| Full name: WD repeat and FYVE domain containing 1 | Alias Symbol: KIAA1435|FENS-1|WDF1|ZFYVE17 | ||
| Type: protein-coding gene | Cytoband: 2q36.1 | ||
| Entrez ID: 57590 | HGNC ID: HGNC:20451 | Ensembl Gene: ENSG00000085449 | OMIM ID: 618080 |
| Drug and gene relationship at DGIdb | |||
Expression of WDFY1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDFY1 | 57590 | 224800_at | -0.1261 | 0.8155 | |
| GSE26886 | WDFY1 | 57590 | 224800_at | -1.8837 | 0.0000 | |
| GSE45670 | WDFY1 | 57590 | 224800_at | -0.0461 | 0.8579 | |
| GSE53622 | WDFY1 | 57590 | 105105 | 0.1690 | 0.0220 | |
| GSE53624 | WDFY1 | 57590 | 105105 | -0.0428 | 0.6861 | |
| GSE63941 | WDFY1 | 57590 | 224800_at | -1.8222 | 0.0016 | |
| GSE77861 | WDFY1 | 57590 | 224800_at | -0.3601 | 0.1178 | |
| GSE97050 | WDFY1 | 57590 | A_23_P502797 | 0.3225 | 0.3524 | |
| SRP007169 | WDFY1 | 57590 | RNAseq | -0.1830 | 0.5817 | |
| SRP008496 | WDFY1 | 57590 | RNAseq | -0.1472 | 0.4811 | |
| SRP064894 | WDFY1 | 57590 | RNAseq | 0.2980 | 0.1973 | |
| SRP133303 | WDFY1 | 57590 | RNAseq | 0.3921 | 0.0107 | |
| SRP159526 | WDFY1 | 57590 | RNAseq | -0.0504 | 0.8924 | |
| SRP193095 | WDFY1 | 57590 | RNAseq | -0.2964 | 0.0270 | |
| SRP219564 | WDFY1 | 57590 | RNAseq | 0.2681 | 0.5269 | |
| TCGA | WDFY1 | 57590 | RNAseq | -0.0044 | 0.9283 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by WDFY1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDFY1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDFY1 | 57590 | 2 | 12 | 16 | |
| GSE20123 | WDFY1 | 57590 | 2 | 12 | 16 | |
| GSE43470 | WDFY1 | 57590 | 0 | 7 | 36 | |
| GSE46452 | WDFY1 | 57590 | 0 | 5 | 54 | |
| GSE47630 | WDFY1 | 57590 | 4 | 5 | 31 | |
| GSE54993 | WDFY1 | 57590 | 1 | 2 | 67 | |
| GSE54994 | WDFY1 | 57590 | 7 | 10 | 36 | |
| GSE60625 | WDFY1 | 57590 | 3 | 0 | 8 | |
| GSE74703 | WDFY1 | 57590 | 0 | 6 | 30 | |
| GSE74704 | WDFY1 | 57590 | 2 | 6 | 12 | |
| TCGA | WDFY1 | 57590 | 13 | 27 | 56 |
Total number of gains: 34; Total number of losses: 92; Total Number of normals: 362.
Somatic mutations of WDFY1:
Generating mutation plots.
Highly correlated genes for WDFY1:
Showing top 20/866 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDFY1 | TOM1 | 0.830426 | 3 | 0 | 3 |
| WDFY1 | GLUD2 | 0.81627 | 3 | 0 | 3 |
| WDFY1 | KIAA0556 | 0.802781 | 3 | 0 | 3 |
| WDFY1 | ZFC3H1 | 0.796286 | 3 | 0 | 3 |
| WDFY1 | SGMS1 | 0.794743 | 3 | 0 | 3 |
| WDFY1 | CHMP5 | 0.786547 | 3 | 0 | 3 |
| WDFY1 | ERI2 | 0.785267 | 3 | 0 | 3 |
| WDFY1 | CLPX | 0.783571 | 3 | 0 | 3 |
| WDFY1 | SAR1B | 0.775575 | 3 | 0 | 3 |
| WDFY1 | AKR7A2 | 0.771717 | 3 | 0 | 3 |
| WDFY1 | GALNT11 | 0.771603 | 3 | 0 | 3 |
| WDFY1 | PRDM10 | 0.769248 | 3 | 0 | 3 |
| WDFY1 | ARF6 | 0.768167 | 4 | 0 | 4 |
| WDFY1 | ATP6V1D | 0.768057 | 3 | 0 | 3 |
| WDFY1 | ACTR2 | 0.766703 | 4 | 0 | 4 |
| WDFY1 | FGGY | 0.761878 | 3 | 0 | 3 |
| WDFY1 | PARG | 0.757822 | 3 | 0 | 3 |
| WDFY1 | TOPORS | 0.757306 | 3 | 0 | 3 |
| WDFY1 | GPR157 | 0.757059 | 3 | 0 | 3 |
| WDFY1 | NPAT | 0.756819 | 3 | 0 | 3 |
For details and further investigation, click here
