| Full name: eukaryotic translation initiation factor 4E nuclear import factor 1 | Alias Symbol: 4E-T|FLJ21601|Clast4|2610509L04Rik | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 56478 | HGNC ID: HGNC:16687 | Ensembl Gene: ENSG00000184708 | OMIM ID: 607445 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of EIF4ENIF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF4ENIF1 | 56478 | 218626_at | -0.2894 | 0.1425 | |
| GSE20347 | EIF4ENIF1 | 56478 | 218626_at | -0.2146 | 0.0892 | |
| GSE23400 | EIF4ENIF1 | 56478 | 218626_at | -0.2384 | 0.0002 | |
| GSE26886 | EIF4ENIF1 | 56478 | 218626_at | -0.5172 | 0.0086 | |
| GSE29001 | EIF4ENIF1 | 56478 | 218626_at | -0.1380 | 0.5219 | |
| GSE38129 | EIF4ENIF1 | 56478 | 218626_at | -0.2622 | 0.0224 | |
| GSE45670 | EIF4ENIF1 | 56478 | 218626_at | -0.2125 | 0.0901 | |
| GSE53622 | EIF4ENIF1 | 56478 | 51399 | -0.3301 | 0.0000 | |
| GSE53624 | EIF4ENIF1 | 56478 | 51399 | -0.2172 | 0.0005 | |
| GSE63941 | EIF4ENIF1 | 56478 | 218626_at | -0.5533 | 0.1320 | |
| GSE77861 | EIF4ENIF1 | 56478 | 218626_at | 0.0676 | 0.7222 | |
| GSE97050 | EIF4ENIF1 | 56478 | A_33_P3367575 | -0.3478 | 0.1917 | |
| SRP007169 | EIF4ENIF1 | 56478 | RNAseq | -0.1816 | 0.6478 | |
| SRP008496 | EIF4ENIF1 | 56478 | RNAseq | 0.0150 | 0.9481 | |
| SRP064894 | EIF4ENIF1 | 56478 | RNAseq | -0.1181 | 0.4145 | |
| SRP133303 | EIF4ENIF1 | 56478 | RNAseq | -0.3380 | 0.0014 | |
| SRP159526 | EIF4ENIF1 | 56478 | RNAseq | -0.1517 | 0.4398 | |
| SRP193095 | EIF4ENIF1 | 56478 | RNAseq | -0.1332 | 0.1817 | |
| SRP219564 | EIF4ENIF1 | 56478 | RNAseq | -0.1564 | 0.5046 | |
| TCGA | EIF4ENIF1 | 56478 | RNAseq | -0.0848 | 0.0946 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF4ENIF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF4ENIF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF4ENIF1 | 56478 | 4 | 5 | 21 | |
| GSE20123 | EIF4ENIF1 | 56478 | 4 | 4 | 22 | |
| GSE43470 | EIF4ENIF1 | 56478 | 4 | 5 | 34 | |
| GSE46452 | EIF4ENIF1 | 56478 | 31 | 1 | 27 | |
| GSE47630 | EIF4ENIF1 | 56478 | 8 | 5 | 27 | |
| GSE54993 | EIF4ENIF1 | 56478 | 3 | 6 | 61 | |
| GSE54994 | EIF4ENIF1 | 56478 | 12 | 8 | 33 | |
| GSE60625 | EIF4ENIF1 | 56478 | 5 | 0 | 6 | |
| GSE74703 | EIF4ENIF1 | 56478 | 4 | 5 | 27 | |
| GSE74704 | EIF4ENIF1 | 56478 | 1 | 1 | 18 | |
| TCGA | EIF4ENIF1 | 56478 | 27 | 16 | 53 |
Total number of gains: 103; Total number of losses: 56; Total Number of normals: 329.
Somatic mutations of EIF4ENIF1:
Generating mutation plots.
Highly correlated genes for EIF4ENIF1:
Showing top 20/574 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF4ENIF1 | FAM120B | 0.817061 | 3 | 0 | 3 |
| EIF4ENIF1 | FMO3 | 0.792518 | 3 | 0 | 3 |
| EIF4ENIF1 | AIFM1 | 0.780051 | 3 | 0 | 3 |
| EIF4ENIF1 | SOCS6 | 0.771679 | 3 | 0 | 3 |
| EIF4ENIF1 | PDK2 | 0.760235 | 3 | 0 | 3 |
| EIF4ENIF1 | PLEKHF2 | 0.759948 | 3 | 0 | 3 |
| EIF4ENIF1 | LONRF2 | 0.751437 | 3 | 0 | 3 |
| EIF4ENIF1 | SLMAP | 0.751175 | 4 | 0 | 4 |
| EIF4ENIF1 | HDHD2 | 0.745409 | 3 | 0 | 3 |
| EIF4ENIF1 | ACAA1 | 0.744887 | 3 | 0 | 3 |
| EIF4ENIF1 | S1PR3 | 0.740124 | 3 | 0 | 3 |
| EIF4ENIF1 | FAM120AOS | 0.735041 | 4 | 0 | 4 |
| EIF4ENIF1 | BEX5 | 0.722801 | 3 | 0 | 3 |
| EIF4ENIF1 | PPID | 0.71935 | 3 | 0 | 3 |
| EIF4ENIF1 | HDAC11 | 0.718742 | 3 | 0 | 3 |
| EIF4ENIF1 | FAM32A | 0.717804 | 3 | 0 | 3 |
| EIF4ENIF1 | MSI2 | 0.711685 | 3 | 0 | 3 |
| EIF4ENIF1 | DNAJB9 | 0.711205 | 3 | 0 | 3 |
| EIF4ENIF1 | AZI2 | 0.710429 | 4 | 0 | 4 |
| EIF4ENIF1 | PIK3R1 | 0.710234 | 3 | 0 | 3 |
For details and further investigation, click here
