PRSS23

 

Full name: serine protease 23 Alias Symbol: SPUVE|SIG13
Type: protein-coding gene Cytoband: 11q14.2
Entrez ID: 11098 HGNC ID: HGNC:14370 Ensembl Gene: ENSG00000150687 OMIM ID: 618376
Drug and gene relationship at DGIdb

 

Expression of PRSS23:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRSS23 11098 202458_at 0.7794 0.3905
GSE20347 PRSS23 11098 202458_at 1.8801 0.0000
GSE23400 PRSS23 11098 202458_at 1.3331 0.0000
GSE26886 PRSS23 11098 202458_at 1.8250 0.0003
GSE29001 PRSS23 11098 202458_at 1.0353 0.0038
GSE38129 PRSS23 11098 202458_at 1.3014 0.0002
GSE45670 PRSS23 11098 202458_at 0.7308 0.1662
GSE53622 PRSS23 11098 39359 0.7123 0.0000
GSE53624 PRSS23 11098 39359 1.1659 0.0000
GSE63941 PRSS23 11098 202458_at -2.0691 0.1335
GSE77861 PRSS23 11098 202458_at 2.6308 0.0016
GSE97050 PRSS23 11098 A_24_P937405 0.4795 0.2681
SRP007169 PRSS23 11098 RNAseq 2.6846 0.0000
SRP008496 PRSS23 11098 RNAseq 3.5268 0.0000
SRP064894 PRSS23 11098 RNAseq 1.5668 0.0000
SRP133303 PRSS23 11098 RNAseq 1.1324 0.0000
SRP159526 PRSS23 11098 RNAseq 1.0651 0.0279
SRP193095 PRSS23 11098 RNAseq 1.5594 0.0000
SRP219564 PRSS23 11098 RNAseq 0.5013 0.5303
TCGA PRSS23 11098 RNAseq -0.1860 0.0910

Upregulated datasets: 13; Downregulated datasets: 0.  

 

Survival by PRSS23 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PRSS23:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRSS23 11098 4 9 17
GSE20123 PRSS23 11098 4 9 17
GSE43470 PRSS23 11098 3 4 36
GSE46452 PRSS23 11098 5 24 30
GSE47630 PRSS23 11098 2 19 19
GSE54993 PRSS23 11098 8 2 60
GSE54994 PRSS23 11098 5 19 29
GSE60625 PRSS23 11098 0 3 8
GSE74703 PRSS23 11098 2 3 31
GSE74704 PRSS23 11098 3 6 11
TCGA PRSS23 11098 16 38 42

Total number of gains: 52; Total number of losses: 136; Total Number of normals: 300.  

 

Somatic mutations of PRSS23:

 

Generating mutation plots.

 

Highly correlated genes for PRSS23:

 

Showing top 20/1462 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRSS23LRRC8C0.783763303
PRSS23SMCR80.761609303
PRSS23A4GALT0.760696303
PRSS23TGFBI0.75755413012
PRSS23FCGR3A0.748884303
PRSS23ATP11C0.744146404
PRSS23FKBP90.74165611011
PRSS23WDR810.740504303
PRSS23SLC39A140.74032712011
PRSS23CELF10.732686303
PRSS23FAP0.73231911010
PRSS23COL5A20.72460813012
PRSS23LGALS10.72267212012
PRSS23TRAM20.72029812012
PRSS23GPX80.72002808
PRSS23AHR0.71912711011
PRSS23AMIGO20.71806412011
PRSS23LPCAT10.71786111011
PRSS23LOXL20.71760912011
PRSS23CHST150.71076312012

For details and further investigation, click here