| Full name: KN motif and ankyrin repeat domains 1 | Alias Symbol: KIAA0172|KANK | ||
| Type: protein-coding gene | Cytoband: 9p24.3 | ||
| Entrez ID: 23189 | HGNC ID: HGNC:19309 | Ensembl Gene: ENSG00000107104 | OMIM ID: 607704 |
| Drug and gene relationship at DGIdb | |||
Expression of KANK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KANK1 | 23189 | 213005_s_at | -1.8246 | 0.0154 | |
| GSE20347 | KANK1 | 23189 | 213005_s_at | -2.1324 | 0.0000 | |
| GSE23400 | KANK1 | 23189 | 213005_s_at | -1.5150 | 0.0000 | |
| GSE26886 | KANK1 | 23189 | 213005_s_at | -2.4179 | 0.0000 | |
| GSE29001 | KANK1 | 23189 | 213005_s_at | -1.2345 | 0.0006 | |
| GSE38129 | KANK1 | 23189 | 213005_s_at | -1.9271 | 0.0000 | |
| GSE45670 | KANK1 | 23189 | 213005_s_at | -1.1551 | 0.0004 | |
| GSE53622 | KANK1 | 23189 | 48199 | -1.9205 | 0.0000 | |
| GSE53624 | KANK1 | 23189 | 48199 | -1.9568 | 0.0000 | |
| GSE63941 | KANK1 | 23189 | 213005_s_at | -2.4577 | 0.0321 | |
| GSE77861 | KANK1 | 23189 | 213005_s_at | -1.4157 | 0.0305 | |
| GSE97050 | KANK1 | 23189 | A_23_P500130 | -1.7682 | 0.0465 | |
| SRP007169 | KANK1 | 23189 | RNAseq | -2.2967 | 0.0001 | |
| SRP008496 | KANK1 | 23189 | RNAseq | -2.1393 | 0.0000 | |
| SRP064894 | KANK1 | 23189 | RNAseq | -1.6285 | 0.0000 | |
| SRP133303 | KANK1 | 23189 | RNAseq | -1.9269 | 0.0000 | |
| SRP159526 | KANK1 | 23189 | RNAseq | -2.5401 | 0.0000 | |
| SRP193095 | KANK1 | 23189 | RNAseq | -1.8268 | 0.0000 | |
| SRP219564 | KANK1 | 23189 | RNAseq | -1.4437 | 0.0005 | |
| TCGA | KANK1 | 23189 | RNAseq | -0.1936 | 0.0521 |
Upregulated datasets: 0; Downregulated datasets: 19.
Survival by KANK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KANK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KANK1 | 23189 | 1 | 16 | 13 | |
| GSE20123 | KANK1 | 23189 | 1 | 15 | 14 | |
| GSE43470 | KANK1 | 23189 | 3 | 16 | 24 | |
| GSE46452 | KANK1 | 23189 | 2 | 23 | 34 | |
| GSE47630 | KANK1 | 23189 | 4 | 27 | 9 | |
| GSE54993 | KANK1 | 23189 | 6 | 3 | 61 | |
| GSE54994 | KANK1 | 23189 | 9 | 18 | 26 | |
| GSE60625 | KANK1 | 23189 | 0 | 2 | 9 | |
| GSE74703 | KANK1 | 23189 | 3 | 12 | 21 | |
| GSE74704 | KANK1 | 23189 | 0 | 12 | 8 | |
| TCGA | KANK1 | 23189 | 13 | 51 | 32 |
Total number of gains: 42; Total number of losses: 195; Total Number of normals: 251.
Somatic mutations of KANK1:
Generating mutation plots.
Highly correlated genes for KANK1:
Showing top 20/1741 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KANK1 | GBP6 | 0.856613 | 4 | 0 | 4 |
| KANK1 | SNORA68 | 0.841216 | 4 | 0 | 4 |
| KANK1 | CAST | 0.825975 | 11 | 0 | 11 |
| KANK1 | HPGD | 0.824888 | 11 | 0 | 11 |
| KANK1 | EMP1 | 0.822323 | 10 | 0 | 10 |
| KANK1 | SH3BGRL2 | 0.822129 | 7 | 0 | 7 |
| KANK1 | A2ML1 | 0.815742 | 6 | 0 | 6 |
| KANK1 | CYSRT1 | 0.815188 | 6 | 0 | 6 |
| KANK1 | VSIG10L | 0.815074 | 6 | 0 | 6 |
| KANK1 | MGLL | 0.812518 | 12 | 0 | 12 |
| KANK1 | GPD1L | 0.811406 | 11 | 0 | 11 |
| KANK1 | SFTA2 | 0.808314 | 4 | 0 | 4 |
| KANK1 | FAM214A | 0.808115 | 6 | 0 | 6 |
| KANK1 | SPINK7 | 0.805918 | 6 | 0 | 6 |
| KANK1 | SCNN1B | 0.804299 | 10 | 0 | 10 |
| KANK1 | MAL | 0.802575 | 10 | 0 | 10 |
| KANK1 | TMPRSS11B | 0.797911 | 6 | 0 | 6 |
| KANK1 | ZNF662 | 0.797644 | 7 | 0 | 7 |
| KANK1 | CSTB | 0.797396 | 10 | 0 | 10 |
| KANK1 | ACOX3 | 0.794725 | 10 | 0 | 10 |
For details and further investigation, click here
