| Full name: WD repeat domain 61 | Alias Symbol: REC14 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 80349 | HGNC ID: HGNC:30300 | Ensembl Gene: ENSG00000140395 | OMIM ID: 609540 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of WDR61:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR61 | 80349 | 221532_s_at | -0.2678 | 0.6692 | |
| GSE20347 | WDR61 | 80349 | 221532_s_at | -0.2350 | 0.2796 | |
| GSE23400 | WDR61 | 80349 | 221532_s_at | -0.0188 | 0.8133 | |
| GSE26886 | WDR61 | 80349 | 221532_s_at | -0.5038 | 0.0044 | |
| GSE29001 | WDR61 | 80349 | 221532_s_at | -0.2723 | 0.4109 | |
| GSE38129 | WDR61 | 80349 | 221532_s_at | 0.0718 | 0.6455 | |
| GSE45670 | WDR61 | 80349 | 221532_s_at | -0.3196 | 0.0078 | |
| GSE53622 | WDR61 | 80349 | 27128 | -0.1628 | 0.0250 | |
| GSE53624 | WDR61 | 80349 | 27128 | -0.2887 | 0.0032 | |
| GSE63941 | WDR61 | 80349 | 221532_s_at | -0.1775 | 0.7290 | |
| GSE77861 | WDR61 | 80349 | 232075_at | -0.2771 | 0.2580 | |
| GSE97050 | WDR61 | 80349 | A_23_P49021 | -0.0594 | 0.7957 | |
| SRP007169 | WDR61 | 80349 | RNAseq | -0.8096 | 0.0110 | |
| SRP008496 | WDR61 | 80349 | RNAseq | -0.7407 | 0.0001 | |
| SRP064894 | WDR61 | 80349 | RNAseq | -0.1554 | 0.2644 | |
| SRP133303 | WDR61 | 80349 | RNAseq | -0.0395 | 0.8192 | |
| SRP159526 | WDR61 | 80349 | RNAseq | 0.2788 | 0.2636 | |
| SRP193095 | WDR61 | 80349 | RNAseq | -0.2947 | 0.0120 | |
| SRP219564 | WDR61 | 80349 | RNAseq | -0.1558 | 0.4183 | |
| TCGA | WDR61 | 80349 | RNAseq | 0.0639 | 0.2296 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR61 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR61:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR61 | 80349 | 7 | 1 | 22 | |
| GSE20123 | WDR61 | 80349 | 7 | 1 | 22 | |
| GSE43470 | WDR61 | 80349 | 4 | 5 | 34 | |
| GSE46452 | WDR61 | 80349 | 3 | 7 | 49 | |
| GSE47630 | WDR61 | 80349 | 8 | 10 | 22 | |
| GSE54993 | WDR61 | 80349 | 5 | 6 | 59 | |
| GSE54994 | WDR61 | 80349 | 5 | 6 | 42 | |
| GSE60625 | WDR61 | 80349 | 4 | 0 | 7 | |
| GSE74703 | WDR61 | 80349 | 4 | 3 | 29 | |
| GSE74704 | WDR61 | 80349 | 3 | 1 | 16 | |
| TCGA | WDR61 | 80349 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 55; Total Number of normals: 369.
Somatic mutations of WDR61:
Generating mutation plots.
Highly correlated genes for WDR61:
Showing top 20/847 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR61 | SLC12A6 | 0.764814 | 3 | 0 | 3 |
| WDR61 | RWDD2A | 0.755941 | 3 | 0 | 3 |
| WDR61 | CPA3 | 0.753481 | 3 | 0 | 3 |
| WDR61 | SCO1 | 0.752917 | 4 | 0 | 4 |
| WDR61 | SAMD8 | 0.750503 | 3 | 0 | 3 |
| WDR61 | SNX12 | 0.749947 | 3 | 0 | 3 |
| WDR61 | CCNYL1 | 0.740972 | 4 | 0 | 4 |
| WDR61 | COX15 | 0.739069 | 3 | 0 | 3 |
| WDR61 | TMED4 | 0.735353 | 3 | 0 | 3 |
| WDR61 | CRLS1 | 0.73385 | 3 | 0 | 3 |
| WDR61 | ACER3 | 0.730375 | 3 | 0 | 3 |
| WDR61 | ANKRD13C | 0.728452 | 4 | 0 | 3 |
| WDR61 | GMCL1 | 0.720816 | 3 | 0 | 3 |
| WDR61 | PAIP2 | 0.716147 | 3 | 0 | 3 |
| WDR61 | ETFA | 0.713352 | 13 | 0 | 11 |
| WDR61 | SNAPIN | 0.712986 | 3 | 0 | 3 |
| WDR61 | CPT2 | 0.710467 | 4 | 0 | 3 |
| WDR61 | HDAC5 | 0.708539 | 3 | 0 | 3 |
| WDR61 | GLRX3 | 0.707646 | 7 | 0 | 7 |
| WDR61 | WDFY1 | 0.702699 | 4 | 0 | 4 |
For details and further investigation, click here
