| Full name: actin related protein 3B | Alias Symbol: ARP11|ARP3beta | ||
| Type: protein-coding gene | Cytoband: 7q36.1-q36.2 | ||
| Entrez ID: 57180 | HGNC ID: HGNC:17256 | Ensembl Gene: ENSG00000133627 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ACTR3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTR3B | 57180 | 1555487_a_at | 0.3253 | 0.5842 | |
| GSE20347 | ACTR3B | 57180 | 218868_at | 0.5789 | 0.0000 | |
| GSE23400 | ACTR3B | 57180 | 218868_at | 0.2508 | 0.0000 | |
| GSE26886 | ACTR3B | 57180 | 1555487_a_at | 0.4101 | 0.0257 | |
| GSE29001 | ACTR3B | 57180 | 218868_at | 0.5320 | 0.0151 | |
| GSE38129 | ACTR3B | 57180 | 218868_at | 0.6711 | 0.0000 | |
| GSE45670 | ACTR3B | 57180 | 218868_at | 0.5005 | 0.0506 | |
| GSE53622 | ACTR3B | 57180 | 62878 | -0.0465 | 0.6210 | |
| GSE53624 | ACTR3B | 57180 | 62878 | -0.4592 | 0.0000 | |
| GSE63941 | ACTR3B | 57180 | 1555487_a_at | 1.4832 | 0.0018 | |
| GSE77861 | ACTR3B | 57180 | 1555487_a_at | 0.1694 | 0.1521 | |
| GSE97050 | ACTR3B | 57180 | A_23_P123193 | -0.0889 | 0.7076 | |
| SRP007169 | ACTR3B | 57180 | RNAseq | 0.6689 | 0.1007 | |
| SRP008496 | ACTR3B | 57180 | RNAseq | 1.0004 | 0.0020 | |
| SRP064894 | ACTR3B | 57180 | RNAseq | 0.3686 | 0.0208 | |
| SRP133303 | ACTR3B | 57180 | RNAseq | 0.3200 | 0.0552 | |
| SRP159526 | ACTR3B | 57180 | RNAseq | 0.9320 | 0.0029 | |
| SRP193095 | ACTR3B | 57180 | RNAseq | 0.4459 | 0.0028 | |
| SRP219564 | ACTR3B | 57180 | RNAseq | 0.4015 | 0.3109 | |
| TCGA | ACTR3B | 57180 | RNAseq | 0.0276 | 0.7967 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ACTR3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTR3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTR3B | 57180 | 2 | 4 | 24 | |
| GSE20123 | ACTR3B | 57180 | 2 | 4 | 24 | |
| GSE43470 | ACTR3B | 57180 | 3 | 4 | 36 | |
| GSE46452 | ACTR3B | 57180 | 7 | 2 | 50 | |
| GSE47630 | ACTR3B | 57180 | 6 | 9 | 25 | |
| GSE54993 | ACTR3B | 57180 | 3 | 3 | 64 | |
| GSE54994 | ACTR3B | 57180 | 6 | 8 | 39 | |
| GSE60625 | ACTR3B | 57180 | 0 | 0 | 11 | |
| GSE74703 | ACTR3B | 57180 | 2 | 4 | 30 | |
| GSE74704 | ACTR3B | 57180 | 1 | 4 | 15 | |
| TCGA | ACTR3B | 57180 | 26 | 27 | 43 |
Total number of gains: 58; Total number of losses: 69; Total Number of normals: 361.
Somatic mutations of ACTR3B:
Generating mutation plots.
Highly correlated genes for ACTR3B:
Showing top 20/306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTR3B | ALX1 | 0.858056 | 3 | 0 | 3 |
| ACTR3B | MECR | 0.768348 | 3 | 0 | 3 |
| ACTR3B | SRRM5 | 0.767586 | 3 | 0 | 3 |
| ACTR3B | STAC2 | 0.723933 | 3 | 0 | 3 |
| ACTR3B | OLIG3 | 0.713161 | 3 | 0 | 3 |
| ACTR3B | KIAA1671 | 0.710563 | 3 | 0 | 3 |
| ACTR3B | NECAB3 | 0.70906 | 3 | 0 | 3 |
| ACTR3B | CCDC77 | 0.689986 | 3 | 0 | 3 |
| ACTR3B | CORO2A | 0.68565 | 3 | 0 | 3 |
| ACTR3B | MCM7 | 0.681814 | 8 | 0 | 8 |
| ACTR3B | HOXB9 | 0.678559 | 3 | 0 | 3 |
| ACTR3B | RELB | 0.67346 | 7 | 0 | 6 |
| ACTR3B | VWDE | 0.67147 | 3 | 0 | 3 |
| ACTR3B | IRF6 | 0.670322 | 3 | 0 | 3 |
| ACTR3B | MIIP | 0.668557 | 5 | 0 | 4 |
| ACTR3B | HAUS8 | 0.667126 | 4 | 0 | 4 |
| ACTR3B | TMEM120B | 0.664928 | 4 | 0 | 3 |
| ACTR3B | FOXJ1 | 0.664148 | 4 | 0 | 3 |
| ACTR3B | PPP2R5D | 0.663587 | 3 | 0 | 3 |
| ACTR3B | MCM2 | 0.660289 | 9 | 0 | 8 |
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