| Full name: SET binding factor 2 | Alias Symbol: KIAA1766|MTMR13|DENND7B | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 81846 | HGNC ID: HGNC:2135 | Ensembl Gene: ENSG00000133812 | OMIM ID: 607697 |
| Drug and gene relationship at DGIdb | |||
Expression of SBF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SBF2 | 81846 | 226169_at | -0.6192 | 0.2773 | |
| GSE26886 | SBF2 | 81846 | 226169_at | 0.3800 | 0.1622 | |
| GSE45670 | SBF2 | 81846 | 226169_at | -0.6327 | 0.0000 | |
| GSE53622 | SBF2 | 81846 | 105154 | -0.3847 | 0.0001 | |
| GSE53624 | SBF2 | 81846 | 105154 | -0.4379 | 0.0000 | |
| GSE63941 | SBF2 | 81846 | 226169_at | -0.9116 | 0.0500 | |
| GSE77861 | SBF2 | 81846 | 226169_at | -0.3263 | 0.3472 | |
| GSE97050 | SBF2 | 81846 | A_23_P419795 | -0.3818 | 0.1506 | |
| SRP007169 | SBF2 | 81846 | RNAseq | 0.0677 | 0.8188 | |
| SRP008496 | SBF2 | 81846 | RNAseq | 0.2103 | 0.1691 | |
| SRP064894 | SBF2 | 81846 | RNAseq | -0.3747 | 0.1885 | |
| SRP133303 | SBF2 | 81846 | RNAseq | -0.0654 | 0.6710 | |
| SRP159526 | SBF2 | 81846 | RNAseq | -0.5323 | 0.0427 | |
| SRP193095 | SBF2 | 81846 | RNAseq | -0.0484 | 0.5897 | |
| SRP219564 | SBF2 | 81846 | RNAseq | -0.4386 | 0.2404 | |
| TCGA | SBF2 | 81846 | RNAseq | -0.1749 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SBF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SBF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SBF2 | 81846 | 0 | 9 | 21 | |
| GSE20123 | SBF2 | 81846 | 0 | 10 | 20 | |
| GSE43470 | SBF2 | 81846 | 1 | 6 | 36 | |
| GSE46452 | SBF2 | 81846 | 7 | 5 | 47 | |
| GSE47630 | SBF2 | 81846 | 3 | 11 | 26 | |
| GSE54993 | SBF2 | 81846 | 3 | 1 | 66 | |
| GSE54994 | SBF2 | 81846 | 3 | 12 | 38 | |
| GSE60625 | SBF2 | 81846 | 0 | 0 | 11 | |
| GSE74703 | SBF2 | 81846 | 1 | 4 | 31 | |
| GSE74704 | SBF2 | 81846 | 0 | 7 | 13 | |
| TCGA | SBF2 | 81846 | 12 | 34 | 50 |
Total number of gains: 30; Total number of losses: 99; Total Number of normals: 359.
Somatic mutations of SBF2:
Generating mutation plots.
Highly correlated genes for SBF2:
Showing top 20/614 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SBF2 | HOXA3 | 0.830581 | 3 | 0 | 3 |
| SBF2 | CCDC82 | 0.763634 | 3 | 0 | 3 |
| SBF2 | CRIM1 | 0.762833 | 3 | 0 | 3 |
| SBF2 | CAPN2 | 0.762637 | 3 | 0 | 3 |
| SBF2 | TRIM44 | 0.752869 | 4 | 0 | 4 |
| SBF2 | TCF12 | 0.74969 | 3 | 0 | 3 |
| SBF2 | EBAG9 | 0.748928 | 3 | 0 | 3 |
| SBF2 | ZNF655 | 0.748211 | 3 | 0 | 3 |
| SBF2 | ROCK1 | 0.746618 | 4 | 0 | 4 |
| SBF2 | RBBP6 | 0.746073 | 3 | 0 | 3 |
| SBF2 | KAT5 | 0.738931 | 3 | 0 | 3 |
| SBF2 | ENDOD1 | 0.738605 | 3 | 0 | 3 |
| SBF2 | LYRM7 | 0.736849 | 3 | 0 | 3 |
| SBF2 | ZRANB1 | 0.725073 | 3 | 0 | 3 |
| SBF2 | SRI | 0.723379 | 3 | 0 | 3 |
| SBF2 | NIPSNAP3B | 0.716615 | 3 | 0 | 3 |
| SBF2 | WDFY3 | 0.71472 | 4 | 0 | 4 |
| SBF2 | TMTC1 | 0.711652 | 3 | 0 | 3 |
| SBF2 | UGP2 | 0.711061 | 4 | 0 | 3 |
| SBF2 | ZNF140 | 0.710132 | 3 | 0 | 3 |
For details and further investigation, click here
