| Full name: leucine rich repeat containing 40 | Alias Symbol: FLJ20331 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 55631 | HGNC ID: HGNC:26004 | Ensembl Gene: ENSG00000066557 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC40:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC40 | 55631 | 218577_at | -0.1826 | 0.6159 | |
| GSE20347 | LRRC40 | 55631 | 218577_at | 0.0325 | 0.8601 | |
| GSE23400 | LRRC40 | 55631 | 218577_at | 0.3946 | 0.0001 | |
| GSE26886 | LRRC40 | 55631 | 218577_at | 0.5023 | 0.0516 | |
| GSE29001 | LRRC40 | 55631 | 218577_at | 0.1693 | 0.6811 | |
| GSE38129 | LRRC40 | 55631 | 218577_at | 0.0928 | 0.4914 | |
| GSE45670 | LRRC40 | 55631 | 218577_at | -0.0472 | 0.7581 | |
| GSE53622 | LRRC40 | 55631 | 31529 | 0.0115 | 0.9055 | |
| GSE53624 | LRRC40 | 55631 | 31529 | 0.1269 | 0.0447 | |
| GSE63941 | LRRC40 | 55631 | 218577_at | -0.0711 | 0.9176 | |
| GSE77861 | LRRC40 | 55631 | 218577_at | -0.2926 | 0.4161 | |
| GSE97050 | LRRC40 | 55631 | A_23_P148969 | 0.0890 | 0.7006 | |
| SRP007169 | LRRC40 | 55631 | RNAseq | 0.0854 | 0.8137 | |
| SRP008496 | LRRC40 | 55631 | RNAseq | -0.1481 | 0.5141 | |
| SRP064894 | LRRC40 | 55631 | RNAseq | -0.0139 | 0.9644 | |
| SRP133303 | LRRC40 | 55631 | RNAseq | 0.5358 | 0.0045 | |
| SRP159526 | LRRC40 | 55631 | RNAseq | -0.5098 | 0.0241 | |
| SRP193095 | LRRC40 | 55631 | RNAseq | -0.2099 | 0.0693 | |
| SRP219564 | LRRC40 | 55631 | RNAseq | 0.0168 | 0.9692 | |
| TCGA | LRRC40 | 55631 | RNAseq | 0.0679 | 0.2343 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC40 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC40:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC40 | 55631 | 2 | 6 | 22 | |
| GSE20123 | LRRC40 | 55631 | 2 | 5 | 23 | |
| GSE43470 | LRRC40 | 55631 | 4 | 4 | 35 | |
| GSE46452 | LRRC40 | 55631 | 0 | 1 | 58 | |
| GSE47630 | LRRC40 | 55631 | 7 | 6 | 27 | |
| GSE54993 | LRRC40 | 55631 | 0 | 0 | 70 | |
| GSE54994 | LRRC40 | 55631 | 6 | 4 | 43 | |
| GSE60625 | LRRC40 | 55631 | 0 | 0 | 11 | |
| GSE74703 | LRRC40 | 55631 | 3 | 3 | 30 | |
| GSE74704 | LRRC40 | 55631 | 1 | 2 | 17 | |
| TCGA | LRRC40 | 55631 | 8 | 22 | 66 |
Total number of gains: 33; Total number of losses: 53; Total Number of normals: 402.
Somatic mutations of LRRC40:
Generating mutation plots.
Highly correlated genes for LRRC40:
Showing top 20/447 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC40 | ANAPC4 | 0.835394 | 3 | 0 | 3 |
| LRRC40 | YME1L1 | 0.792441 | 3 | 0 | 3 |
| LRRC40 | CYTH3 | 0.788858 | 3 | 0 | 3 |
| LRRC40 | SIN3A | 0.784225 | 3 | 0 | 3 |
| LRRC40 | OGFOD1 | 0.768984 | 3 | 0 | 3 |
| LRRC40 | FCF1 | 0.760506 | 3 | 0 | 3 |
| LRRC40 | CETN3 | 0.756148 | 3 | 0 | 3 |
| LRRC40 | SIAH1 | 0.749002 | 3 | 0 | 3 |
| LRRC40 | PPHLN1 | 0.747062 | 3 | 0 | 3 |
| LRRC40 | IPMK | 0.729278 | 3 | 0 | 3 |
| LRRC40 | ALDH1A3 | 0.722781 | 3 | 0 | 3 |
| LRRC40 | CDC42SE2 | 0.719968 | 3 | 0 | 3 |
| LRRC40 | STAM | 0.719777 | 4 | 0 | 3 |
| LRRC40 | ANKRD13C | 0.715184 | 6 | 0 | 6 |
| LRRC40 | SSU72 | 0.71098 | 3 | 0 | 3 |
| LRRC40 | PRRC2C | 0.709566 | 4 | 0 | 4 |
| LRRC40 | WDR47 | 0.707843 | 4 | 0 | 3 |
| LRRC40 | HERPUD2 | 0.699113 | 5 | 0 | 5 |
| LRRC40 | LMNA | 0.698941 | 3 | 0 | 3 |
| LRRC40 | MYL12B | 0.693538 | 3 | 0 | 3 |
For details and further investigation, click here
