| Full name: family with sequence similarity 126 member B | Alias Symbol: MGC39518|HYCC2 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 285172 | HGNC ID: HGNC:28593 | Ensembl Gene: ENSG00000155744 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM126B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM126B | 285172 | 229460_at | 0.1472 | 0.8271 | |
| GSE26886 | FAM126B | 285172 | 229460_at | -1.9980 | 0.0000 | |
| GSE45670 | FAM126B | 285172 | 229460_at | -0.2825 | 0.0591 | |
| GSE53622 | FAM126B | 285172 | 86451 | -0.3227 | 0.0000 | |
| GSE53624 | FAM126B | 285172 | 86451 | -0.6556 | 0.0000 | |
| GSE63941 | FAM126B | 285172 | 229460_at | -1.2416 | 0.0698 | |
| GSE77861 | FAM126B | 285172 | 229460_at | -1.0601 | 0.0407 | |
| GSE97050 | FAM126B | 285172 | A_23_P334864 | 0.0801 | 0.8295 | |
| SRP007169 | FAM126B | 285172 | RNAseq | -1.8962 | 0.0002 | |
| SRP008496 | FAM126B | 285172 | RNAseq | -1.7718 | 0.0000 | |
| SRP064894 | FAM126B | 285172 | RNAseq | -1.0640 | 0.0000 | |
| SRP133303 | FAM126B | 285172 | RNAseq | -0.3420 | 0.0172 | |
| SRP159526 | FAM126B | 285172 | RNAseq | -0.9149 | 0.0000 | |
| SRP193095 | FAM126B | 285172 | RNAseq | -1.1337 | 0.0000 | |
| SRP219564 | FAM126B | 285172 | RNAseq | -0.8145 | 0.0402 | |
| TCGA | FAM126B | 285172 | RNAseq | -0.1462 | 0.0226 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by FAM126B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM126B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM126B | 285172 | 6 | 4 | 20 | |
| GSE20123 | FAM126B | 285172 | 6 | 4 | 20 | |
| GSE43470 | FAM126B | 285172 | 1 | 1 | 41 | |
| GSE46452 | FAM126B | 285172 | 1 | 4 | 54 | |
| GSE47630 | FAM126B | 285172 | 4 | 5 | 31 | |
| GSE54993 | FAM126B | 285172 | 0 | 3 | 67 | |
| GSE54994 | FAM126B | 285172 | 10 | 8 | 35 | |
| GSE60625 | FAM126B | 285172 | 0 | 3 | 8 | |
| GSE74703 | FAM126B | 285172 | 1 | 1 | 34 | |
| GSE74704 | FAM126B | 285172 | 3 | 2 | 15 | |
| TCGA | FAM126B | 285172 | 22 | 10 | 64 |
Total number of gains: 54; Total number of losses: 45; Total Number of normals: 389.
Somatic mutations of FAM126B:
Generating mutation plots.
Highly correlated genes for FAM126B:
Showing top 20/988 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM126B | TMEM167A | 0.777245 | 3 | 0 | 3 |
| FAM126B | KLHL20 | 0.739572 | 3 | 0 | 3 |
| FAM126B | NAGK | 0.731228 | 6 | 0 | 6 |
| FAM126B | C6orf62 | 0.730419 | 4 | 0 | 4 |
| FAM126B | UBE2J1 | 0.727539 | 3 | 0 | 3 |
| FAM126B | MFSD5 | 0.725313 | 6 | 0 | 6 |
| FAM126B | GDPD3 | 0.720208 | 5 | 0 | 5 |
| FAM126B | CSTB | 0.7191 | 5 | 0 | 5 |
| FAM126B | GRPEL2 | 0.717999 | 7 | 0 | 6 |
| FAM126B | FAM214A | 0.71697 | 5 | 0 | 5 |
| FAM126B | FBXO3 | 0.715206 | 5 | 0 | 5 |
| FAM126B | ACAA1 | 0.714849 | 5 | 0 | 5 |
| FAM126B | UBL3 | 0.713924 | 5 | 0 | 5 |
| FAM126B | GBP6 | 0.713905 | 4 | 0 | 3 |
| FAM126B | GALNT11 | 0.713056 | 3 | 0 | 3 |
| FAM126B | CARD16 | 0.712964 | 3 | 0 | 3 |
| FAM126B | INO80D | 0.709652 | 5 | 0 | 5 |
| FAM126B | KLHL28 | 0.709302 | 3 | 0 | 3 |
| FAM126B | ZNF217 | 0.708556 | 4 | 0 | 4 |
| FAM126B | PSCA | 0.707448 | 3 | 0 | 3 |
For details and further investigation, click here
