| Full name: RUN and FYVE domain containing 1 | Alias Symbol: FLJ22251|ZFYVE12|RABIP4 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 80230 | HGNC ID: HGNC:19760 | Ensembl Gene: ENSG00000176783 | OMIM ID: 610327 |
| Drug and gene relationship at DGIdb | |||
Expression of RUFY1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RUFY1 | 80230 | 218243_at | -0.3910 | 0.3312 | |
| GSE20347 | RUFY1 | 80230 | 218243_at | -0.9706 | 0.0000 | |
| GSE23400 | RUFY1 | 80230 | 218243_at | -0.4196 | 0.0000 | |
| GSE26886 | RUFY1 | 80230 | 218243_at | -0.3529 | 0.1120 | |
| GSE29001 | RUFY1 | 80230 | 218243_at | -0.8735 | 0.0002 | |
| GSE38129 | RUFY1 | 80230 | 218243_at | -0.6966 | 0.0000 | |
| GSE45670 | RUFY1 | 80230 | 218243_at | -0.6516 | 0.0002 | |
| GSE53622 | RUFY1 | 80230 | 61043 | -0.7344 | 0.0000 | |
| GSE53624 | RUFY1 | 80230 | 61043 | -0.7782 | 0.0000 | |
| GSE63941 | RUFY1 | 80230 | 218243_at | 0.0174 | 0.9704 | |
| GSE77861 | RUFY1 | 80230 | 218243_at | -0.6811 | 0.0046 | |
| GSE97050 | RUFY1 | 80230 | A_23_P73457 | -0.3788 | 0.1782 | |
| SRP007169 | RUFY1 | 80230 | RNAseq | -1.3622 | 0.0015 | |
| SRP008496 | RUFY1 | 80230 | RNAseq | -1.3169 | 0.0000 | |
| SRP064894 | RUFY1 | 80230 | RNAseq | -0.6598 | 0.0000 | |
| SRP133303 | RUFY1 | 80230 | RNAseq | -0.3715 | 0.0638 | |
| SRP159526 | RUFY1 | 80230 | RNAseq | -0.6870 | 0.0164 | |
| SRP193095 | RUFY1 | 80230 | RNAseq | -0.5115 | 0.0000 | |
| SRP219564 | RUFY1 | 80230 | RNAseq | -0.3404 | 0.2960 | |
| TCGA | RUFY1 | 80230 | RNAseq | -0.0404 | 0.4449 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RUFY1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RUFY1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RUFY1 | 80230 | 2 | 12 | 16 | |
| GSE20123 | RUFY1 | 80230 | 2 | 12 | 16 | |
| GSE43470 | RUFY1 | 80230 | 1 | 11 | 31 | |
| GSE46452 | RUFY1 | 80230 | 0 | 27 | 32 | |
| GSE47630 | RUFY1 | 80230 | 1 | 20 | 19 | |
| GSE54993 | RUFY1 | 80230 | 10 | 2 | 58 | |
| GSE54994 | RUFY1 | 80230 | 2 | 17 | 34 | |
| GSE60625 | RUFY1 | 80230 | 1 | 0 | 10 | |
| GSE74703 | RUFY1 | 80230 | 1 | 7 | 28 | |
| GSE74704 | RUFY1 | 80230 | 1 | 6 | 13 | |
| TCGA | RUFY1 | 80230 | 10 | 34 | 52 |
Total number of gains: 31; Total number of losses: 148; Total Number of normals: 309.
Somatic mutations of RUFY1:
Generating mutation plots.
Highly correlated genes for RUFY1:
Showing top 20/1702 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RUFY1 | CCDC7 | 0.758477 | 3 | 0 | 3 |
| RUFY1 | UNK | 0.754689 | 3 | 0 | 3 |
| RUFY1 | SPRYD4 | 0.752729 | 4 | 0 | 3 |
| RUFY1 | UBL3 | 0.743895 | 10 | 0 | 10 |
| RUFY1 | ELMO2 | 0.742808 | 11 | 0 | 11 |
| RUFY1 | NDUFA7 | 0.741835 | 3 | 0 | 3 |
| RUFY1 | CA13 | 0.738245 | 3 | 0 | 3 |
| RUFY1 | ACOX3 | 0.732837 | 11 | 0 | 11 |
| RUFY1 | BLNK | 0.732559 | 12 | 0 | 11 |
| RUFY1 | CYP2J2 | 0.730462 | 10 | 0 | 9 |
| RUFY1 | RSPH3 | 0.730396 | 4 | 0 | 4 |
| RUFY1 | CDKN2C | 0.727914 | 3 | 0 | 3 |
| RUFY1 | RMND5B | 0.727729 | 12 | 0 | 10 |
| RUFY1 | ANO10 | 0.727405 | 10 | 0 | 10 |
| RUFY1 | STRADB | 0.727259 | 6 | 0 | 6 |
| RUFY1 | PDCD4 | 0.726015 | 3 | 0 | 3 |
| RUFY1 | KCTD6 | 0.72515 | 6 | 0 | 6 |
| RUFY1 | LRBA | 0.721891 | 11 | 0 | 11 |
| RUFY1 | SCP2 | 0.720386 | 11 | 0 | 11 |
| RUFY1 | LRRFIP2 | 0.719903 | 11 | 0 | 10 |
For details and further investigation, click here
