| Full name: arginine and serine rich coiled-coil 1 | Alias Symbol: MGC12197|BM-011|SRrp53|SFRS21 | ||
| Type: protein-coding gene | Cytoband: 3q25.32 | ||
| Entrez ID: 51319 | HGNC ID: HGNC:24152 | Ensembl Gene: ENSG00000174891 | OMIM ID: 613352 |
| Drug and gene relationship at DGIdb | |||
Expression of RSRC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RSRC1 | 51319 | 1555501_s_at | 1.1866 | 0.0409 | |
| GSE20347 | RSRC1 | 51319 | 219507_at | 1.2724 | 0.0000 | |
| GSE23400 | RSRC1 | 51319 | 219507_at | 0.7063 | 0.0000 | |
| GSE26886 | RSRC1 | 51319 | 1555501_s_at | 1.4213 | 0.0000 | |
| GSE29001 | RSRC1 | 51319 | 219507_at | 1.3505 | 0.0133 | |
| GSE38129 | RSRC1 | 51319 | 219507_at | 1.0634 | 0.0008 | |
| GSE45670 | RSRC1 | 51319 | 1555501_s_at | 1.3176 | 0.0000 | |
| GSE53622 | RSRC1 | 51319 | 8610 | 0.6416 | 0.0000 | |
| GSE53624 | RSRC1 | 51319 | 8610 | 1.0785 | 0.0000 | |
| GSE63941 | RSRC1 | 51319 | 1555501_s_at | 1.4103 | 0.0215 | |
| GSE77861 | RSRC1 | 51319 | 1555501_s_at | 1.2223 | 0.0041 | |
| GSE97050 | RSRC1 | 51319 | A_32_P34589 | 0.1834 | 0.5057 | |
| SRP007169 | RSRC1 | 51319 | RNAseq | 0.5804 | 0.1350 | |
| SRP008496 | RSRC1 | 51319 | RNAseq | 1.0844 | 0.0002 | |
| SRP064894 | RSRC1 | 51319 | RNAseq | 0.8632 | 0.0000 | |
| SRP133303 | RSRC1 | 51319 | RNAseq | 1.2022 | 0.0000 | |
| SRP159526 | RSRC1 | 51319 | RNAseq | 1.3522 | 0.0000 | |
| SRP193095 | RSRC1 | 51319 | RNAseq | 0.9260 | 0.0000 | |
| SRP219564 | RSRC1 | 51319 | RNAseq | 1.1079 | 0.0171 | |
| TCGA | RSRC1 | 51319 | RNAseq | 0.3603 | 0.0000 |
Upregulated datasets: 13; Downregulated datasets: 0.
Survival by RSRC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RSRC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RSRC1 | 51319 | 22 | 0 | 8 | |
| GSE20123 | RSRC1 | 51319 | 22 | 0 | 8 | |
| GSE43470 | RSRC1 | 51319 | 23 | 0 | 20 | |
| GSE46452 | RSRC1 | 51319 | 18 | 2 | 39 | |
| GSE47630 | RSRC1 | 51319 | 18 | 4 | 18 | |
| GSE54993 | RSRC1 | 51319 | 1 | 11 | 58 | |
| GSE54994 | RSRC1 | 51319 | 38 | 1 | 14 | |
| GSE60625 | RSRC1 | 51319 | 0 | 6 | 5 | |
| GSE74703 | RSRC1 | 51319 | 20 | 0 | 16 | |
| GSE74704 | RSRC1 | 51319 | 14 | 0 | 6 | |
| TCGA | RSRC1 | 51319 | 75 | 1 | 20 |
Total number of gains: 251; Total number of losses: 25; Total Number of normals: 212.
Somatic mutations of RSRC1:
Generating mutation plots.
Highly correlated genes for RSRC1:
Showing top 20/1817 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RSRC1 | LRRC58 | 0.833331 | 5 | 0 | 5 |
| RSRC1 | PRR12 | 0.795394 | 3 | 0 | 3 |
| RSRC1 | A4GALT | 0.795103 | 3 | 0 | 3 |
| RSRC1 | ALKBH6 | 0.774797 | 5 | 0 | 5 |
| RSRC1 | INPP5B | 0.766101 | 4 | 0 | 3 |
| RSRC1 | MRPL47 | 0.757654 | 8 | 0 | 7 |
| RSRC1 | WDR4 | 0.755246 | 4 | 0 | 3 |
| RSRC1 | IRF2BP2 | 0.75508 | 3 | 0 | 3 |
| RSRC1 | U2SURP | 0.750784 | 10 | 0 | 9 |
| RSRC1 | KLF10 | 0.747928 | 3 | 0 | 3 |
| RSRC1 | DNAJB11 | 0.746877 | 6 | 0 | 6 |
| RSRC1 | WDR54 | 0.742582 | 6 | 0 | 6 |
| RSRC1 | YWHAG | 0.737993 | 6 | 0 | 5 |
| RSRC1 | ATR | 0.737313 | 10 | 0 | 10 |
| RSRC1 | PPP1R9B | 0.736806 | 3 | 0 | 3 |
| RSRC1 | ATXN1L | 0.735973 | 3 | 0 | 3 |
| RSRC1 | ACTL6A | 0.733041 | 12 | 0 | 11 |
| RSRC1 | USP36 | 0.732377 | 4 | 0 | 3 |
| RSRC1 | WDR81 | 0.72977 | 4 | 0 | 4 |
| RSRC1 | AURKAIP1 | 0.724289 | 4 | 0 | 3 |
For details and further investigation, click here
