| Full name: RUN and FYVE domain containing 2 | Alias Symbol: RABIP4R|FLJ10063|KIAA1537|ZFYVE13 | ||
| Type: protein-coding gene | Cytoband: 10q21.3 | ||
| Entrez ID: 55680 | HGNC ID: HGNC:19761 | Ensembl Gene: ENSG00000204130 | OMIM ID: 610328 |
| Drug and gene relationship at DGIdb | |||
Expression of RUFY2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RUFY2 | 55680 | 219957_at | -0.1626 | 0.9276 | |
| GSE20347 | RUFY2 | 55680 | 219957_at | -0.7542 | 0.0060 | |
| GSE23400 | RUFY2 | 55680 | 219957_at | -0.6300 | 0.0000 | |
| GSE29001 | RUFY2 | 55680 | 219957_at | -0.7516 | 0.0034 | |
| GSE38129 | RUFY2 | 55680 | 219957_at | -0.7987 | 0.0005 | |
| GSE45670 | RUFY2 | 55680 | 219957_at | -0.7521 | 0.0001 | |
| GSE53622 | RUFY2 | 55680 | 10701 | 0.1844 | 0.0016 | |
| GSE53624 | RUFY2 | 55680 | 10701 | 0.3228 | 0.0004 | |
| GSE97050 | RUFY2 | 55680 | A_24_P941708 | 0.1436 | 0.4980 | |
| SRP007169 | RUFY2 | 55680 | RNAseq | -0.8467 | 0.0848 | |
| SRP008496 | RUFY2 | 55680 | RNAseq | -0.2742 | 0.3366 | |
| SRP064894 | RUFY2 | 55680 | RNAseq | -0.5084 | 0.0470 | |
| SRP133303 | RUFY2 | 55680 | RNAseq | -0.1495 | 0.2245 | |
| SRP159526 | RUFY2 | 55680 | RNAseq | -0.3033 | 0.3795 | |
| SRP193095 | RUFY2 | 55680 | RNAseq | -0.2893 | 0.0117 | |
| SRP219564 | RUFY2 | 55680 | RNAseq | -0.4300 | 0.0545 | |
| TCGA | RUFY2 | 55680 | RNAseq | -0.1116 | 0.0534 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RUFY2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RUFY2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RUFY2 | 55680 | 3 | 5 | 22 | |
| GSE20123 | RUFY2 | 55680 | 3 | 4 | 23 | |
| GSE43470 | RUFY2 | 55680 | 1 | 8 | 34 | |
| GSE46452 | RUFY2 | 55680 | 0 | 11 | 48 | |
| GSE47630 | RUFY2 | 55680 | 2 | 14 | 24 | |
| GSE54993 | RUFY2 | 55680 | 8 | 0 | 62 | |
| GSE54994 | RUFY2 | 55680 | 2 | 12 | 39 | |
| GSE60625 | RUFY2 | 55680 | 0 | 0 | 11 | |
| GSE74703 | RUFY2 | 55680 | 1 | 5 | 30 | |
| GSE74704 | RUFY2 | 55680 | 1 | 2 | 17 | |
| TCGA | RUFY2 | 55680 | 10 | 22 | 64 |
Total number of gains: 31; Total number of losses: 83; Total Number of normals: 374.
Somatic mutations of RUFY2:
Generating mutation plots.
Highly correlated genes for RUFY2:
Showing top 20/140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RUFY2 | VPS13B | 0.722846 | 3 | 0 | 3 |
| RUFY2 | PRKAB1 | 0.703281 | 3 | 0 | 3 |
| RUFY2 | SRFBP1 | 0.698793 | 3 | 0 | 3 |
| RUFY2 | FAF2 | 0.697878 | 3 | 0 | 3 |
| RUFY2 | EIF3I | 0.693855 | 3 | 0 | 3 |
| RUFY2 | CRK | 0.682742 | 3 | 0 | 3 |
| RUFY2 | CLK3 | 0.677141 | 3 | 0 | 3 |
| RUFY2 | MB21D2 | 0.673922 | 3 | 0 | 3 |
| RUFY2 | SCAF4 | 0.67274 | 3 | 0 | 3 |
| RUFY2 | AKAP17A | 0.669873 | 3 | 0 | 3 |
| RUFY2 | OPLAH | 0.665283 | 3 | 0 | 3 |
| RUFY2 | EIF2B4 | 0.656739 | 4 | 0 | 3 |
| RUFY2 | ILKAP | 0.656687 | 4 | 0 | 3 |
| RUFY2 | CD59 | 0.653401 | 4 | 0 | 3 |
| RUFY2 | SPTLC3 | 0.652136 | 4 | 0 | 3 |
| RUFY2 | PODNL1 | 0.64611 | 4 | 0 | 3 |
| RUFY2 | ANKRD50 | 0.645154 | 4 | 0 | 3 |
| RUFY2 | EAF1 | 0.640806 | 4 | 0 | 3 |
| RUFY2 | ZFC3H1 | 0.637682 | 4 | 0 | 4 |
| RUFY2 | ZFP36L1 | 0.636936 | 4 | 0 | 4 |
For details and further investigation, click here
