| Full name: very low density lipoprotein receptor | Alias Symbol: CARMQ1|CHRMQ1|VLDLRCH | ||
| Type: protein-coding gene | Cytoband: 9p24.2 | ||
| Entrez ID: 7436 | HGNC ID: HGNC:12698 | Ensembl Gene: ENSG00000147852 | OMIM ID: 192977 |
| Drug and gene relationship at DGIdb | |||
Expression of VLDLR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VLDLR | 7436 | 209822_s_at | -1.5421 | 0.0114 | |
| GSE20347 | VLDLR | 7436 | 209822_s_at | -1.4528 | 0.0001 | |
| GSE23400 | VLDLR | 7436 | 209822_s_at | -0.5368 | 0.0000 | |
| GSE26886 | VLDLR | 7436 | 209822_s_at | -3.0715 | 0.0000 | |
| GSE29001 | VLDLR | 7436 | 209822_s_at | -1.2677 | 0.0108 | |
| GSE38129 | VLDLR | 7436 | 209822_s_at | -1.1598 | 0.0000 | |
| GSE45670 | VLDLR | 7436 | 209822_s_at | -0.3702 | 0.2878 | |
| GSE53622 | VLDLR | 7436 | 10811 | -1.0317 | 0.0000 | |
| GSE53624 | VLDLR | 7436 | 10811 | -1.2099 | 0.0000 | |
| GSE63941 | VLDLR | 7436 | 209822_s_at | -2.3675 | 0.0265 | |
| GSE77861 | VLDLR | 7436 | 209822_s_at | -1.4954 | 0.0072 | |
| GSE97050 | VLDLR | 7436 | A_23_P43476 | -0.9378 | 0.0555 | |
| SRP007169 | VLDLR | 7436 | RNAseq | -1.1860 | 0.0475 | |
| SRP008496 | VLDLR | 7436 | RNAseq | -0.8875 | 0.0439 | |
| SRP064894 | VLDLR | 7436 | RNAseq | -0.7254 | 0.0059 | |
| SRP133303 | VLDLR | 7436 | RNAseq | -1.0491 | 0.0001 | |
| SRP159526 | VLDLR | 7436 | RNAseq | -1.2400 | 0.0221 | |
| SRP193095 | VLDLR | 7436 | RNAseq | -1.3228 | 0.0000 | |
| SRP219564 | VLDLR | 7436 | RNAseq | -0.9048 | 0.1236 | |
| TCGA | VLDLR | 7436 | RNAseq | -0.3569 | 0.0042 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by VLDLR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VLDLR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VLDLR | 7436 | 1 | 16 | 13 | |
| GSE20123 | VLDLR | 7436 | 1 | 15 | 14 | |
| GSE43470 | VLDLR | 7436 | 3 | 13 | 27 | |
| GSE46452 | VLDLR | 7436 | 2 | 23 | 34 | |
| GSE47630 | VLDLR | 7436 | 4 | 27 | 9 | |
| GSE54993 | VLDLR | 7436 | 6 | 3 | 61 | |
| GSE54994 | VLDLR | 7436 | 9 | 18 | 26 | |
| GSE60625 | VLDLR | 7436 | 0 | 2 | 9 | |
| GSE74703 | VLDLR | 7436 | 3 | 10 | 23 | |
| GSE74704 | VLDLR | 7436 | 0 | 12 | 8 | |
| TCGA | VLDLR | 7436 | 13 | 52 | 31 |
Total number of gains: 42; Total number of losses: 191; Total Number of normals: 255.
Somatic mutations of VLDLR:
Generating mutation plots.
Highly correlated genes for VLDLR:
Showing top 20/1161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VLDLR | SPAG17 | 0.76115 | 4 | 0 | 4 |
| VLDLR | SPNS2 | 0.745391 | 4 | 0 | 4 |
| VLDLR | KALRN | 0.734144 | 6 | 0 | 6 |
| VLDLR | VSIG10L | 0.732421 | 6 | 0 | 6 |
| VLDLR | SFTA2 | 0.726354 | 4 | 0 | 4 |
| VLDLR | FCHO2 | 0.725773 | 7 | 0 | 7 |
| VLDLR | KANK1 | 0.720427 | 13 | 0 | 12 |
| VLDLR | BNIPL | 0.715141 | 6 | 0 | 6 |
| VLDLR | SMIM5 | 0.709789 | 6 | 0 | 6 |
| VLDLR | CYSRT1 | 0.70286 | 6 | 0 | 6 |
| VLDLR | EIF4E3 | 0.702736 | 7 | 0 | 6 |
| VLDLR | MAB21L3 | 0.699637 | 6 | 0 | 6 |
| VLDLR | ANKRD37 | 0.697607 | 6 | 0 | 6 |
| VLDLR | MGLL | 0.696953 | 11 | 0 | 10 |
| VLDLR | A2ML1 | 0.68684 | 6 | 0 | 6 |
| VLDLR | C5orf66-AS1 | 0.685925 | 6 | 0 | 6 |
| VLDLR | AK3 | 0.685449 | 8 | 0 | 8 |
| VLDLR | CYYR1 | 0.682777 | 4 | 0 | 3 |
| VLDLR | ATG9B | 0.682688 | 6 | 0 | 6 |
| VLDLR | MIR210HG | 0.67806 | 6 | 0 | 5 |
For details and further investigation, click here
