| Full name: propionyl-CoA carboxylase subunit beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q22.3 | ||
| Entrez ID: 5096 | HGNC ID: HGNC:8654 | Ensembl Gene: ENSG00000114054 | OMIM ID: 232050 |
| Drug and gene relationship at DGIdb | |||
Expression of PCCB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCCB | 5096 | 212694_s_at | 0.4610 | 0.1521 | |
| GSE20347 | PCCB | 5096 | 212694_s_at | 0.5461 | 0.0005 | |
| GSE23400 | PCCB | 5096 | 212694_s_at | 0.4557 | 0.0000 | |
| GSE26886 | PCCB | 5096 | 212694_s_at | -0.3715 | 0.0847 | |
| GSE29001 | PCCB | 5096 | 212694_s_at | 0.4551 | 0.2693 | |
| GSE38129 | PCCB | 5096 | 212694_s_at | 0.4989 | 0.0002 | |
| GSE45670 | PCCB | 5096 | 212694_s_at | 0.3210 | 0.1950 | |
| GSE53622 | PCCB | 5096 | 16474 | 0.0806 | 0.4423 | |
| GSE53624 | PCCB | 5096 | 16474 | 0.2244 | 0.0803 | |
| GSE63941 | PCCB | 5096 | 212694_s_at | 0.7685 | 0.2104 | |
| GSE77861 | PCCB | 5096 | 212694_s_at | 0.0853 | 0.8384 | |
| GSE97050 | PCCB | 5096 | A_24_P302802 | -0.0634 | 0.8415 | |
| SRP007169 | PCCB | 5096 | RNAseq | 0.6590 | 0.0357 | |
| SRP008496 | PCCB | 5096 | RNAseq | 0.3792 | 0.1617 | |
| SRP064894 | PCCB | 5096 | RNAseq | 0.6656 | 0.0092 | |
| SRP133303 | PCCB | 5096 | RNAseq | 0.1545 | 0.4106 | |
| SRP159526 | PCCB | 5096 | RNAseq | 0.8001 | 0.0360 | |
| SRP193095 | PCCB | 5096 | RNAseq | -0.1416 | 0.3087 | |
| SRP219564 | PCCB | 5096 | RNAseq | -0.1573 | 0.6853 | |
| TCGA | PCCB | 5096 | RNAseq | -0.0378 | 0.4986 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCCB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCCB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCCB | 5096 | 16 | 0 | 14 | |
| GSE20123 | PCCB | 5096 | 16 | 0 | 14 | |
| GSE43470 | PCCB | 5096 | 22 | 0 | 21 | |
| GSE46452 | PCCB | 5096 | 15 | 4 | 40 | |
| GSE47630 | PCCB | 5096 | 18 | 3 | 19 | |
| GSE54993 | PCCB | 5096 | 2 | 8 | 60 | |
| GSE54994 | PCCB | 5096 | 32 | 1 | 20 | |
| GSE60625 | PCCB | 5096 | 0 | 6 | 5 | |
| GSE74703 | PCCB | 5096 | 19 | 0 | 17 | |
| GSE74704 | PCCB | 5096 | 11 | 0 | 9 | |
| TCGA | PCCB | 5096 | 58 | 5 | 33 |
Total number of gains: 209; Total number of losses: 27; Total Number of normals: 252.
Somatic mutations of PCCB:
Generating mutation plots.
Highly correlated genes for PCCB:
Showing top 20/615 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCCB | USP36 | 0.750809 | 3 | 0 | 3 |
| PCCB | XRN1 | 0.722508 | 3 | 0 | 3 |
| PCCB | XXYLT1 | 0.720213 | 3 | 0 | 3 |
| PCCB | DGKQ | 0.704279 | 3 | 0 | 3 |
| PCCB | PCNT | 0.696127 | 3 | 0 | 3 |
| PCCB | CENPBD1 | 0.694513 | 3 | 0 | 3 |
| PCCB | MRPS11 | 0.68943 | 4 | 0 | 3 |
| PCCB | ADO | 0.688827 | 4 | 0 | 3 |
| PCCB | LTV1 | 0.684899 | 3 | 0 | 3 |
| PCCB | BCKDK | 0.683219 | 3 | 0 | 3 |
| PCCB | NUB1 | 0.683203 | 4 | 0 | 3 |
| PCCB | EMG1 | 0.680379 | 8 | 0 | 8 |
| PCCB | GYS1 | 0.677843 | 3 | 0 | 3 |
| PCCB | SNF8 | 0.674449 | 5 | 0 | 4 |
| PCCB | CLN6 | 0.670031 | 4 | 0 | 3 |
| PCCB | USP14 | 0.666485 | 5 | 0 | 5 |
| PCCB | PPP1R10 | 0.665347 | 4 | 0 | 3 |
| PCCB | CNBP | 0.662936 | 9 | 0 | 8 |
| PCCB | FBXW8 | 0.661703 | 3 | 0 | 3 |
| PCCB | PSMD3 | 0.659577 | 7 | 0 | 6 |
For details and further investigation, click here
