | 0.4947 | |
| SRP008496 | ULK4 | 54986 | RNAseq | -0.1020 | 0.7996 | |
| SRP064894 | ULK4 | 54986 | RNAseq | 0.2167 | 0.3303 | |
| SRP133303 | ULK4 | 54986 | RNAseq | -0.2910 | 0.2512 | |
| SRP159526 | ULK4 | 54986 | RNAseq | 0.0098 | 0.9804 | |
| SRP193095 | ULK4 | 54986 | RNAseq | -0.1002 | 0.4859 | |
| SRP219564 | ULK4 | 54986 | RNAseq | -0.0775 | 0.8804 | |
| TCGA | ULK4 | 54986 | RNAseq | -0.0347 | 0.7934 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ULK4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ULK4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ULK4 | 54986 | 0 | 19 | 11 | |
| GSE20123 | ULK4 | 54986 | 0 | 19 | 11 | |
| GSE43470 | ULK4 | 54986 | 0 | 21 | 22 | |
| GSE46452 | ULK4 | 54986 | 2 | 17 | 40 | |
| GSE47630 | ULK4 | 54986 | 2 | 25 | 13 | |
| GSE54993 | ULK4 | 54986 | 7 | 2 | 61 | |
| GSE54994 | ULK4 | 54986 | 2 | 33 | 18 | |
| GSE60625 | ULK4 | 54986 | 5 | 0 | 6 | |
| GSE74703 | ULK4 | 54986 | 0 | 17 | 19 | |
| GSE74704 | ULK4 | 54986 | 0 | 13 | 7 | |
| TCGA | ULK4 | 54986 | 1 | 71 | 24 |
Total number of gains: 19; Total number of losses: 237; Total Number of normals: 232.
Somatic mutations of ULK4:
Generating mutation plots.
Highly correlated genes for ULK4:
Showing top 20/510 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ULK4 | FRMPD4 | 0.743395 | 3 | 0 | 3 |
| ULK4 | CIITA | 0.710965 | 4 | 0 | 4 |
| ULK4 | RPS6KA6 | 0.710523 | 3 | 0 | 3 |
| ULK4 | LUZP4 | 0.701531 | 4 | 0 | 4 |
| ULK4 | EPOR | 0.699425 | 4 | 0 | 4 |
| ULK4 | IFNA5 | 0.69521 | 3 | 0 | 3 |
| ULK4 | SSUH2 | 0.69022 | 3 | 0 | 3 |
| ULK4 | NUDT7 | 0.680128 | 3 | 0 | 3 |
| ULK4 | HECW1 | 0.677595 | 4 | 0 | 4 |
| ULK4 | GK2 | 0.6771 | 3 | 0 | 3 |
| ULK4 | TCAP | 0.675473 | 3 | 0 | 3 |
| ULK4 | MSH4 | 0.670313 | 3 | 0 | 3 |
| ULK4 | NTNG1 | 0.669925 | 3 | 0 | 3 |
| ULK4 | CCDC87 | 0.669893 | 3 | 0 | 3 |
| ULK4 | GABRD | 0.66647 | 3 | 0 | 3 |
| ULK4 | CCR3 | 0.666383 | 3 | 0 | 3 |
| ULK4 | RIT2 | 0.663103 | 3 | 0 | 3 |
| ULK4 | MAPK4 | 0.662071 | 5 | 0 | 4 |
| ULK4 | SYT5 | 0.661536 | 4 | 0 | 4 |
| ULK4 | CRHR2 | 0.66116 | 4 | 0 | 4 |
For details and further investigation, click here
