| Full name: thioredoxin like 1 | Alias Symbol: Txl|TRP32 | ||
| Type: protein-coding gene | Cytoband: 18q21.31 | ||
| Entrez ID: 9352 | HGNC ID: HGNC:12436 | Ensembl Gene: ENSG00000091164 | OMIM ID: 603049 |
| Drug and gene relationship at DGIdb | |||
Expression of TXNL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNL1 | 9352 | 201588_at | -0.1267 | 0.8196 | |
| GSE20347 | TXNL1 | 9352 | 201588_at | -0.3676 | 0.0010 | |
| GSE23400 | TXNL1 | 9352 | 201588_at | -0.2855 | 0.0001 | |
| GSE26886 | TXNL1 | 9352 | 201588_at | -0.6374 | 0.0004 | |
| GSE29001 | TXNL1 | 9352 | 201588_at | -0.7769 | 0.0194 | |
| GSE38129 | TXNL1 | 9352 | 201588_at | -0.2397 | 0.0323 | |
| GSE45670 | TXNL1 | 9352 | 201588_at | -0.3133 | 0.0146 | |
| GSE53622 | TXNL1 | 9352 | 77346 | -0.8366 | 0.0000 | |
| GSE53624 | TXNL1 | 9352 | 77346 | -0.4640 | 0.0000 | |
| GSE63941 | TXNL1 | 9352 | 201588_at | -0.7452 | 0.1413 | |
| GSE77861 | TXNL1 | 9352 | 201588_at | -0.3980 | 0.3228 | |
| GSE97050 | TXNL1 | 9352 | A_23_P4522 | -0.4651 | 0.1502 | |
| SRP007169 | TXNL1 | 9352 | RNAseq | -1.6901 | 0.0000 | |
| SRP008496 | TXNL1 | 9352 | RNAseq | -1.4722 | 0.0000 | |
| SRP064894 | TXNL1 | 9352 | RNAseq | -0.7694 | 0.0000 | |
| SRP133303 | TXNL1 | 9352 | RNAseq | -0.5015 | 0.0047 | |
| SRP159526 | TXNL1 | 9352 | RNAseq | -0.4146 | 0.2744 | |
| SRP193095 | TXNL1 | 9352 | RNAseq | -0.6340 | 0.0000 | |
| SRP219564 | TXNL1 | 9352 | RNAseq | -0.8814 | 0.0032 | |
| TCGA | TXNL1 | 9352 | RNAseq | -0.0259 | 0.6048 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TXNL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TXNL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNL1 | 9352 | 2 | 9 | 19 | |
| GSE20123 | TXNL1 | 9352 | 2 | 9 | 19 | |
| GSE43470 | TXNL1 | 9352 | 0 | 5 | 38 | |
| GSE46452 | TXNL1 | 9352 | 1 | 26 | 32 | |
| GSE47630 | TXNL1 | 9352 | 5 | 20 | 15 | |
| GSE54993 | TXNL1 | 9352 | 10 | 0 | 60 | |
| GSE54994 | TXNL1 | 9352 | 1 | 18 | 34 | |
| GSE60625 | TXNL1 | 9352 | 0 | 4 | 7 | |
| GSE74703 | TXNL1 | 9352 | 0 | 5 | 31 | |
| GSE74704 | TXNL1 | 9352 | 2 | 6 | 12 | |
| TCGA | TXNL1 | 9352 | 8 | 44 | 44 |
Total number of gains: 31; Total number of losses: 146; Total Number of normals: 311.
Somatic mutations of TXNL1:
Generating mutation plots.
Highly correlated genes for TXNL1:
Showing top 20/1106 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNL1 | LYRM7 | 0.742161 | 3 | 0 | 3 |
| TXNL1 | GPCPD1 | 0.734077 | 3 | 0 | 3 |
| TXNL1 | HDHD2 | 0.724346 | 6 | 0 | 5 |
| TXNL1 | UNK | 0.722007 | 3 | 0 | 3 |
| TXNL1 | GGA3 | 0.717749 | 4 | 0 | 4 |
| TXNL1 | TAB3 | 0.711983 | 5 | 0 | 5 |
| TXNL1 | NOP10 | 0.710954 | 3 | 0 | 3 |
| TXNL1 | TUBB6 | 0.699316 | 4 | 0 | 4 |
| TXNL1 | STAM2 | 0.698285 | 3 | 0 | 3 |
| TXNL1 | MBD2 | 0.697988 | 13 | 0 | 11 |
| TXNL1 | HIPK1 | 0.694348 | 6 | 0 | 6 |
| TXNL1 | SLCO2A1 | 0.693339 | 3 | 0 | 3 |
| TXNL1 | ASCC3 | 0.688421 | 3 | 0 | 3 |
| TXNL1 | MIF4GD | 0.685865 | 3 | 0 | 3 |
| TXNL1 | USP24 | 0.683642 | 3 | 0 | 3 |
| TXNL1 | ZNF143 | 0.683563 | 4 | 0 | 4 |
| TXNL1 | VPS4B | 0.683244 | 13 | 0 | 12 |
| TXNL1 | CCDC12 | 0.675277 | 5 | 0 | 4 |
| TXNL1 | CCNG1 | 0.675024 | 7 | 0 | 7 |
| TXNL1 | PDE12 | 0.670161 | 7 | 0 | 6 |
For details and further investigation, click here
