TBC1D31

 

Full name: TBC1 domain family member 31 Alias Symbol: MGC21654|Gm85
Type: protein-coding gene Cytoband: 8q24.13
Entrez ID: 93594 HGNC ID: HGNC:30888 Ensembl Gene: ENSG00000156787 OMIM ID: 
Screen Evidence:

 

Expression of TBC1D31:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TBC1D31 93594 214061_at 1.2882 0.0396
GSE20347 TBC1D31 93594 214061_at 1.1958 0.0000
GSE23400 TBC1D31 93594 214061_at 0.4586 0.0000
GSE26886 TBC1D31 93594 214061_at 0.9384 0.0004
GSE29001 TBC1D31 93594 214061_at 1.2522 0.0006
GSE38129 TBC1D31 93594 214061_at 1.1987 0.0000
GSE45670 TBC1D31 93594 214061_at 1.0315 0.0000
GSE53622 TBC1D31 93594 107825 0.9079 0.0000
GSE53624 TBC1D31 93594 58430 1.1362 0.0000
GSE63941 TBC1D31 93594 214061_at 0.7366 0.2181
GSE77861 TBC1D31 93594 214061_at 0.8363 0.0213
SRP007169 TBC1D31 93594 RNAseq 0.0234 0.9501
SRP008496 TBC1D31 93594 RNAseq 0.4252 0.2021
SRP064894 TBC1D31 93594 RNAseq 1.4918 0.0000
SRP133303 TBC1D31 93594 RNAseq 0.8735 0.0000
SRP159526 TBC1D31 93594 RNAseq 0.9235 0.0024
SRP193095 TBC1D31 93594 RNAseq 0.5862 0.0000
SRP219564 TBC1D31 93594 RNAseq 1.6191 0.0015

Upregulated datasets: 8; Downregulated datasets: 0.  

 

Survival by TBC1D31 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of TBC1D31:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TBC1D31 93594 19 1 10
GSE20123 TBC1D31 93594 20 1 9
GSE43470 TBC1D31 93594 22 0 21
GSE46452 TBC1D31 93594 27 0 32
GSE47630 TBC1D31 93594 24 0 16
GSE54993 TBC1D31 93594 0 21 49
GSE54994 TBC1D31 93594 37 1 15
GSE60625 TBC1D31 93594 0 4 7
GSE74703 TBC1D31 93594 19 0 17
GSE74704 TBC1D31 93594 13 1 6
TCGA TBC1D31 93594 67 1 28

Total number of gains: 248; Total number of losses: 30; Total Number of normals: 210.  

 

Somatic mutations of TBC1D31:

 

Generating mutation plots.

 

Highly correlated genes for TBC1D31:

 

Showing top 20/1834 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TBC1D31DSCC10.800012909
TBC1D31GNPNAT10.798652303
TBC1D31MTERF30.794604909
TBC1D31LRRC580.789359303
TBC1D31MTBP0.7877504
TBC1D31ATAD20.77773711010
TBC1D31NEK20.7761231009
TBC1D31PRKDC0.77267210010
TBC1D31CENPF0.76482711010
TBC1D31UHRF10.762067505
TBC1D31TAF20.76098611011
TBC1D31HOXC90.758269404
TBC1D31MCM40.7554721009
TBC1D31RAD54B0.75393711010
TBC1D31DNMT10.75134910010
TBC1D31FLVCR10.749093606
TBC1D31PTDSS10.74884210010
TBC1D31DPY19L40.74594210010
TBC1D31CEP550.7458361009
TBC1D31TIMELESS0.74503610010

For details and further investigation, click here