| Full name: growth hormone regulated TBC protein 1 | Alias Symbol: FLJ22474|TBC1D6 | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 79774 | HGNC ID: HGNC:20310 | Ensembl Gene: ENSG00000139835 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GRTP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRTP1 | 79774 | 229377_at | -0.0830 | 0.9381 | |
| GSE20347 | GRTP1 | 79774 | 206712_at | 0.2453 | 0.3822 | |
| GSE23400 | GRTP1 | 79774 | 206712_at | -0.0762 | 0.0223 | |
| GSE26886 | GRTP1 | 79774 | 229377_at | 0.1996 | 0.6831 | |
| GSE29001 | GRTP1 | 79774 | 206712_at | -0.0627 | 0.7069 | |
| GSE38129 | GRTP1 | 79774 | 206712_at | 0.2638 | 0.2134 | |
| GSE45670 | GRTP1 | 79774 | 229377_at | 0.1119 | 0.7584 | |
| GSE53622 | GRTP1 | 79774 | 57141 | -0.2932 | 0.0536 | |
| GSE53624 | GRTP1 | 79774 | 57141 | -0.4778 | 0.0045 | |
| GSE63941 | GRTP1 | 79774 | 229377_at | 3.9242 | 0.0004 | |
| GSE77861 | GRTP1 | 79774 | 229377_at | -0.2909 | 0.6167 | |
| GSE97050 | GRTP1 | 79774 | A_24_P135748 | -0.0971 | 0.8337 | |
| SRP007169 | GRTP1 | 79774 | RNAseq | -1.0024 | 0.1402 | |
| SRP008496 | GRTP1 | 79774 | RNAseq | -1.0675 | 0.0267 | |
| SRP064894 | GRTP1 | 79774 | RNAseq | -0.4674 | 0.1193 | |
| SRP133303 | GRTP1 | 79774 | RNAseq | -0.3895 | 0.1545 | |
| SRP159526 | GRTP1 | 79774 | RNAseq | -0.4261 | 0.3239 | |
| SRP193095 | GRTP1 | 79774 | RNAseq | -0.4456 | 0.0015 | |
| SRP219564 | GRTP1 | 79774 | RNAseq | 0.0870 | 0.8981 | |
| TCGA | GRTP1 | 79774 | RNAseq | 0.1113 | 0.3367 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by GRTP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRTP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRTP1 | 79774 | 7 | 12 | 11 | |
| GSE20123 | GRTP1 | 79774 | 7 | 11 | 12 | |
| GSE43470 | GRTP1 | 79774 | 4 | 14 | 25 | |
| GSE46452 | GRTP1 | 79774 | 3 | 31 | 25 | |
| GSE47630 | GRTP1 | 79774 | 3 | 26 | 11 | |
| GSE54993 | GRTP1 | 79774 | 11 | 4 | 55 | |
| GSE54994 | GRTP1 | 79774 | 9 | 10 | 34 | |
| GSE60625 | GRTP1 | 79774 | 0 | 3 | 8 | |
| GSE74703 | GRTP1 | 79774 | 3 | 11 | 22 | |
| GSE74704 | GRTP1 | 79774 | 4 | 9 | 7 | |
| TCGA | GRTP1 | 79774 | 21 | 31 | 44 |
Total number of gains: 72; Total number of losses: 162; Total Number of normals: 254.
Somatic mutations of GRTP1:
Generating mutation plots.
Highly correlated genes for GRTP1:
Showing top 20/65 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRTP1 | MCF2L | 0.715859 | 4 | 0 | 4 |
| GRTP1 | RASSF6 | 0.676403 | 3 | 0 | 3 |
| GRTP1 | BAZ2A | 0.662357 | 3 | 0 | 3 |
| GRTP1 | PAN3 | 0.650838 | 4 | 0 | 3 |
| GRTP1 | CC2D1A | 0.647712 | 4 | 0 | 4 |
| GRTP1 | EGFR | 0.639091 | 3 | 0 | 3 |
| GRTP1 | PLEKHH1 | 0.635549 | 4 | 0 | 3 |
| GRTP1 | RAD9A | 0.632785 | 4 | 0 | 4 |
| GRTP1 | SLC25A16 | 0.632527 | 4 | 0 | 4 |
| GRTP1 | VWDE | 0.62486 | 4 | 0 | 4 |
| GRTP1 | N4BP2L2 | 0.614593 | 4 | 0 | 4 |
| GRTP1 | FAM185A | 0.612811 | 3 | 0 | 3 |
| GRTP1 | ASH1L | 0.611745 | 3 | 0 | 3 |
| GRTP1 | CKAP2 | 0.604718 | 4 | 0 | 4 |
| GRTP1 | CUL4A | 0.604235 | 8 | 0 | 6 |
| GRTP1 | PRKCZ | 0.602628 | 4 | 0 | 3 |
| GRTP1 | ACP6 | 0.598718 | 4 | 0 | 3 |
| GRTP1 | CBFA2T2 | 0.596736 | 3 | 0 | 3 |
| GRTP1 | NPNT | 0.592211 | 3 | 0 | 3 |
| GRTP1 | TNFSF10 | 0.589162 | 3 | 0 | 3 |
For details and further investigation, click here
